Unipro ID Name Function Host Pathogen Source Length Domain Subcellular location TargetP mPloc Status Q63K50_BURPS Uncharacterized protein GN=BPSS1516 Unknown Animals and Humans Burkholderia pseudomallei (strain K96243) Experimentally validated effector 469 Phosphorylase superfamily Unknown Any other location Cytoplasm Complete Q87GF9_VIBPA Uncharacterized protein GN=VPA1357 Unknown Shellfishes Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) Experimentally validated effector 1622 Apolipoprotein L Unknown Any other location Nucleus Complete Q7BEN0_SHIFL Enterotoxin Unknown Animals and Humans Shigella flexneri 5a Experimentally validated effector 565 ShET2 enterotoxin, N-terminal region Unknown Any other location Cytoplasm Complete IPAA_SHIFL Invasin IpaA Rapidly associates with the first 265 amino acids of vinculin after bacteria-cell contact. This interaction is critical for efficient Shigella uptake. IpaA acts as a potent activator of vinculin and increase its ability to interact with F-actin. The complex IpaA-vinculin induces F-actin depolymerization along with the occasional formation of actin filament bundles. Animals and Humans Shigella flexneri Experimentally validated effector 633 Salmonella invasion protein A Cytosol Any other location Nucleus Complete IPAB_SHIFL Invasin IpaB Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Forms a pore with IpaC, which is inserted into the host cell membrane through the Mxi/Spa apparatus, during cell contact. This pore probably allows the translocation of IpaA. IpaB has also been found to be necessary and sufficient to activate macrophage apoptosis by binding to interleukin-1 beta converting enzyme (ICE). Has also been shown to be important, along with IpaD, to block or regulate secretion through the Mxi/Spa translocon in the presence or absence of the secretion signal, respectively. Through interaction with host Humans MAD2L2, constitutively activates the anaphase-promoting complex APC and induces a cell cycle arrest to prevent epithelial renewal in order to promote bacterial colonization. Animals and Humans Shigella flexneri Experimentally validated effector 580 Secretion system effector C (SseC) like family Membrane;Nucleus Any other location Cytoplasm Complete IPAC_SHIFL Invasin IpaC Forms a pore with IpaB, which is inserted into host cell membrane through the Mxi/Spa apparatus, during cell contact. This pore probably allows the translocation of IpaA. The C-terminus of IpaC could be involved in actin polymerization that leads to the cell extension formation and its N-terminus could be involved in the conversion of filopodial extensions into lamellipodial extension. Most extensions results from Cdc42 activation by IpaC whereas the lamellipodial extensions result from the Rac activation by Cdc42. Animals and Humans Shigella flexneri Experimentally validated effector 363 Salmonella-Shigella invasin protein C (IpaC_SipC) Membrane Any other location Nucleus Complete IPAD_SHIFL Invasin IpaD Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal. Animals and Humans Shigella flexneri Experimentally validated effector 332 The N-terminal domain is an intra-molecular chaperone that prevents premature oligomerization of the residues on the coiled-coil region that are involved in interactions with the needle and/or itself. The residues in the C-terminal domain probably form oligomeric structures at the tip of the needle that are responsible for the regulation of secretion of other effectors. Localizes to the tip of the external secretion needle that is part of the TTSS apparatus Any other location Nucleus Complete Q6XVT8_SHIFL IpaH1.4 Unknown Animals and Humans Shigella flexneri Experimentally validated effector 575 Type III secretion system leucine rich repeat protein;C-terminal novel E3 ligase, LRR-interacting. Unknown Any other location Nucleus Complete Q326T5_SHIDS IpaJ IpaJ cleaves an array of N-myristoylated proteins involved in cellular growth, signal transduction, autophagasome maturation and organelle function. Animals and Humans Shigella flexneri Experimentally validated effector 227 None Cytoplasm Any other location Membrane Complete Q326S7_SHIDS IpgB1 IpgB1 is secreted via the TTSS into epithelial cells and plays a major role in producing membrane ruffles via stimulation of Rac1 and Cdc42 activities, thus promoting bacterial invasion of epithelial cells. Animals and Humans Shigella dysenteriae serotype 1 (strain Sd197) Experimentally validated effector 208 IpaB/EvcA family Membrane Any other location Nucleus Complete Q9AJW7_SHIFL IpgB2 Unknown Animals and Humans Shigella flexneri Experimentally validated effector 188 IpaB/EvcA family Unknown Any other location Cytoplasm Complete IPGD_SHIFL IpgD Converts phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to PtdIns 5-P. IpgD is injected by Shigella into the host cell and is required for invasion. The accumulation of PtdIns 5-P causes membrane ruffling and actin cytoskeleton rearrangements at the entry site. Acts in concert with IpaA to coordinate and control the membrane and cytoskeletal rearrangements induced early after invasion of the host cell. Animals and Humans Shigella flexneri Experimentally validated effector 538 Contains the consensus sequence Cys-X(5)-Arg characteristic of Mg-independent phosphatases Cytoplasm Any other location Cytoplasm Complete VIRA_SHIFL VirA Alpha-tubulin-specific protease that is required for entry into epithelial cells and for subsequent intra- and intercellular spreading. Contributes to bacterial entry into epithelial cells by inducing microtubule (MT) destabilization and the formation of membrane ruffles. The membrane ruffling evoked by VirA results from the activation of host rac1, which is associated with the destruction of MT networks. Creates a tunnel inside the host cell cytoplasm by breaking down the microtubule infrastructure. This facilitates the bacteriums movement through the cytoplasm and also helps other bacteria move faster during the invasion of the eukaryotic cell. Is absolutely required for virulence. Animals and Humans Shigella flexneri Experimentally validated effector 400 Tubulin-binding domain Cytoplasm Any other location Nucleus Complete YOPE_YERPE YopE Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis. Animals and Humans Yersinia pestis Experimentally validated effector 219 1YopE, N terminal; 2Yersinia virulence determinant (YopE) Cell outer membrane Any other location Cytoplasm Complete YOPH_YERPS YopH Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages. Animals and Humans Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 468 Tyrosine-protein phosphatase Unknown Any other location Membrane Complete YOPQ_YEREN YopQ May function as a virulence determinant. Animals and Humans Yersinia enterocolitica Experimentally validated effector 182 None Unknown Any other location Cytoplasm Complete Q84GR3_YEREN YopP Unknown Animals and Humans Yersinia enterocolitica Experimentally validated effector 288 YopJ Serine/Threonine acetyltransferase Unknown Any other location Cytoplasm Complete Q93KQ6_YEREN YopO Unknown Animals and Humans Yersinia enterocolitica Experimentally validated effector 729 Protein kinase domain; Rac1-binding domain Unknown Any other location Cytoplasm, Complete Q7BRZ4_YEREN YopR Unknown Animals and Humans Yersinia enterocolitica Experimentally validated effector 165 YopR Core Unknown Mitochondrion Cytoplasm Complete Q9Z8L4_CHLPN CopN Unknown Animals and Humans Chlamydia pneumoniae (Chlamydophila pneumoniae) Experimentally validated effector 399 HrpJ-like domain Unknown Any other location Cytoplasm Complete Q824H6_CHLCV Uncharacterized protein Unknown Guinea-pigs Chlamydophila caviae (strain GPIC) Experimentally validated effector 880 DUF1547 Unknown Any other location Nucleus Complete Q46210_CHLCI Inclusion membrane localised protein Unknown Guinea-pigs Chlamydophila caviae Experimentally validated effector 355 IncA protein Unknown Any other location Cytoplasm Complete O30783_CHLCI Inclusion membrane protein C Unknown Guinea-pigs Chlamydophila caviae Experimentally validated effector 186 SCAMP family;Fumarate reductase subunit C Unknown Any other location Membrane Complete SLRP_SALTY E3 ubiquitin-protein ligase SlrP Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Can ubiquitinate both ubiquitin and host TXN (Thioredoxin). Leads to significant decrease of thioredoxin activity and increase of host cell death. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 765 The LRR (leucine-rich repeat) domain forms a slightly curved solenoid and may mediate interaction with target proteins. Cytoplasm Any other location Cytoplasm Complete SOPB_SALTY Inositol phosphate phosphatase SopB Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 561 Contains the consensus sequence Cys-X(5)-Arg characteristic of Mg-independent phosphatases. Unknown Any other location Cytoplasm Complete Q57PP1_SALCH Secretion system apparatus SsaB Unknown Animals and Humans Salmonella choleraesuis (strain SC-B67) Experimentally validated effector 133 None Unknown Any other location Membrane Complete SSEA_SALTY Type III secretion system chaperone SseA Functions as a type III secretion system (TTSS) chaperone, which is required for SseB and SseD accumulation and secretion. May have a direct role in secretion of SseB and SseD, or may facilitate their correct folding, for efficient secretion and function. Required for survival and replication within epithelial cells and macrophages. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 108 The N-terminal region is dispensable for binding and stabilizing SseB, but is essential for export of SseB to the surface of the bacterium. Cytoplasm Any other location Nucleus Complete SSEB_SALTY Secreted effector protein SseB Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells. SseB is required for correct localization of SseC and SseD on the bacterial cell surface. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 196 EspA-like secreted protein Cell surface Any other location Cytoplasm Complete SSEC_SALTY Secreted effector protein SseC Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 484 Secretion system effector C (SseC) like family Cell surface Mitochondrion Mitochondrion Complete SSED_SALTY Secreted effector protein SseD Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 195 None Cell surface Secretory pathway Mitochondrion, Complete Q57PN2_SALCH Secretion system effector SseE Unknown Animals and Humans Salmonella choleraesuis (strain SC-B67) Experimentally validated effector 138 Type III secretion system regulator (LcrR) Unknown Any other location Endoplasmic Complete O84951_SALTM SseF Unknown Animals and Humans Salmonella typhimurium Experimentally validated effector 260 None Unknown Any other location Membrane Complete O84952_SALTM SseG Unknown Animals and Humans Salmonella typhimurium Experimentally validated effector 229 None Unknown Any other location Membrane Complete SOPE2_SALTY Guanine nucleotide exchange factor sopE2 Activator for CDC42 by directly engaging this Rho GTPase and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Also activates NF-kB, p38 and ERK kinases, which are known to be involved in the induction of IL-8 expression. Chaperone InvB is required for secretion, translocation and stabilization of intracellular levels of sopE2. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 240 Salmonella type III secretion SopE effector N-terminus; SopE GEF domain Unknown Any other location Nucleus Complete SOPA_SALTY E3 ubiquitin-protein ligase SopA Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Required for inducing polymorphonuclear leukocytes migration across the intestinal epithelium. Preferentially uses host UBE2D1 (UBCH5A), UBE2D2 (UBCH5B) and UBE2L3 (UBCH7) as E2 ubiquitin-conjugating enzymes. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 782 The N-terminal 45 amino acids are necessary and sufficient for secretion and translocation into host cells. This N-terminal region binds the SpaK/InvB chaperone. Contains a C-terminal HECT-like domain Unknown Any other location Nucleus Complete SPTP_SALTY Secreted effector protein SptP Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 543 Tyrosine-protein phosphatase Host cytoplasm Any other location Nucleus Complete SIPC_SALTY Cell invasion protein SipC Actin-binding protein that interferes with host cell actin cytoskeleton. Nucleates actin polymerization and condensates actin filaments into cables (bundling). SipA potenciates SipC activity and both are required for an efficient bacterial internalization by the host cell. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 409 Salmonella-Shigella invasin protein C (IpaC_SipC) Cell plasma membrane Any other location Nucleus Complete SOPD_SALTY Secreted effector protein SopD Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with SopB, in membrane fission and macropinosome formation during invasion. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 317 Secreted effector protein SopD Cytoplasm Any other location Cytoplasm Complete Q9KWH9_ECOLX Tir Unknown Animals and Humans Escherichia coli Experimentally validated effector 552 Translocated intimin receptor (Tir) N-terminus; Translocated intimin receptor (Tir) intimin-binding domain; Translocated intimin receptor (Tir) C-terminus Unknown Any other location Nucleus Complete B7UM94_ECO27 Translocon EspA Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 192 EspA-like secreted protein Unknown Any other location Nucleus Complete Q8XC86_ECO57 EspB Unknown Animals and Humans Escherichia coli O157:H7 Experimentally validated effector 312 Enterobacterial EspB protein Unknown Any other location Cytoplasm Complete Q7DB81_ECO57 EspD Unknown Animals and Humans Escherichia coli O157:H7 Experimentally validated effector 374 Secretion system effector C (SseC) like family Unknown Any other location Cytoplasm Complete Q7DB85_ECO57 EspF Unknown Animals and Humans Escherichia coli O157:H7 Experimentally validated effector 248 EspF protein repeat Unknown Mitochondrion Nucleus Complete C8U087_ECO10 NleE-like protein Unknown Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 224 Bacteriophage FRD3 protein Unknown Any other location Cytoplasm Complete C8U088_ECO10 NleB-like protein Unknown Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 329 None Unknown Mitochondrion Cytoplasm Complete BIPB_BURPS BipB Plays a role in the bacterium-induced formation of multinucleated giant cell (MNGC), which is formed after host cell fusion, as well as in the intercellular spreading of bacteria and in the induction of apoptosis in macrophages. May act in concert with other effector proteins to induce fusion of host cell membranes. Animals and Humans Burkholderia pseudomallei (strain K96243) Experimentally validated effector 620 Secretion system effector C (SseC) like famil Host membrane Any other location Cytoskeleton Complete BIPC_BURPS BipC Unknown Animals and Humans Burkholderia pseudomallei (strain K96243) Experimentally validated effector 419 Salmonella-Shigella invasin protein C (IpaC_SipC) Unknown Any other location Cytoplasm Complete BIPD_BURPS BipD Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane. Animals and Humans Burkholderia pseudomallei (strain K96243) Experimentally validated effector 310 The N-terminal domain is an intra-molecular chaperone that prevents premature oligomerization of the residues on the coiled-coil region that are involved in interactions with the needle and/or itself. The residues in the C-terminal domain probably form oligomeric structures at the tip of the needle that are responsible for the regulation of secretion of other effectors. Part of the secretion apparatus Any other location Mitochondrion Complete BOPE_BURPS BopE Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells. Animals and Humans Burkholderia pseudomallei (strain K96243) Experimentally validated effector 261 SopE GEF domain Unknown Any other location Cytoplasm Complete Q7VWI4_BORPE Putative outer protein B Unknown Animals and Humans Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) Experimentally validated effector 402 Secretion system effector C (SseC) like family Unknown Mitochondrion Mitochondrion Complete Q84CS5_BORPT Putative uncharacterized protein Unknown Animals and Humans Bordetella pertussis Experimentally validated effector 313 None Unknown Any other location Nucleus Complete D1MWR4_BORPT Transposase Unknown Animals and Humans Bordetella pertussis Experimentally validated effector 316 leucine-zipper of insertion element IS481; rve:Integrase core domain Unknown Mitochondrion Cytoplasm Complete Q84CS9_BORPT BopN Unknown Animals and Humans Bordetella pertussis Experimentally validated effector 365 HrpJ-like domain; TyeA Unknown Any other location Cytoplasm Complete Q9REZ7_BORBO Secreted protein 22 Unknown Animals and Humans Bordetella bronchiseptica (Alcaligenes bronchisepticus) Experimentally validated effector 205 DUF815 Unknown Any other location Nucleus Complete Q7MYD1_PHOLL Plu4750 Unknown Insects Photorhabdus luminescens subsp. laumondii (strain TT01) Experimentally validated effector 316 MSP1_C Unknown Any other location Nucleus Complete B9A807_VIBPH VopL VopL is a bacterial effector that mimics a eukaryotic actin-nucleating protein by containing all of the necessary domains to enable it to potently and directly facilitate the assembly of actin Shellfishes Vibrio parahaemolyticus Experimentally validated effector 466 WH2 motif Unknown Any other location Nucleus Complete B9A810_VIBPH VopC Unknown Shellfishes Vibrio parahaemolyticus Experimentally validated effector 372 Rho-activating domain of cytotoxic necrotizing facto Unknown Any other location Nucleus Complete Q87P38_VIBPA GN=VP1680 Unknown Shellfishes Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) Experimentally validated effector 492 None Unknown Any other location Cytoplasm Complete VOPS_VIBPA VopS Adenylyltransferase involved in virulence by mediating the addition of adenosine 5-monophosphate (AMP) to specific threonine residue of host Rho GTPases RhoA, Rac and Cdc42. The resulting AMPylation prevents the interaction of Rho GTPases with downstream effectors, thereby inhibiting actin assembly in infected cells Shellfishes Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) Experimentally validated effector 387 The fido domain mediates the adenylyltransferase activity unknown Any other location Mitochondrion Complete Q4G4D0_EDWTA EseC Unknown Animals Edwardsiella tarda Experimentally validated effector 506 Secretion system effector C (SseC) like famil Unknown Any other location Mitochondrion Complete D2TKF8_CITRI EspZ Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 100 SepZ Unknown Secretory pathway Membrane Complete D2TKF1_CITRI EspH Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 179 None Unknown Mitochondrion Membrane Complete D2TRY1_CITRI EspJ Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 217 AvrPphF-ORF-2 Unknown Any other location Nucleus Complete D2TTX7_CITRI EspX7 ubiquitin-protein ligase activity Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 782 Pentapeptide_4; SopA; SopA_C Unknown Any other location Membrane Complete D2TJZ4_CITRI NleA/EspI Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 430 None Unknown Any other location Cytoplasm Complete D2TK70_CITRI NleC Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 330 Peptidase_M85(NFkB-p65-degrading zinc protease) Unknown Any other location Nucleus, Complete D2TML3_CITRI NleD Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 235 Peptidase_M91 Unknown Mitochondrion Membrane Complete D2TRX8_CITRI NleF Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 192 None Unknown Any other location Cytoplasm Complete D2TRX7_CITRI NleH Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 293 YrbL-PhoP_reg(PhoP regulatory network protein YrbL) Unknown Any other location Membrane Complete AEXT_AERSA AexT Directly involved in the toxicity for RTG-2 (rainbow trout gonad) fish cells Salmonid Aeromonas salmonicida Experimentally validated effector 475 YopE; ADPrib_exo_Tox(ADP-ribosyltransferase exoenzyme) cytosol Any other location Cytoplasm Complete MXIC_SHIFL MxiC Necessary for the secretion of IPA invasins Animals ang Humans Shigella flexneri Experimentally validated effector 355 HrpJ-like domain cytoplasm Any other location Nucleus Complete Q3YTN8_SHISS MxiL Unknown Animals and Humans Shigella sonnei (strain Ss046) Experimentally validated effector 135 OspE Unknown Any other location Nucleus Complete Q327J1_SHIDS OspB Unknown Animals and Humans Shigella dysenteriae serotype 1 (strain Sd197) Experimentally validated effector 227 DUF2870; DUF4347 Unknown Any other location Nucleus Complete Q327E0_SHIDS OspC1 Unknown Animals and Humans Shigella dysenteriae serotype 1 (strain Sd197) Experimentally validated effector 470 Shigella_OspC Unknown Any other location Nucleus Complete OSPG_SHIFL OspG Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria. Prevents or at least delays host phospho-NF-kappa-B inhibitor alpha (NFKBIA) degradation. Does not phosphorylate E2 enzymes. Animals and Humans Shigella flexneri Experimentally validated effector 196 Choline_kinase Unknown Any other location Membrane Complete SPAN_SHIFL SpaN Required for surface presentation of invasion plasmid antigens. Could play a role in preserving the translocation competence of the ipa antigens. Required for invasion and for secretion of IpaB and IpaD proteins. Animals and Humans Shigella flexneri Experimentally validated effector 292 SPAN(Surface presentation of antigens protein) Cell outer membrane; Peripheral membrane protein Any other location Nucleus Complete Q6R8C5_SODGL YspB Unknown Insects Sodalis glossinidius Experimentally validated effector 658 Secretion system effector C (SseC) like family Unknown Any other location Mitochondrion Complete A2A0Z4_ECOLX Type III secreted effector protein Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete A9ZNG5_ECOLX NleB Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 326 Hemocyanin_N Unknown Any other location Cytoplasm Complete D2TZ32_9ENTR YopB Unknown Nasonia vitripennis and wasps Arsenophonus nasoniae (son-killer infecting Nasonia vitripennis) Experimentally validated effector 376 IpaD(Invasion plasmid antigen IpaD) Unknown Any other location Nucleus Complete YOPM_YERPE YopM Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Animals and Humans Yersinia pestis Experimentally validated effector 409 TTSSLRR:Type III secretion system leucine rich repeat protein Cell outer membrane Any other location Secreted Complete C6USQ3_ECO5T Non-LEE-encoded type III secreted effector nleH2 Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 303 None Unknown Any other location Membrane Complete A2A0X3_ECOLX tccP2 TccP2 is a translocated effector protein, capable of triggering Nck-independent actin polymerization within the eukaryotic cell Animals and Humans Escherichia coli O157:H- Experimentally validated effector 250 EspF cytoplasm Mitochondrion Nucleus Complete A4PDU8_ECOLX Tir-cytoskeleton coupling protein Tir acts as a receptor for the bacterial outer membrane protein intimin Animals and Humans Escherichia coli O103:K+ Experimentally validated effector 344 EspF plasma membrane Mitochondrion Nucleus Complete A4PCI7_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O111:H2 Experimentally validated effector 344 EspF Unknown Mitochondrion Nucleus Complete BOPA_BURM7 BopA Plays a role in mediating bacterial evasion from the host autophagic pathway. Animals and Humans Burkholderia mallei (strain NCTC 10247) Experimentally validated effector 512 SicP-binding Unknown Mitochondrion Golgi Complete A2A0Y6_ECO11 Type III secreted effector protein GN=tccP2 Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete ESFU3_ECO57 EspF(U) Required for efficient pedestal formation in host epithelial cells during infection. Acts as an intermediate between Tir (via host BAIAP2) and host WASL/N-WASP. Directly binds and activates WASL/N-WASP, which stimulates actin polymerization and leads to the formation of actin pedestals at the sites of bacterial adhesion. Animals and Humans Escherichia coli O157:H7 Experimentally validated effector 337 The N-terminal 21 amino acids are necessary and sufficient for translocation into the host cell By similarity. The C-terminal region, composed of several highly conserved proline-rich repeats, interacts with the SH3 domain of BAIAP2 and BAIAP2L1, and the GTPase binding domain (GBD) of WASL/N-WASP and WAS/WASP. The N-terminal translocation signal and two proline-rich repeats are sufficient for triggering actin polymerization, but each additional repeat gives higher activity. cytoplasm Mitochondrion Nucleus Complete A4PDV1_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete SSEL_SALTY Deubiquitinase SseL Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells. Specifically hydrolyzes mono- and polyubiquitin substrates in vitro with a preference for Lys-63-linked ubiquitin chains, suggesting that it interferes with a signaling pathway rather than inhibiting proteasomal-dependent degradation of its targets. Does not possess desumoylating activity. Is required for the Salmonella-induced delayed cytotoxicity in macrophages and full virulence. Is not required for intracellular bacterial replication. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 340 None cytoplasm Any other location Cytoplasm Complete A4PDU5_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 391 EspF Unknown Mitochondrion Nucleus Complete C8UFL1_ECO1A EspH Unknown Animals and Humans Escherichia coli O111:H- (strain 11128 / EHEC) Experimentally validated effector 169 None Unknown Mitochondrion Membrane Complete C8TNQ9_ECO26 EspG cysteine-type endopeptidase activity Animals and Humans Escherichia coli O26:H11 (strain 11368 / EHEC) Experimentally validated effector 398 EspG Unknown Any other location Membrane Complete D2TT37_CITRI NleB1 Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 329 None Unknown Any other location Cytoplasm, Complete B5R8S6_SALG2 SopE Unknown Aves Salmonella gallinarum (strain 287/91 / NCTC 13346) Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete D2TT38_CITRI NleE Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 230 UAE_UbL Unknown Any other location Cytoplasm Complete SSEI_SALTY SseI Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required to maintain a long-term chronic systemic infection in mice. It inhibits normal cell migration of primary macrophages and dendritic cells, by a mechanism that involves interaction with the host factor IQGAP1, an important regulator of the cytoskeleton and cell migration. Also accelerates the systemic spread of infection from the gastrointestinal tract to the bloodstream, probably by interacting with host TRIP6. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 322 Tox-PLDMTX(Dermonecrotoxin of the Papain-like fold) cytoplasm Mitochondrion Cytoplasm Complete SSPH2_SALTY sspH2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 788 The LRR (leucine-rich repeat) domain is involved in autoinhibition of the enzyme activity by interacting with the catalytic domain. cytoplasm Mitochondrion Cytoplasm Complete IPA7_SHIFL Probable E3 ubiquitin-protein ligase ipaH7.8 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Animals and Humans Shigella flexneri Experimentally validated effector 565 The LRR (leucine-rich repeat) domain forms a slightly curved solenoid and may mediate interaction with target proteins. cytoplasm Any other location Nucleus Complete C8TWQ0_ECO10 EspG cysteine-type endopeptidase activity Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 398 EspG Unknown Any other location Nucleus Complete C8TNS7_ECO26 EspZ Unknown Animals and Humans Escherichia coli O26:H11 (strain 11368 / EHEC) Experimentally validated effector 100 SepZ Unknown Any other location Membrane Complete STEC_SALT1 SteC Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase, which is required for SPI-2 TTSS-dependent F-actin meshwork formation in infected host cells. Animals and Humans Salmonella typhimurium (strain 14028s / SGSC 2262) Experimentally validated effector 457 None cytoplasm Any other location Cytoplasm Complete C6V2D0_ECO5T Non-LEE-encoded type III secreted effector GN=nleH1 Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 293 YrbL-PhoP_reg Unknown Any other location Membrane Complete B8ZYG0_ECOLX Type III secretion system, translocated effector protein, LEE associated Unknown Animals and Humans Escherichia coli Experimentally validated effector 203 IpaB_EvcA Unknown Mitochondrion Nucleus Complete A2A0Y3_ECOLX Type III secreted effector protein GN=tccP2 Unknown Animals and Humans Escherichia coli O26:H- Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete YOPT1_YERE8 Cysteine protease yopT1 Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the Humans small GTPase RhoA/ARHA, a regulator of cytoskeleton. Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell. Animals and Humans Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) Experimentally validated effector 322 Peptidase_C58(Yersinia/Haemophilus virulence surface antigen) Cytoplasmic Any other location Membrane Complete BIPC_BURTA BipC Unknown Animals and Humans Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) Experimentally validated effector 409 Salmonella-Shigella invasin protein C (IpaC_SipC) Unknown Any other location Nucleus Complete Q27RI1_AERS4 AopH Unknown Salmonid Aeromonas salmonicida (strain A449) Experimentally validated effector 463 YopH_N Y_phosphatase Unknown Any other location Nucleus Complete Q84GT9_YEREN YopM Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 526 TTSSLRR(Type III secretion system leucine rich repeat protein) Unknown Any other location Secreted Complete SOPB_SALBN SopB Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell Reptiles Salmonella bongori Experimentally validated effector 416 Contains the consensus sequence Cys-X(5)-Arg characteristic of Mg-independent phosphatases Unknown Any other location Cytoplasm Fragment C8TNT6_ECO26 Map Unknown Animals and Humans Escherichia coli O26:H11 (strain 11368 / EHEC) Experimentally validated effector 203 IpaB_EvcA Unknown Mitochondrion Nucleus Complete SOPE_SALHO SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella houtenae Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete B7UR62_ECO27 T3SS secreted effector NleH homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 303 None Unknown Any other location Membrane Complete BOPA_BURM9 BopA Plays a role in mediating bacterial evasion from the host autophagic pathway Animals and Humans Burkholderia mallei (strain NCTC 10229) Experimentally validated effector 512 SicP-binding Unknown Mitochondrion Golgi Complete A1KWQ4_ECOLX NleA11 Unknown Animals and Humans Escherichia coli Experimentally validated effector 442 Gly-zipper_Omp Unknown Any other location Membrane Complete A2A0W7_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O157:H- Experimentally validated effector 384 EspF Unknown Mitochondrion Nucleus Complete B5R1Z8_SALEP SopE Unknown Animals and Humans Salmonella enteritidis PT4 (strain P125109) Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete Q5XL02_AERHY AopB Unknown Animals and Humans Aeromonas hydrophila Experimentally validated effector 395 SseC Unknown Any other location Cytoplasm, Complete C8TNU8_ECO26 EspF Unknown Animals and Humans Escherichia coli O26:H11 (strain 11368 / EHEC) Experimentally validated effector 207 EspF Unknown Mitochondrion Nucleus Complete YOPJ_YERPS YopJ Blocks the innate immune response by blocking cytokine production and inducing apoptosis in the infected cells. Inhibits the MAPK and NF-kappa-B signaling pathways by acetylating MAP2K1, MAP2K6 and probably also MAP2K3, MAP2K4 and I-kappa-B kinase on residues critical for their activation by phosphorylation, thus preventing it. Animals and Humans Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 288 YopJ Unknown Any other location Membrane Complete SOPE_SALTI SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella typhi Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete SSEL_SALPB Deubiquitinase SseL Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells. Animals and Humans Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) Experimentally validated effector 340 None Cytoplasm Any other location Cytoplasm Complete D0JM81_YERPD Secreted effector protein GN=yopM Unknown Rodents Yersinia pestis (strain D106004) Experimentally validated effector 430 TTSSLRR Unknown Any other location Secreted Complete Q4G4D1_EDWTA EseD Unknown Animals Edwardsiella tarda Experimentally validated effector 193 EspB(Enterobacterial EspB protein) Unknown Any other location Cytoplasm, Complete C8TWM3_ECO10 Map Unknown Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 203 IpaB_EvcA Unknown Mitochondrion Nucleus Complete B5R199_SALEP Secreted effector protein GN=sspH2 Unknown Animals and Humans Salmonella enteritidis PT4 (strain P125109) Experimentally validated effector 788 TTSSLRR; NEL Unknown Mitochondrion Cytoplasm Complete D2TI15_CITRI EspT Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 189 IpaB_EvcA Unknown Any other location Cytoplasm Complete PIPB2_SALCH pipB2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells. Animals and Humans Salmonella choleraesuis (strain SC-B67) Experimentally validated effector 350 Contains various tandem pentapeptide repeats in the C-terminal region. The pentapeptide motif is required to efficiently recruit kinesin-1. No position is completely conserved in these repeats, whose consensus sequence is A-[DN]-[FLM]-X-X. The C-terminal 38 amino acids residues, specifically, the C-terminal motif LFNEF, are required for peripheral localization of pipB2 and redistribution of lysosomal-associated membrane protein (LAMP). The N-terminal 225 amino acids residues are sufficient for type III translocation and association with Sifs and SCVs, but not accumulation in peripheral vesicles. Membrane Mitochondrion Membrane Complete A8R3Y1_ECOLX Translocated intimin receptor Tir Unknown Animals and Humans Escherichia coli Experimentally validated effector 568 Tir_receptor_N; Tir_receptor_M; Tir_receptor_C Unknown Any other location Nucleus Complete B5F8C9_SALA4 Secreted effector protein Unknown Animals and Humans Salmonella agona (strain SL483) Experimentally validated effector 336 Sif Unknown Any other location Cytoplasm Complete A4PDT7_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O41:H- Experimentally validated effector 203 EspF Unknown Mitochondrion Nucleus Complete SOPE_SALDU Guanine nucleotide exchange factor SopE Acts in concert with other proteins to mediate cellular responses leading to bacterial internalization. Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella dublin Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete A4PDU4_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26:NM Experimentally validated effector 344 EspF Unknown Mitochondrion Nucleus Complete C6UYI2_ECO5T Translocated type III secretion system effector Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 172 AvrPphF-ORF-2 Unknown Any other location Nucleus Complete SSPH1_SALT1 E3 ubiquitin-protein ligase sspH1 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Can ubiquitinate both ubiquitin and host PKN1. Down-modulates production of host proinflammatory cytokines by inhibiting NF-kappa-B-dependent gene expression, probably via interaction with PKN1. Animals and Humans Salmonella typhimurium (strain 14028s / SGSC 2262) Experimentally validated effector 700 The LRR (leucine-rich repeat) domain mediates interaction with host PKN1 and inhibition of NF-kappa-B-dependent gene expression. cytoplasm Any other location Cytoplasm Complete A4PDT8_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O154:H9 Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete A1KWQ2_ECOLX NleA9 Unknown Animals and Humans Escherichia coli Experimentally validated effector 441 None Unknown Any other location Cytoplasm Complete B5BAF1_SALPK Putative virulence determinant Unknown Animals and Humans Salmonella paratyphi A (strain AKU_12601) Experimentally validated effector 336 Sif Unknown Any other location Cytoplasm Complete A4PDT6_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O51:H- Experimentally validated effector 485 EspF Unknown Mitochondrion Nucleus Complete Q57P56_SALCH Translocated effector SifB Unknown Animals and Humans Salmonella choleraesuis (strain SC-B67) Experimentally validated effector 303 Sif Unknown Any other location Cytoplasm, Complete Q2F7Y9_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 290 EspF Unknown Mitochondrion Nucleus Complete A1JU68_YERE8 Yop type III secretion system effector protein Unknown Animals and Humans Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) Experimentally validated effector 367 TTSSLRR Unknown Any other location Secreted Complete P74988_YEREN Yop effector YopM Unknown Animals and Humans Yersinia enterocolitica Experimentally validated effector 367 TTSSLRR Unknown Any other location Secreted Complete D0JY05_YERP1 Secreted effector protein Unknown Rodents Yersinia pestis (strain D182038) Experimentally validated effector 430 TTSSLRR Unknown Any other location Secreted Complete A4PDV2_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26 Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete B4TIM3_SALHS SifB Unknown Animals and Humans Salmonella heidelberg (strain SL476) Experimentally validated effector 316 Sif Unknown Mitochondrion Cytoplasm Complete C8UFJ4_ECO1A T3SS secreted effector EspG Unknown Animals and Humans Escherichia coli O111:H- (strain 11128 / EHEC) Experimentally validated effector 398 EspG Unknown Any other location Membrane Complete Q5XMK7_CITRO NleE Unknown Rodents Citrobacter Rodentsium Experimentally validated effector 230 UAE_UbL(Ubiquitin/SUMO-activating enzyme ubiquitin-like domain) Unknown Any other location Cytoplasm Complete C8TNT4_ECO26 T3SS secreted effector EspH Unknown Animals and Humans Escherichia coli O26:H11 (strain 11368 / EHEC) Experimentally validated effector 171 Xpo1(Exportin 1-like protein) Unknown Mitochondrion Cytoplasm Complete BOPA_BURP0 Effector protein BopA Plays a role in mediating bacterial evasion from the host autophagic pathway. Animals and Humans Burkholderia pseudomallei (strain 1106a) Experimentally validated effector 512 SicP-binding Unknown Mitochondrion Golgi Complete D0ZDK9_EDWTE Type III secretion system effector protein D Unknown Animals Edwardsiella tarda (strain EIB202) Experimentally validated effector 193 EspB Unknown Any other location Cytoplasm Complete IPA4_SHIFL Probable E3 ubiquitin-protein ligase ipaH4.5 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Animals and Humans Shigella flexneri Experimentally validated effector 574 The LRR (leucine-rich repeat) domain forms a slightly curved solenoid and may mediate interaction with target proteins. cytoplasm Mitochondrion Nucleus Complete SIPA_SALTS Cell invasion protein sipA Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F-actin destabilizing proteins. Potentiates SipC activity; both are required for an efficient bacterial internalization. In vitro, forms a complex with host cell protein T-plastin increasing actin bundling. It inhibits ADF/cofilin-directed depolymerization both by preventing binding of ADF and cofilin and by displacing them from F-actin. Also protects F-actin from gelsolin-directed severing and reanneals gelsolin-severed F-actin fragments. Animals and Humans Salmonella typhimurium (strain SL1344) Experimentally validated effector 685 SipA(Salmonella invasion protein A) Unknown Any other location Cytoplasm Complete A4PHQ3_ECOLX Translocated intimin receptor Tir Unknown Animals and Humans Escherichia coli O104:H12 Experimentally validated effector 550 Tir_receptor_N; Tir_receptor_M; Tir_receptor_C Unknown Any other location Nucleus Complete A4PHQ4_ECOLX Translocated intimin receptor Tir Unknown Animals and Humans Escherichia coli NT:H19 Experimentally validated effector 572 Tir_receptor_N; Tir_receptor_M; Tir_receptor_C Unknown Any other location Nucleus Complete D2TZ34_9ENTR Type III secretion effector protein SipB Unknown Nasonia vitripennis and wasps Arsenophonus nasoniae (son-killer infecting Nasonia vitripennis) Experimentally validated effector 666 SseC Unknown Any other location Cytoplasm Complete A2A0X8_ECOLX Type III secreted effector protein Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete SOPE_SALGL Guanine nucleotide exchange factor SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Aves Salmonella gallinarum Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete A1KWQ3_ECOLX NleA10 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 413 None Unknown Any other location Cytoplasm Complete SPTP_SALTI Secreted effector protein SptP Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear. Animals and Humans Salmonella typhi Experimentally validated effector 543 SicP-binding; YopE; Y_phosphatase cytoplasm Any other location Nucleus Complete A9ZNG6_ECOLX Non-LEE-encoded effector NleH Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 293 YrbL-PhoP_reg Unknown Mitochondrion Membrane Complete D2TKE1_CITRI T3SS effector protein EspB Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 321 EspB Unknown Any other location Cytoplasm Complete B4TW50_SALSV SifB Unknown Animals and Humans Salmonella schwarzengrund (strain CVM19633) Experimentally validated effector 316 Sif Unknown Mitochondrion Nucleus Complete D2TKE2_CITRI T3SS translocator protein EspD Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 380 SseC Unknown Any other location Cytoplasm Complete PIPB2_SALTI Secreted effector protein pipB2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells. Animals and Humans Salmonella typhi Experimentally validated effector 350 Contains various tandem pentapeptide repeats in the C-terminal region. The pentapeptide motif is required to efficiently recruit kinesin-1. No position is completely conserved in these repeats, whose consensus sequence is A-[DN]-[FLM]-X-X. The C-terminal 38 amino acids residues are required for peripheral localization of pipB2 and redistribution of lysosomal-associated membrane protein (LAMP). The N-terminal 225 amino acids residues are sufficient for type III translocation and association with Sifs and SCVs, but not accumulation in peripheral vesicles. Membrane Mitochondrion Membrane Complete C8UMB1_ECO1A T3SS secreted effector TccP2 Unknown Animals and Humans Escherichia coli O111:H- (strain 11128 / EHEC) Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete SOPE_SALET Guanine nucleotide exchange factor SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella enterica I Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete C6V2C9_ECO5T Non-LEE-encoded type III secreted effector Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 330 Peptidase_M85 Unknown Any other location Membrane Complete A6M3U5_YERPE Leucine-rich 15-repeat translocated effector protein Unknown Animals and Humans Yersinia pestis CA88-4125 Experimentally validated effector 409 TTSSLRR Unknown Any other location Secreted Complete A2A0Z2_ECOLX Type III secreted effector protein Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete IPA3_SHIFL E3 ubiquitin-protein ligase ipaH3 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Synthesizes a Lys-48-linked ubiquitin chain, which requires non-covalent binding between ubiquitin and the host ubiquitin-conjugating enzyme UBE2D1. Animals and Humans Shigella flexneri Experimentally validated effector 571 The LRR (leucine-rich repeat) domain forms a slightly curved solenoid and may mediate interaction with target proteins. cytoplasm Any other location Nucleus Complete D2TJZ3_CITRI T3SS effector protein EspS Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 291 None Unknown Any other location Membrane Complete Q1W4Y8_PSEAI Type three secretion system effector protein GN=exoU Unknown Animals and Humans Pseudomonas aeruginosa Experimentally validated effector 687 Patatin Unknown Any other location Cytoplasm Complete A9ZNE5_ECOLX Non-LEE-encoded effector NleH Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 293 YrbL-PhoP_reg Unknown Any other location Membrane Complete A2A0X2_ECO57 Type III secreted effector protein Unknown Animals and Humans Escherichia coli O157:H7 Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete C6UYL9_ECO5T Type III secreted effector protein Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 203 IpaB_EvcA Unknown Mitochondrion Cytoplasm Complete D2TZV2_9ENTR Type III secreted effector protein YopN,Yop4b,LcrE,InvE Unknown Nasonia vitripennis and wasps Arsenophonus nasoniae (son-killer infecting Nasonia vitripennis) Experimentally validated effector 326 HrpJ Unknown Any other location Cytoplasm Complete D2TKD7_CITRI T3SS effector protein EspF Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 301 Apolipoprotein EspF Unknown Mitochondrion Nucleus Complete C8TN38_ECO26 T3SS secreted effector TccP2 Unknown Animals and Humans Escherichia coli O26:H11 (strain 11368 / EHEC) Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete OSPF_SHIDS Phosphothreonine lyase OspF Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacteriums ability to disseminate and multiply within the host Animals and Humans Shigella dysenteriae serotype 1 (strain Sd197) Experimentally validated effector 239 VRP3(Salmonella virulence-associated 28kDa protein) Nucleus Any other location Cytoplasm Complete PIPB_SALTY Secreted effector protein PipB Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Does not appear to be required for the formation or the maintenance of either Salmonella-containing vacuole (SCV) or the Salmonella-induced filaments (Sifs). Not required for intracellular replication in phagocytic cells Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 291 Pentapeptide Membrane Any other location Membrane Complete C6USQ1_ECO5T Non-LEE-encoded type III secreted effector Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 441 None Unknown Any other location Membrane Complete B8ZYA3_ECOLX Type III secretion system, translocated effector, LEE associated GN=sepZ Unknown Animals and Humans Escherichia coli Experimentally validated effector 98 SepZ Unknown Any other location Membrane Complete A4PDV3_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26 Experimentally validated effector 344 EspF Unknown Mitochondrion Nucleus Complete SOPE_SALHA Guanine nucleotide exchange factor SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella hadar Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete B3Y0U1_ECO11 T3SS secreted effector NleF-homolog Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 189 DUF4468(Domain of unknown function (DUF4468) with TBP-like fold) Unknown Any other location Cytoplasm Complete C6V2C8_ECO5T Non-LEE-encoded type III secreted effector GN=nleB1 Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 326 None Unknown Any other location Cytoplasm Complete B7ULW8_ECO27 T3SS secreted effector EspJ homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 217 AvrPphF-ORF-2 DUF3319 Unknown Any other location Mitochondrion Complete SIFB_SALTY Secreted effector protein SifB Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 316 Sif Cytoplasm Mitochondrion Nucleus Complete SSEJ_SALTY Secreted effector protein SseJ Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required for endosomal tubulation and negatively regulates the formation of Salmonella-induced filaments (Sifs) in epithelial cells. Has both deacylase and esterification activities in vitro, but esterification is probably the dominant activity in host cells. Significantly contributes to cholesterol esterification, which reduces cellular cholesterol in cells and abrogates the ability of SifA to associate with cholesterol and LAMP-1 vesicles. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 408 Sif; Lipase_GDSL cytoplasm Any other location Cytoplasm Complete Q4ACE6_EDWTA Type III secretion system effector protein D Unknown Animals Edwardsiella tarda Experimentally validated effector 126 DnaJ-X; HOOK Unknown Any other location Cytoplasm Fragment A9ZNF2_ECOLX Non-LEE-encoded effector EspJ Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 217 AvrPphF-ORF-2; DUF3319 Unknown Any other location Mitochondrion Complete B8ZYN7_ECOLX Type III secretion system, translocated effector, LEE associated Unknown Animals and Humans Escherichia coli Experimentally validated effector 98 SepZ Unknown Any other location Membrane Complete A6YCJ6_AERHY AexT Unknown Animals and Humans Aeromonas hydrophila Experimentally validated effector 428 YopE Unknown Any other location Cytoplasm Complete A2A0Z6_ECOLX Type III secreted effector protein Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete D2TKE9_CITRI T3SS effector protein Map Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 203 IpaB_EvcA Unknown Mitochondrion Cytoplasm Complete C8UFL8_ECO1A T3SS secreted effector EspZ Unknown Animals and Humans Escherichia coli O111:H- (strain 11128 / EHEC) Experimentally validated effector 98 SepZ Unknown Any other location Membrane Complete C6UYP6_ECO5T LEE-encoded type III secreted effector Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 398 EspG Unknown Any other location Membrane Complete A1KWP6_ECOLX NleA5 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 439 None Unknown Any other location Membrane Complete A9ZNG7_ECOLX Non-LEE-encoded effector NleG Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 191 DUF1076 Unknown Any other location Nucleus Complete A1KWQ0_ECOLX NleA8-1 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 440 None Unknown Any other location Membrane Complete O34208_PSEAI ExoU Unknown Animals Pseudomonas aeruginosa Experimentally validated effector 687 Patatin Unknown Any other location Cytoplasm Complete A9ZNE9_ECOLX Non-LEE-encoded effector NleG Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 191 DUF1076 Unknown Any other location Nucleus Complete D2TKD5_CITRI T3SS effector protein EspG Unknown Rodents Citrobacter Rodentsium (strain ICC168) (Citrobacter freundii biotype 4280) Experimentally validated effector 398 EspG Unknown Any other location Cytoplasm, Complete A1KWP3_ECOLX NleA2 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 413 None Unknown Any other location Cytoplasm Complete D0ZI08_SALT1 Secreted effector protein Unknown Animals and Humans Salmonella typhimurium (strain 14028s / SGSC 2262) Experimentally validated effector 316 Sif Unknown Mitochondrion Nucleus Complete A4PDT9_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli NT:H19 Experimentally validated effector 391 EspF Unknown Mitochondrion Nucleus Complete A4PDU3_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli NT:H19 Experimentally validated effector 344 EspF Unknown Mitochondrion Nucleus Complete STEA_SALTY Secreted effector protein SteA Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 210 None cytoplasm Mitochondrion Cytoplasm Complete BOPA_BURP1 Effector protein BopA Plays a role in mediating bacterial evasion from the host autophagic pathway. Animals and Humans Burkholderia pseudomallei (strain 1710b) Experimentally validated effector 512 SicP-binding Unknown Any other location Golgi, Complete B4TTJ6_SALSV Secreted effector protein Unknown Animals and Humans Salmonella schwarzengrund (strain CVM19633) Experimentally validated effector 336 Sif Unknown Any other location Cytoplasm Complete STEC_SALTY Secreted effector kinase SteC Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase, which is required for SPI-2 TTSS-dependent F-actin meshwork formation in infected host cells. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 457 None cytoplasm Any other location Cytoplasm Complete OSPF_SHIDY Phosphothreonine lyase OspF Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacteriums ability to disseminate and multiply within the host. Animals and Humans Shigella dysenteriae Experimentally validated effector 170 VRP3 nucleus Any other location Endoplasmic Fragment C8TWN2_ECO10 T3SS secreted effector EspZ Unknown Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 98 SepZ Unknown Any other location Membrane Complete B3Y094_ECO11 T3SS secreted effector NleB-homolog Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 326 None Unknown Any other location Cytoplasm Complete C8TWM5_ECO10 T3SS secreted effector EspH Unknown Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 171 Xpo1(Exportin 1-like protein) Unknown Mitochondrion Cytoplasm Complete PIPB2_SALTY Secreted effector protein pipB2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 350 Contains various tandem pentapeptide repeats in the C-terminal region. The pentapeptide motif is required to efficiently recruit kinesin-1. No position is completely conserved in these repeats, whose consensus sequence is A-[DN]-[FLM]-X-X. The C-terminal 38 amino acids residues, specifically, the C-terminal motif LFNEF, are required for peripheral localization of pipB2 and redistribution of lysosomal-associated membrane protein (LAMP). The N-terminal 225 amino acids residues are sufficient for type III translocation and association with Sifs and SCVs, but not accumulation in peripheral vesicles. membrane Any other location Membrane Complete SOPB_SALDZ Inositol phosphate phosphatase SopB Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell. Animals and Humans Salmonella diarizonae Experimentally validated effector 416 Contains the consensus sequence Cys-X(5)-Arg characteristic of Mg-independent phosphatases. Unknown Any other location Cytoplasm Fragment A1KWP7_ECOLX NleA6-1 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 458 None Unknown Any other location Mitochondrion Complete C9XA81_SALTD Secreted effector protein Unknown Animals and Humans Salmonella typhimurium (strain D23580) Experimentally validated effector 788 TTSSLRR; NEL Unknown Mitochondrion Cytoplasm Complete A4PDU6_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26:H11 Experimentally validated effector 344 EspF Unknown Mitochondrion Nucleus Complete A9ZNG8_ECOLX Non-LEE-encoded effector NleA Unknown Animals and Humans Escherichia coli O103:H2 Experimentally validated effector 412 None Unknown Any other location Cytoplasm Complete A4PDU7_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O111:H19 Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete B5FUU4_SALDC Secreted effector protein Unknown Animals and Humans Salmonella dublin (strain CT_02021853) Experimentally validated effector 316 Sif Unknown Mitochondrion Nucleus Complete B8ZYG2_ECOLX Type III secretion system, translocated effector protein, LEE associated Unknown Animals and Humans Escherichia coli Experimentally validated effector 177 None Unknown Mitochondrion Membrane Complete C6UYM1_ECO5T LEE-encoded type III secreted effector Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 168 None Unknown Mitochondrion Membrane Complete B3Y0A5_ECO11 T3SS secreted effector, TccP2 Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete A1KWP9_ECOLX NleA7 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 414 DUF4331 Unknown Any other location Cytoplasm Complete A4PDU2_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O109:H9 Experimentally validated effector 485 EspF Unknown Mitochondrion Nucleus Complete A1KWQ1_ECOLX NleA8-2 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 440 None Unknown Any other location Membrane Complete OSPF_SHISS Phosphothreonine lyase OspF Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacteriums ability to disseminate and multiply within the host. Animals and Humans Shigella sonnei (strain Ss046) Experimentally validated effector 239 VRP3(Salmonella virulence-associated 28kDa protein) Nucleus Any other location Cytoplasm Complete SIPB_SALTY Cell invasion protein SipB Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE. Animals and Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 593 SipB membrane integration requires both hydrophobic domains and the helical C-terminal region. Membrane Any other location Cytoplasm Complete A1KWP2_ECOLX NleA1 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 413 None Unknown Any other location Cytoplasm Complete Q2F7Z0_ECOLX Translocated intimin receptor Unknown Animals and Humans Escherichia coli Experimentally validated effector 549 Tir_receptor_N; Tir_receptor_M; Tir_receptor_C Unknown Any other location Nucleus Complete B3Y095_ECO11 T3SS secreted effector NleH-homolog Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 293 YrbL-PhoP_reg Unknown Any other location Membrane Complete A4PDU9_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O115:K+ Experimentally validated effector 203 EspF Unknown Mitochondrion Nucleus Complete B3Y1A0_ECO11 T3SS secreted effector EspM-homolog Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 194 IpaB_EvcA Unknown Any other location Nucleus Complete C8UFJ7_ECO1A T3SS secreted effector EspF Unknown Animals and Humans Escherichia coli O111:H- (strain 11128 / EHEC) Experimentally validated effector 262 EspF Unknown Mitochondrion Nucleus Complete SOPE_SALEE Guanine nucleotide exchange factor SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella enterica VII Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete SSEL_SALTI Deubiquitinase SseL Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells. Animals and Humans Salmonella typhi Experimentally validated effector 340 None Cytoplasm Any other location Cytoplasm Complete C8TWL1_ECO10 T3SS secreted effector EspF Unknown Animals and Humans Escherichia coli O103:H2 (strain 12009 / EHEC) Experimentally validated effector 294 EspF Unknown Mitochondrion Nucleus Complete B4T5Z0_SALNS Secreted effector protein Unknown Animals and Humans Salmonella newport (strain SL254) Experimentally validated effector 316 Sif Unknown Mitochondrion Cytoplasm Complete SIPA_SALTI Cell invasion protein SipA Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F-actin destabilizing proteins. Potentiates SipC activity; both are required for an efficient bacterial internalization. Animals and Humans Salmonella typhi Experimentally validated effector 685 SipA Unknown Any other location Nucleus Complete Q699Q8_AERHY AopB Unknown Animals and Humans Aeromonas hydrophila Experimentally validated effector 390 SseC Unknown Any other location Mitochondrion Complete A2A0W5_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O157:H- Experimentally validated effector 337 EspF Unknown Mitochondrion Nucleus Complete Q663L9_YERPS YopM putative targeted effector protein Unknown Animals and Humans Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 550 TTSSLRR Unknown Any other location Secreted Complete B5QTK1_SALEP Putative virulence effector protein Unknown Animals and Humans Salmonella enteritidis PT4 (strain P125109) Experimentally validated effector 316 Sif Unknown Mitochondrion Cytoplasm Complete OSPF_SHIBO Phosphothreonine lyase OspF Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacteriums ability to disseminate and multiply within the host. Animals and Humans Shigella boydii Experimentally validated effector 170 VRP3 Nucleus Any other location Endoplasmic Fragment Q6TLM0_AERHY AopB Unknown Animals and Humans Aeromonas hydrophila Experimentally validated effector 347 SseC Unknown Any other location Mitochondrion Complete A4PDV0_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O26:H11:K60 Experimentally validated effector 250 EspF Unknown Mitochondrion Nucleus Complete A4PCI6_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O111:H2 Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete C6USR0_ECO5T Non-LEE-encoded type III secreted effector Unknown Animals and Humans Escherichia coli O157:H7 (strain TW14359 / EHEC) Experimentally validated effector 196 IpaB_EvcA Unknown Any other location Nucleus, Complete A9ZNF7_ECO11 Non-LEE-encoded effector NleH Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 293 YrbL-PhoP_reg Unknown Any other location Membrane Complete Q93KU8_YEREN Yop effector YopM Unknown Animals and Humans Yersinia enterocolitica Experimentally validated effector 367 TTSSLRR Unknown Any other location Secreted Complete SOPE_SALTM Guanine nucleotide exchange factor SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Also activates MAPK8, indicating that it is capable of stimulating signaling pathways that can lead to nuclear responses. Chaperone InvB is required for secretion and translocation of SopE. Animals and Humans Salmonella typhimurium Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete D2TZ31_9ENTR Type III secretion effector protein SipA Unknown Nasonia vitripennis and wasps Arsenophonus nasoniae (son-killer infecting Nasonia vitripennis) Experimentally validated effector 373 Rsbr_N DUF4478 Unknown Any other location Nucleus, Complete SOPB_SALHO Inositol phosphate phosphatase SopB Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell. Animals and Humans Salmonella houtenae Experimentally validated effector 416 IpgD Unknown Any other location Nucleus Fragment Q6R8C3_SODGL YspA Unknown Insects Sodalis glossinidius Experimentally validated effector 672 None Unknown Any other location Nucleus Complete A4PDV5_ECO11 Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete SIPB_SALDU Cell invasion protein SipB Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE. Animals and Humans Salmonella dublin Experimentally validated effector 593 SipB membrane integration requires both hydrophobic domains and the helical C-terminal region. Host cell membrane Any other location Cytoplasm Complete A2A0X5_ECOLX Type III secreted effector protein Unknown Animals and Humans Escherichia coli O157:H- Experimentally validated effector 438 EspF Unknown Mitochondrion Nucleus Complete Q27RI0_AERS4 AopO Unknown Salmonid Aeromonas salmonicida (strain A449) Experimentally validated effector 728 Pkinase Rac1 Unknown Any other location Cytoplasm Complete A1KWP4_ECOLX NleA3 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 439 None Unknown Any other location Cytoplasm Complete OSPF_SHIBS Phosphothreonine lyase OspF Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases p38, phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacteriums ability to disseminate and multiply within the host. Animals and Humans Shigella boydii serotype 4 (strain Sb227) Experimentally validated effector 239 VRP3(Salmonella virulence-associated 28kDa protein) nucleus Any other location Cytoplasm Complete B3Y098_ECO11 T3SS secreted effector NleA-homolog Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 412 None Unknown Any other location Cytoplasm Complete SSEL_SALAR Deubiquitinase SseL Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells. Animals and Humans Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) Experimentally validated effector 340 None cytoplasm Any other location Endoplasmic Complete SIPB_SALTI Cell invasion protein SipB Required for entry into the host cell through presentation or delivery of SipC at the host cell plasma membrane. Along with SipC, is necessary for the transfer of other effector proteins into the host cell. Induces macrophage apoptosis either by binding and activating the proapoptotic enzyme caspase-1 (caspase-1 dependent), resulting in the release of interleukin-1 beta active form, or by disrupting mitochondria and inducing autophagy (caspase-1 independent). The former is dependent of its membrane-fusion activity. The SipBC complex, in association with its chaperone SicA, is regulated by binding of InvE. Animals and Humans Salmonella typhi Experimentally validated effector 593 SipB membrane integration requires both hydrophobic domains and the helical C-terminal region Host cell membrane Any other location Cytoplasm Complete OSPF_SHIFL Phosphothreonine lyase OspF Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacteriums ability to disseminate and multiply within the host. Animals and Humans Shigella flexneri Experimentally validated effector 239 VRP3 nucleus Any other location Cytoplasm Complete B8ZY96_ECOLX Type III secretion system, translocated effector protein, LEE associated Unknown Animals and Humans Escherichia coli Experimentally validated effector 177 None Unknown Mitochondrion Membrane Complete B5F5S8_SALA4 Secreted effector protein Unknown Animals and Humans Salmonella agona (strain SL483) Experimentally validated effector 316 Sif Unknown Mitochondrion Cytoplasm Complete A4PDU1_ECOLX Tir-cytoskeleton coupling protein Unknown Animals and Humans Escherichia coli O13:H11 Experimentally validated effector 297 EspF Unknown Mitochondrion Nucleus Complete Q4G4C8_EDWTA EseB Unknown Animals Edwardsiella tarda Experimentally validated effector 198 EspA Unknown Any other location Cytoplasm Complete SSEL_SALCH Deubiquitinase SseL Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells. Animals and Humans Salmonella choleraesuis (strain SC-B67) Experimentally validated effector 340 None cytoplasm Any other location Cytoplasm Complete PIPB2_SALPA Secreted effector protein pipB2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells. Animals and Humans Salmonella paratyphi A (strain ATCC 9150 / SARB42) Experimentally validated effector 350 Contains various tandem pentapeptide repeats in the C-terminal region. The pentapeptide motif is required to efficiently recruit kinesin-1. No position is completely conserved in these repeats, whose consensus sequence is A-[DN]-[FLM]-X-X. The C-terminal 38 amino acids residues, specifically, the C-terminal motif LFNEF, are required for peripheral localization of pipB2 and redistribution of lysosomal-associated membrane protein (LAMP). The N-terminal 225 amino acids residues are sufficient for type III translocation and association with Sifs and SCVs, but not accumulation in peripheral vesicles. membrane Mitochondrion Membrane Complete SSPH2_SALT1 E3 ubiquitin-protein ligase sspH2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with hosts ubiquitination pathway. Contributes to virulence in calves. Animals and Humans Salmonella typhimurium (strain 14028s / SGSC 2262) Experimentally validated effector 788 The LRR (leucine-rich repeat) domain forms a slightly curved solenoid and may mediate interaction with target proteins. It is involved in autoinhibition of the enzyme activity by interacting with the catalytic domain. Host apical cell membrane Mitochondrion Cytoplasm Complete SOPE_SALPA Guanine nucleotide exchange factor SopE Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells. Animals and Humans Salmonella paratyphi A (strain ATCC 9150 / SARB42) Experimentally validated effector 240 SecIII_SopE_N; SopE_GEF Unknown Any other location Nucleus Complete A9R9G8_YERPG Effector protein YopM Unknown Rodents Yersinia pestis bv. Antiqua (strain Angola) Experimentally validated effector 388 TTSSLRR Unknown Any other location Secreted Complete A1KWP5_ECOLX NleA4 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 345 None Unknown Any other location Cytoplasm Complete SIPA_SALEN Cell invasion protein SipA Actin-binding protein that interferes with host cell actin cytoskeleton. It stimulates actin polymerization and counteracts F-actin destabilizing proteins. Potentiates SipC activity; both are required for an efficient bacterial internalization. Animals and Humans Salmonella enteritidis Experimentally validated effector 685 SipA Unknown Any other location Cytoplasm Complete B7UR60_ECO27 T3SS secreted effector NleA/EspI homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 440 None Unknown Any other location Membrane Complete SSEL_SALPA Deubiquitinase SseL Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells. Animals and Humans Salmonella paratyphi A (strain ATCC 9150 / SARB42) Experimentally validated effector 340 None cytoplasm Any other location Cytoplasm Complete ICSB_SHIFL Virulence protein IcsB Virulence-associated effector required at the post-invasion stage of Shigella pathogenicity. Animals and Humans Shigella flexneri Experimentally validated effector 494 SicP-binding Unknown Any other location Cytoplasm Complete SPTP_SALPA Secreted effector protein SptP Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear. Animals and Humans Salmonella paratyphi A (strain ATCC 9150 / SARB42) Experimentally validated effector 543 SicP-binding; YopE Y_phosphatase cytoplasm Any other location Nucleus Complete STEA_SALT1 Secreted effector protein SteA Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Could be required for passage of bacteria from the peritoneal cavity into the spleen, for survival and replication within host cells, or for avoiding host immune response. Animals and Humans Salmonella typhimurium (strain 14028s / SGSC 2262) Experimentally validated effector 210 None cytoplasm Mitochondrion Cytoplasm Complete Q5PMJ9_SALPA Putative virulence determinant GN=sifA Unknown Animals and Humans Salmonella paratyphi A (strain ATCC 9150 / SARB42) Experimentally validated effector 336 Sif Unknown Any other location Cytoplasm Complete A1KWP8_ECOLX NleA6-2 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 462 None Unknown Any other location Cytoplasm, Complete A9MYP6_SALPB Uncharacterized protein GN=SPAB_01680 Unknown Animals and Humans Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) Experimentally validated effector 316 Sif Unknown Mitochondrion Nucleus Complete A9ZNG0_ECO11 Non-LEE-encoded effector EspJ Unknown Animals and Humans Escherichia coli O111:H- Experimentally validated effector 217 AvrPphF-ORF-2 DUF3319 Unknown Any other location Mitochondrion Complete YOPT_YEREN Cysteine protease YopT Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the Humans small GTPase RhoA/ARHA, a regulator of cytoskeleton. Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell Humans and Animals Yersinia enterocolitica Experimentally validated effector 322 Peptidase_C58 Cytoplasm Any other location Secreted Complete O84625_CHLTR Putative uncharacterized protein GN=CT_620 Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 838 Effector from type III secretion system Unknown Any other location Secreted Complete Q3KMQ0_CHLTA Inclusion membrane protein A Unknown Humans Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) Experimentally validated effector 273 IncA protein Unknown Secretory pathway Secreted Complete O84235_CHLTR Inclusion Membrane Protein B Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 115 1GPI biosynthesis protein family Pig-F 2Orbivirus NS3 Unknown Secretory pathway Membrane Complete Q9Z8P7_CHLPN Inclusion Membrane Protein B Unknown Humans Chlamydia pneumoniae (Chlamydophila pneumoniae) Experimentally validated effector 176 ABC2_membrane_4(ABC-2 family transporter protein) Unknown Any other location Membrane Complete O84236_CHLTR Inclusion Membrane Protein C Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 178 Fatty acid desaturase Unknown Any other location Membrane Complete Q9Z8P6_CHLPN Inclusion Membrane Protein C Unknown Humans Chlamydia pneumoniae Experimentally validated effector 203 DUF1469 Unknown Any other location Membrane Complete INCD_CHLTR Inclusion membrane protein D Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion. Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 141 IncA protein Membrane Any other location Membrane Complete INCE_CHLTR Inclusion membrane protein E Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion. Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 132 IncA protein Membrane Any other location Membrane Complete INCF_CHLTR Inclusion membrane protein F Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 104 None Membrane Any other location Membrane Complete Q9Z9F5_CHLPN Putative uncharacterized protein Unknown Humans Chlamydia pneumoniae Experimentally validated effector 288 Cytochrome b(N-terminal)/b6/petB Unknown Secretory pathway Nucleus Complete Q9Z7W9_CHLPN CPj0585 protein Unknown Humans Chlamydia pneumoniae Experimentally validated effector 651 IncA protein Unknown Any other location Cytoplasm Complete C5IZN1_VIBCL VopF VopF is a contributory factor to the intestinal colonization of type III secretion system-positive, non-O1, non-O139 Vibrio cholerae strains. Humans Vibrio cholerae Experimentally validated effector 530 WH2 motif Unknown Any other location Nucleus Complete O84700_CHLTR GN=CT_694 Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 323 None Unknown Any other location Nucleus Complete C4PPW4_CHLTJ Putative type III secretion system membrane protein GN=copB Unknown Humans Chlamydia trachomatis serovar B (strain Jali20/OT) Experimentally validated effector 487 Secretion system effector C (SseC) like family membrane Any other location Nucleus Complete O84869_CHLTR GN=CT_861 Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 506 Plasmodium_Vir Unknown Any other location Cytoplasm Complete Q9Z8N0_CHLPN CPj0308 Unknown Humans Chlamydia pneumoniae (Chlamydophila pneumoniae) Experimentally validated effector 121 DUF3611; SdpI; DUF1469; IncA; DUF1304; DUF1634 Unknown Secretory pathway Membrane Complete C4PLU2_CHLTZ Low calcium response protein E Unknown Humans Chlamydia trachomatis serovar B (strain TZ1A828/OT) Experimentally validated effector 421 HrpJ Unknown Any other location Nucleus Complete B0B8P9_CHLT2 Putative serine/threonine-protein kinase GN=pkn5 Unknown Humans Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) Experimentally validated effector 490 Pkinase Unknown Mitochondrion Cytoplasm Complete C4PQ60_CHLTJ Putative serine/threonine-protein kinase Unknown Humans Chlamydia trachomatis serovar B (strain Jali20/OT) Experimentally validated effector 490 Pkinase Unknown Mitochondrion Cytoplasm Complete A0FKE4_9GAMM AexT Unknown Humans Aeromonas veronii Experimentally validated effector 453 YopE(Yersinia virulence determinant) (YopE); ADPrib_exo_Tox(ADP-ribosyltransferase exoenzyme) Unknown Any other location Cytoplasm Complete C4PNI4_CHLTZ Putative serine/threonine-protein kinase (TTSS effector protein) Unknown Humans Chlamydia trachomatis serovar B (strain TZ1A828/OT) Experimentally validated effector 490 Pkinase Unknown Mitochondrion Cytoplasm Complete B0BB76_CHLTB Low calcium response protein E (TTSS effector protein) Unknown Humans Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis) Experimentally validated effector 421 HrpJ Unknown Any other location Cytoplasm Complete A0FKE5_9GAMM AexU Unknown Humans Aeromonas veronii Experimentally validated effector 512 YopE Unknown Any other location Nucleus Complete D3UTQ1_CHLTS Low calcium response protein E (TTSS effector protein) Unknown Humans Chlamydia trachomatis serovar E (strain Sweden2) Experimentally validated effector 421 HrpJ Unknown Any other location Cytoplasm, Complete C4PP99_CHLTJ Low calcium response protein E (TTSS effector protein) Unknown Humans Chlamydia trachomatis serovar B (strain Jali20/OT) Experimentally validated effector 421 HrpJ Unknown Any other location Nucleus Complete B0B9J7_CHLT2 Low calcium response protein E (TTSS effector protein) Unknown Humans Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) Experimentally validated effector 421 HrpJ Unknown Any other location Nucleus Complete H6UWS2_XANOR T3SS effector protein XopR The effector play a role in bacterial virulence by suppressing basal defense responses in Plantss Rice Xanthomonas oryzae pv. oryzae Experimentally validated effector 437 None Unknown Chloroplast Nucleus Complete Q2AC60_9BURK HrpY Unknown Rice Acidovorax avenae subsp. avenae Experimentally validated effector 389 None Unknown Any other location Nucleus Complete D8P315_RALSL Type III effector AWR4 Unknown Plants Ralstonia solanacearum CFBP2957 Experimentally validated effector 510 Peptidase family M20/M25/M40 Peptidase dimerisation domain Unknown Mitochondrion Chloroplast Complete D8P4R3_RALSL AWR5 type III effector protein Unknown Plants Ralstonia solanacearum CFBP2957 Experimentally validated effector 1231 None Unknown Chloroplast Cell,wall,Chloroplast,Cytoplasm,Nucleus,Peroxisome Complete D8P729_RALSL Type III effector protein AWR2 Unknown Plants Ralstonia solanacearum CFBP2957 Experimentally validated effector 1084 None Unknown Mitochondrion Chloroplast,Nucleus Complete Q8XTK9_RALSO Type III effector protein awr1 Unknown Plants Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) Experimentally validated effector 1127 None Unknown Chloroplast Chloroplast,Nucleus Complete D8P480_RALSL Putative type III effector, AWR3 Unknown Plants Ralstonia solanacearum CFBP2957 Experimentally validated effector 1240 None Unknown Chloroplast Chloroplast,Nucleus Complete AVRB_PSESG Avirulence protein B Unknown Plants Pseudomonas syringae pv. glycinea Experimentally validated effector 321 AvrB_AvrC:Avirulence protein Unknown Chloroplast Chloroplast,Nucleus Complete HOPM1_PSESM Effector protein HopM1 Involved in the suppression of basal resistance and promotion of disease symptoms in Plantss. Mediates the ubiquitination and degradation, via the host proteasome, of a low-abundance immunity-associated protein in Arabidopsis thaliana. May be involved in the inhibition of a host vesicle trafficking pathway. Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 712 None Host membrane Any other location Nucleus Complete Q888Y7_PSESM HopQ1-1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 447 Inosine-uridine preferring nucleoside hydrolase Unknown Chloroplast Chloroplast,Nucleus Complete Q4ZYH0_PSEU2 AvrRpm1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 228 None Unknown Any other location Nucleus Complete Q886L1_PSESM HopAF1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 284 None Unknown Chloroplast Nucleus Complete Q88BF6_PSESM HopY1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 287 HrpA pilus formation protein Unknown Chloroplast Nucleus Complete Q889A9_PSESM HopAJ1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 413 HopAJ1 has an MLTB domain (COG2951, membrane-bound lytic murein transglycosylase B) and a PGB domain (PF01471, peptidoglycan binding domain 1) Unknown Secretory pathway Cell,wall Complete Q87V79_PSESM HopAN1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 404 Protein of unknown function, DUF1537 Unknown Any other location Chloroplast,Cytoplasm Complete Q882F0_PSESM HopP1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 324 Transglycosylase SLT domain Unknown Chloroplast Cell Complete Q8RP03_PSEYM HopPtoA1Pma Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 484 None Unknown Chloroplast Mitochondrion Complete Q888Y1_PSESM HopR1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 1957 None Unknown Chloroplast Chloroplast,Nucleus Complete Q87W07_PSESM HopI1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 488 DnaJ domain Unknown Chloroplast Golgi,apparatus,Nucleus Complete HRMA_PSESY HrmA Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 375 None Unknown Any other location Cytoplasm Complete Q87WF7_PSESM HopT1-2 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 389 None Unknown Any other location Chloroplast Complete Q87X57_PSESM HopE1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 211 None Unknown Any other location Nucleus Complete Q87W42_PSESM HopG1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 493 None Unknown Chloroplast Nucleus Complete Q88A09_PSESM HopH1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete Q881L7_PSESM HopL1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 899 Virul_Fac Unknown Any other location Chloroplast,Cytoplasm Complete Q9K2L5_PSESH ORF2 Unknown Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 204 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete Q87W46_PSESM HopV1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 390 Peptidase_MA_2; Predicted membrane protein (DUF2335) Unknown Mitochondrion Chloroplast Complete Q88AB8_PSESM HopAS1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 279 Histidine kinase(HisKA_3) Unknown Chloroplast Nucleus Complete HOAE1_PSEU2 hopAE1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 914 Type III T3SS secreted effector HopW1-1/HopPmaA Unknown Chloroplast Nucleus Complete Q7PC42_PSEU2 HolPtoACPsy Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 2042 PMT_C:C-terminal region of Pasteurella multocida toxin Unknown Chloroplast Chloroplast Complete Q48B68_PSE14 AvrD1 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 311 Pseudomonas avirulence D protein (AvrD) Unknown Any other location Chloroplast Complete Q9L6W4_PSEUB Uncharacterized protein Unknown Tomatoes Pseudomonas syringae pv. tomato Experimentally validated effector 466 PMT_C(C-terminal region of Pasteurella multocida toxin) Unknown Any other location Nucleus Complete AVRP2_PSESJ AvrPpiC2 Potential cysteine protease. Avirulence protein, which may be essential during infection of Plants cells from Pea and some Arabidopsis thaliana cultivars. May act by affecting the Plants defense system. In Plantss lacking appropriate resistance (R) gene, it probably impairs the Plants defense system and leads to the bacteria multiplication. In contrast, in Plantss containing the appropriate R protein, it is unable to induce disease symptoms, explaining its avirulence name Pisi Pseudomonas syringae pv. pisi Experimentally validated effector 269 Peptidase_C58(Yersinia/Haemophilus virulence surface antigen) Unknown Any other location Chloroplast,Nucleus Complete Q88BQ2_PSESM HopX1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 384 None Unknown Any other location Chloroplast,Nucleus Complete HPAB1_PSE14 hopAB1 Effector protein that plays different roles depending on the species and Plants cultivars that interact with the pathogen. Acts as a virulence determinant by enhancing the development of disease symptoms and bacterial growth. Acts as an avirulence factor by eliciting hypersensitive response (HR) and Plants resistance Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 539 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete Q888W0_PSESM HopAI1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 261 VRP3:Salmonella virulence-associated 28kDa protein Unknown Chloroplast Nucleus Complete Q888W3_PSESM HopAG1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 152 None Unknown Chloroplast Chloroplast Complete AVRA_PSESG avrA Unknown Plants Pseudomonas syringae pv. glycinea Experimentally validated effector 907 None Unknown Any other location Chloroplast,Nucleus Complete Q52432_PSESX avrRps4 Unknown Plants Pseudomonas syringae Experimentally validated effector 220 DUF1090 Unknown Chloroplast Nucleus Fragment HOPD1_PSESM hopD1 Effector protein involved in non-host recognition Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 705 None Unknown Chloroplast Nucleus Complete Q887C9_PSESM AvrE1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 1795 AvrE:Pathogenicity factor Unknown Chloroplast Nucleus Complete Q9JP32_PSEUB Uncharacterized protein Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 350 Peptidase_C58(Yersinia/Haemophilus virulence surface antigen) Unknown Any other location Nucleus Complete HOPAD_PSESM hopAD1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 632 Pyr_redox_3(Pyridine nucleotide-disulphide oxidoreductas) Unknown Chloroplast Nucleus Complete Q9L6W3_PSEUB HrpK Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 780 None Unknown Any other location Nucleus Complete D4SZP4_9XANT xopE1 Unknown Plants Xanthomonas fuscans subsp. aurantifolii str. ICPB 11122 Experimentally validated effector 400 None Unknown Chloroplast Chloroplast Complete Q5QA86_XANEU XopP Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 658 None Unknown Chloroplast Chloroplast Complete Q6TQF0_XANEU xopC unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 834 Phosphoribosyl transferase domain; HAD_2:Haloacid dehalogenase-like hydrolase nucleus Any other location Chloroplast,Nucleus Complete Q5RJF5_XANEU XopF1 Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 670 None Unknown Chloroplast Chloroplast,Nucleus Complete Q5QA89_XANEU XopF2 Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 667 None Unknown Chloroplast Nucleus Complete Q5QA92_XANEU XopN Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 733 NAD_binding_3(Homoserine dehydrogenase, NAD binding domain) Unknown Chloroplast Nucleus Complete D4T148_9XANT xopB Unknown Plants Xanthomonas fuscans subsp. aurantifolii str. ICPB 10535 Experimentally validated effector 612 None Unknown Any other location Nucleus Complete Q8RJQ0_XANEU xopD cysteine-type peptidase activity Plants Xanthomonas euvesicatoria Experimentally validated effector 545 Peptidase_C48(Ulp1 protease family, C-terminal catalytic domain) Unknown Any other location Nucleus Complete Q6IV70_XANEU xopX Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 699 Mnd1; Baculo_PEP_C(Baculovirus polyhedron envelope protein, PEP, C terminus) Unknown Any other location Nucleus Complete Q5EN61_XANEU ecf Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 688 None Unknown Any other location Nucleus Complete Q3C000_XANC5 AvrBs1 Unknown Plants Xanthomonas campestris pv. vesicatoria (strain 85-10) Experimentally validated effector 445 None Unknown Any other location Nucleus Complete Q07061_9XANT avrBs4 Unknown Plants Xanthomonas vesicatoria Experimentally validated effector 1160 Xanthomonas avirulence protein, Avr/PthA Unknown Any other location Cell,membrane,Chloroplast,Nucleus Complete Q9Z3F4_XANEU AvrBs2 glycerophosphodiester phosphodiesterase activity Plants Xanthomonas euvesicatoria Experimentally validated effector 714 Glycerophosphoryl diester phosphodiesterase family Unknown Chloroplast Cell,membrane,Chloroplast Complete AVRV_XANEU AvrRxv Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 373 YopJ Serine/Threonine acetyltransferase Unknown Any other location Chloroplast,Nucleus Complete Q9FCY7_ERWST WtsE WtsE is a major virulence factor involved in the elicitation of water-soaked lesions Plants Erwinia stewartii Experimentally validated effector 1835 AvrE(Pathogenicity factor) Unknown Any other location Nucleus Complete A2I8A2_PANAY HsvB Unknown Plants Pantoea agglomerans pv. gypsophilae (Erwinia herbicola) Experimentally validated effector 584 None Unknown Any other location Nucleus Complete NOLB_RHIFR NolB Unknown Soybean Rhizobium fredii (Sinorhizobium fredii) Experimentally validated effector 164 None Unknown Chloroplast Nucleus Complete C4PL72_BRAEL NopA Unknown Soybean Bradyrhizobium elkanii Experimentally validated effector 77 None Unknown Chloroplast Nucleus Complete C4PL71_BRAEL NopC Unknown Soybean Bradyrhizobium elkanii Experimentally validated effector 95 None Unknown Any other location Nucleus Complete NOPL_RHISN NopL Putative symbiotic effector that modulates nodulation in legumes. When delivered into the Plants cell, modulates the activity of signal transduction pathways that culminate in activation of PR proteins Soybean Rhizobium sp. (strain NGR234) Experimentally validated effector 338 None cytoplasm Any other location Nucleus Complete Q50EL2_RHIFR NopP Unknown Soybean Rhizobium fredii (Sinorhizobium fredii) Experimentally validated effector 270 PEP-utilizers_C(PEP-utilising enzyme, TIM barrel domain) Unknown Any other location Nucleus Complete NOPX_RHISN NopX Unknown Soybean Rhizobium sp. (strain NGR234) Experimentally validated effector 596 NolX protein cytoplasm Chloroplast Nucleus Complete Q89TW7_BRADU Blr1656 cellulase activity Soybean Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 268 Glyco_hydro_12 Unknown Any other location Cell,wall Complete Q89TL5_BRADU Blr1904 Unknown Soybean Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 585 Leucine Rich Repeat; C-terminal novel E3 ligase, LRR-interacting Unknown Any other location Cell,wall,Nucleus Complete Y2058_BRADU Blr2058 Potential cysteine protease, which may play a central role after invasion of host cell. Soybean Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 298 Peptidase_C58 Unknown Any other location Nucleus Complete Q89BB8_BRADU Bll8244 Unknown Soybean Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 1441 Peptidase_C48(Ulp1 protease family, C-terminal catalytic domain) Unknown Chloroplast Nucleus Complete Q989M4_RHILO Mlr6361 Unknown Plants Rhizobium loti (strain MAFF303099) (Mesorhizobium loti) Experimentally validated effector 3056 Shikimate kinase Unknown Chloroplast Chloroplast Complete AVRP3_PSESH AvrPphB Cysteine protease avirulence protein, which is essential during infection of Plants cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the Plants defense system. In Plantss lacking R3 or RPS5 resistance genes, it probably impairs the Plants defense system and leads to the bacteria multiplication. In contrast, in Plantss containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the Plants, but are partially dispensable for effector recognition following in Plantsa expression. In infected Plantss, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively. Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 267 Peptidase_C58(Yersinia/Haemophilus virulence surface antigen) membrane Chloroplast Nucleus Complete Q700W1_RALSL PopP1 Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 368 YopJ Unknown Chloroplast Chloroplast,Nucleus Complete C0SPP9_RALSL PopP2 Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 393 YopJ Unknown Chloroplast Chloroplast Complete HPAB3_PSEUB HopAB3 Effector protein involved in gene-for-gene resistance in tomato Plantss. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible Plantss, acts as a virulence factor by suppressing PCD and HR-based Plants immunity. This function requires its E3 ubiquitin ligase activity probably by recruiting E2 enzymes and transferring ubiquitin molecules to cellular proteins involved in regulation of PCD and targeting them for degradation. Enhances the development of disease symptoms and bacterial growth. Plants Pseudomonas syringae pv. tomato Experimentally validated effector 579 AvrPtoB-E3_ubiq cytoplasm Chloroplast Nucleus Complete Q7NUX3_CHRVO SseE Unknown Human Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) Experimentally validated effector 142 Type III secretion system regulator (LcrR) Unknown Any other location Cytoplasm Complete HOPW1_PSEYM hopW1-1 Induces hypersensitive response (HR) Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 774 HopW1-1 Unknown Chloroplast Chloroplast Complete HOPM1_PSEU2 Effector protein hopM1 Involved in the suppression of basal resistance and promotion of disease symptoms in Plantss. May be involved in the inhibition of a host vesicle trafficking pathway. Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 718 None membrane Chloroplast Nucleus Complete HPAB2_PSESM Effector protein HopAB2 Effector protein involved in gene-for-gene resistance in tomato Plantss. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible Plantss, acts as a virulence factor by suppressing PCD and HR-based Plants immunity. This function requires its E3 ubiquitin ligase activity probably by recruiting E2 enzymes and transferring ubiquitin molecules to cellular proteins involved in regulation of PCD and targeting them for degradation. Also, induces expression of host genes involved in ethylene biosynthesis and signaling, in particular ACO1 and ACO2, encoding the ethylene-forming enzyme ACC oxidase. Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 553 AvrPtoB-E3_ubiq cytoplasm Chloroplast Nucleus Complete Q156B7_9XANT PopC Unknown Rice Xanthomonas oryzae pv. oryzicola Experimentally validated effector 656 LRR_4 Unknown Any other location Nucleus Complete HOPD2_PSESM Effector protein hopD2 Effector showing tyrosine-phosphatase activity required for host defense suppression. Functions inside Plants cells causing suppression of HR (hypersensitive response), PR1 gene expression and oxidative burst probably by interfering with a MAPK (mitogen-activated protein kinase) pathway. MAPK cascades are known to activate defense-related transcription factors. Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 468 The N-terminal domain (residues 1-142) retains 70% identity to the N-terminal 142 residues of AvrPphD, and is required for translocation into Plants cells via TTSS. Unknown Chloroplast Chloroplast,Nucleus Complete ARPT2_PSEUB Cysteine protease avirulence protein AvrRpt2 Effector protein involved in gene-for-gene resistance in Plantss expressing RPS2. Its thiol protease activity is required for the degradation of Plants cell RIN4 and consequent activation of RPS2 during bacterial infection. The activation of RPS2 is sufficient for the induction of hypersensitive response (HR) and Plants resistance. Cleavage of RIN4 by AvrRpt2 also interferes with RPM1-mediated resistance activated by either AvrRpm1 or AvrB. Contributes to virulence in Plantss lacking the resistance protein RPS2 promoting pathogen growth and disease symptoms. Inhibits PAMP (pathogen-associated molecular patterns)-induced signaling compromising the hosts basal defense system. Blocks Plants callose deposition, flg22 (a peptide corresponding to the most conserved domain of flagellin) induced accumulation of PR-1, PR-2 and PR-5 and activation of GST6 transcription. The mechanism of virulence is unknown, but this activity is independent of ethylene and salicylic acid response pathways and independent of RIN4 disappearance. Plants Pseudomonas syringae pv. tomato Experimentally validated effector 255 Peptidase_C70 Membrane Chloroplast Chloroplast,Nucleus Complete C0SPQ3_RALSL Type III effector protein Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 451 None Unknown Any other location Peroxisome Complete HPAB1_PSEU2 Effector protein hopAB1 Effector protein that plays different roles depending on the species and Plants cultivars that interact with the pathogen. Acts as a virulence determinant by enhancing the development of disease symptoms and bacterial growth. Acts as an avirulence factor by eliciting hypersensitive response (HR) and Plants resistance. Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 516 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete C8BNV1_PSESY AvrE1 Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 1754 AvrE Unknown Any other location Nucleus Complete Q83XF9_9XANT HpaG Unknown Soybeans Xanthomonas axonopodis pv. glycines Experimentally validated effector 133 Hairpins Unknown Any other location Cell,membrane,Nucleus Complete C0SPQ1_RALSL Type III effector protein Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 425 None Unknown Chloroplast Chloroplast Complete Q7NYG6_CHRVO Hydrophilic protein, virA protein Unknown Human Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) Experimentally validated effector 241 VRP3(Salmonella virulence-associated 28kDa protein) Unknown Any other location Cytoplasm Complete Q6RK53_ERWCR DspE Unknown Plants Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Experimentally validated effector 1614 AvrE Unknown Chloroplast Nucleus Complete C0SPP7_RALSL Type III effector protein GN=avrA Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 267 None Unknown Chloroplast Nucleus Complete Q83YM3_PSESY HopA1 Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 375 None Unknown Any other location Chloroplast Complete C8BNX0_PSESY ExoU Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 629 Patatin Unknown Any other location Vacuole Complete C8BNW8_PSESY HopM1 Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 700 None Unknown Any other location Nucleus Complete Q840G7_PSESY AvrE Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 522 AvrE(Pathogenicity factor) Unknown Chloroplast Nucleus Fragment HPAB3_PSEYM Effector protein hopAB3 Effector protein involved in gene-for-gene resistance in tomato Plantss. It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity. In susceptible Plantss, promotes virulence, in part, by enhancing the development of disease symptoms and bacterial growth. Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 385 None cytoplasm Chloroplast Nucleus Complete AVRD1_PSESH Effector protein AvrPphD Effector protein involved in non-host recognition and able to elicit hypersensitive response (HR). Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 710 None Unknown Chloroplast Nucleus Complete HOAE1_PSE14 Effector protein hopAE1 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 912 HopW1-1 Unknown Chloroplast Nucleus Complete B1GVN9_CITRO EspM3 protein Unknown Rodents Citrobacter Rodentsium Experimentally validated effector 192 IpaB_EvcA Unknown Any other location Cytoplasm, Complete O84626_CHLTR GN=CT_621 Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 832 Effector_1 Unknown Any other location Nucleus Complete B7UMR0_ECO27 Uncharacterized protein Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 191 Pribosyltran Unknown Any other location Membrane Complete B7UI21_ECO27 T3SS secreted effector NleB homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 329 None Unknown Mitochondrion Cytoplasm Complete B7UI22_ECO27 T3SS secreted effector NleE homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 224 None Unknown Any other location Cytoplasm Complete B7UH72_ECO27 T3SS secreted effector EspG homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 390 EspG Unknown Any other location Membrane Complete B7ULW4_ECO27 T3SS secreted effector NleH homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 293 YrbL-PhoP_reg Unknown Any other location Membrane Complete B7UM88_ECO27 LEE-encoded effector EspF Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 206 EspF Unknown Mitochondrion Nucleus Complete TIR_ECO27 Secreted effector protein Tir Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion. In strain E2348/69, acts mainly via the host adaptor proteins NCK1 and NCK2. Once clustered and phosphorylated at Tyr-474, Tir binds to NCK proteins, which in turn bind and activate host WASL/N-WASP, leading to actin polymerization. Can also trigger an inefficient, NCK-independent pedestal formation. This pathway involves phosphorylation of Tyr-454 and probably a putative host adaptor. Acts also via direct binding to the host cytoskeletal protein alpha-actinin in a NCK- and phosphotyrosine-independent manner. This interaction may stabilize the pedestal, but is not essential for its formation. Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 550 The intracellular N-terminal region interacts with host alpha-actinin and is not required for pedestal formation. The central extracellular region (amino acids 277-332) is involved in bacterial intimin binding. The intracellular C-terminal region binds to host NCK. Host cell membrane; Multi-pass membrane protein. Any other location Nucleus Complete B7UMA0_ECO27 LEE-encoded effector Map Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 203 IpaB_EvcA Unknown Mitochondrion Cytoplasm Complete B7UMA2_ECO27 LEE-encoded effector EspH Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 168 Stap_Strp_toxin Unknown Mitochondrion Membrane Complete B7UMC8_ECO27 LEE-encoded effector EspG Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 398 EspG Unknown Any other location Membrane Complete B7UI20_ECO27 T3SS secreted effector EspL homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 549 Toxin_15 Unknown Any other location Cytoplasm Complete B7UNX2_ECO27 T3SS secreted effector NleI/NleG homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 192 DUF1076 Unknown Mitochondrion Endosome Complete B7UNX3_ECO27 T3SS effector-like protein NleB homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 326 None Unknown Any other location Cytoplasm Complete B7UNX4_ECO27 T3SS secreted effector NleC homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 330 Peptidase_M85 Unknown Any other location Membrane Complete B7UNX6_ECO27 T3SS secreted effector NleD homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 232 Peptidase_M91 Unknown Any other location Membrane Complete B7UR63_ECO27 T3SS secreted effector NleF homolog Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 189 None Unknown Any other location Cytoplasm Complete EAEB_ECO27 Protein EaeB Unknown Animals and Humans Escherichia coli O127:H6 (strain E2348/69 / EPEC) Experimentally validated effector 321 EspB Unknown Any other location Cytoplasm Complete A6M3N5_YERPE Translocated host-GTPase-activating protein Unknown Humans and Animals Yersinia pestis CA88-4125 Experimentally validated effector 219 YopE_N; YopE Unknown Any other location Cytoplasm Complete Q7BRY7_YEREN Yop effector YopE Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 219 YopE_N; YopE Unknown Secretory pathway Nucleus Complete A9R9K8_YERPG Protein-tyrosine-phosphatase YopH Unknown Humans and Animals Yersinia pestis bv. Antiqua (strain Angola) Experimentally validated effector 468 YopH_N; Y_phosphatase Unknown Any other location Membrane Complete Q7BRY8_YEREN Yop effector YopH Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 468 YopH_N; Y_phosphatase Unknown Any other location Membrane Complete B0A3S4_YERPE YopK protein Unknown Humans and Animals Yersinia pestis biovar Orientalis str. F1991016 Experimentally validated effector 182 None Unknown Any other location Cytoplasm Complete Q56935_YERPU YopK Unknown Humans and Animals Yersinia pseudotuberculosis Experimentally validated effector 182 None Unknown Any other location Cytoplasm Complete Q7BS06_YEREN YopQ Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 182 None Unknown Any other location Cytoplasm Complete B0HNN9_YERPE Effector protein YopJ Unknown Humans and Animals Yersinia pestis biovar Antiqua str. B42003004 Experimentally validated effector 288 YopJ Unknown Any other location Membrane Complete Q93KQ5_YEREN Yop effector YopP Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 288 YopJ Unknown Any other location Cytoplasm Complete B0A3S3_YERPE Cysteine protease YopT Unknown Humans and Animals Yersinia pestis biovar Orientalis str. F1991016 Experimentally validated effector 322 Peptidase_C58 Unknown Any other location Secreted Complete YOPT_YERPS Cysteine protease YopT Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the Humans small GTPase RhoA/ARHA, a regulator of cytoskeleton. Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell. Humans and Animals Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 322 Peptidase_C58 Cytoplasm Any other location Secreted Complete YOPT1_YEREN Cysteine protease yopT1 Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the Humans small GTPase RhoA/ARHA, a regulator of cytoskeleton. Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell. Humans and Animals Yersinia enterocolitica Experimentally validated effector 322 Peptidase_C58 Cytoplasm Any other location Secreted Complete A9ZFE7_YERPE Protein kinase YopO Unknown Humans and Animals Yersinia pestis biovar Orientalis str. IP275 Experimentally validated effector 732 Pkinase Rac1 Unknown Any other location Nucleus Complete YPKA_YERPS Protein kinase YpkA Acts as a virulence determinant. Humans and Animals Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 732 Pkinase Rac1 Unknown Any other location Nucleus Complete Q56921_YEREN Protein kinase A Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 728 Pkinase Rac1 Unknown Any other location Cytoplasm Complete O85239_YEREN Protein kinase YopO Unknown Humans and Animals Yersinia enterocolitica Experimentally validated effector 729 Pkinase Rac1 Unknown Any other location Mitochondrion Complete A9ZER0_YERPE Type III secretion protein YopR Unknown Humans and Animals Yersinia pestis biovar Orientalis str. IP275 Experimentally validated effector 165 YopR_core Unknown Mitochondrion Cytoplasm Complete YSCH_YERPS Yop proteins translocation protein H Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. Humans and Animals Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 165 YopR_core Unknown Mitochondrion Nucleus Complete O34020_CHLCI CopN protein Unknown Guinea pigs Chlamydophila caviae Experimentally validated effector 397 HrpJ Unknown Any other location Cytoplasm Complete Q58I88_ECOLX Translocated intimin receptor Unknown Animals and Humans Escherichia coli Experimentally validated effector 574 Tir_receptor_N; Tir_receptor_M; Tir_receptor_C Unknown Any other location Nucleus Complete Q47184_ECOLX EspA Unknown Animals and Humans Escherichia coli Experimentally validated effector 192 EspA Unknown Any other location Nucleus Complete O85646_ECOLX EspG Unknown Animals and Humans Escherichia coli Experimentally validated effector 398 EspG Unknown Any other location Membrane Complete ESFU2_ECO57 Secreted effector protein EspF(U) Required for efficient pedestal formation in host epithelial cells during infection. Acts as an intermediate between Tir (via host BAIAP2) and host WASL/N-WASP. Directly binds and activates WASL/N-WASP, which stimulates actin polymerization and leads to the formation of actin pedestals at the sites of bacterial adhesion. Animals and Humans Escherichia coli O157:H7 Experimentally validated effector 337 The N-terminal 21 amino acids are necessary and sufficient for translocation into the host cell. The C-terminal region, composed of several highly conserved proline-rich repeats, interacts with the SH3 domain of BAIAP2 and BAIAP2L1, and the GTPase binding domain (GBD) of WASL/N-WASP and WAS/WASP. The N-terminal translocation signal and two proline-rich repeats are sufficient for triggering actin polymerization, but each additional repeat gives higher activity Cytoplasm Mitochondrion Nucleus Complete B2NN32_ECO57 NleB Unknown Animals and Humans Escherichia coli O157:H7 str. EC4196 Experimentally validated effector 329 None Unknown Mitochondrion Cytoplasm Complete Q8XBX7_ECOLX ST47 protein Unknown Animals and Humans Escherichia coli Experimentally validated effector 224 Phage_FRD3 Unknown Any other location Cytoplasm Complete YOPE_YERPS Outer membrane virulence protein YopE Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis. Animals and Humans Yersinia pseudotuberculosis serotype I (strain IP32953) Experimentally validated effector 219 YopE_N; YopE Cell outer membrane Any other location Cytoplasm Complete YOPE_YEREN Outer membrane virulence protein YopE Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis. Animals and Humans Yersinia enterocolitica Experimentally validated effector 219 YopE_N; YopE Cell outer membrane Secretory pathway Nucleus Complete YOPH_YEREN Tyrosine-protein phosphatase YopH Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages. Animals and Humans Yersinia enterocolitica Experimentally validated effector 468 YopH_N; Y_phosphatase Unknown Any other location Membrane Complete YPKA_YERPE Protein kinase YpkA Acts as a virulence determinant. Animals and Humans Yersinia pestis Experimentally validated effector 732 Pkinase Rac1 Unknown Any other location Nucleus Complete YSCH_YERPE Yop proteins translocation protein H Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. Animals and Humans Yersinia pestis Experimentally validated effector 165 YopR_core Unknown Mitochondrion Cytoplasm Complete B5MXT4_SALET Secreted effector protein Unknown Animals and Humans Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. CVM23701 Experimentally validated effector 782 Pentapeptide_4; SopA; SopA_C Unknown Any other location Nucleus Complete B2PHR1_ECO57 EspF Unknown Animals and Humans Escherichia coli O157:H7 str. EC4076 Experimentally validated effector 248 EspF Unknown Mitochondrion Nucleus Complete B3A307_ECO57 NleB Unknown Animals and Humans Escherichia coli O157:H7 str. EC4401 Experimentally validated effector 329 None Unknown Mitochondrion Cytoplasm Complete B3BS59_ECO57 NleE Unknown Animals and Humans Escherichia coli O157:H7 str. EC508 Experimentally validated effector 224 Phage_FRD3 Unknown Any other location Cytoplasm Complete TARP_CHLTR Translocated actin-recruiting phosphoprotein Appears to initiate or participate in signaling events that regulate the actin recruitment, which ultimately leads to internalization. Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 1005 DUF1547 Unknown Any other location Nucleus Complete Y572_CHLPN Uncharacterized protein CPn_0572/CP_0177/CPj0572/CpB0594 Unknown Humans Chlamydia pneumoniae (Chlamydophila pneumoniae) Experimentally validated effector 755 DUF1547 Unknown Any other location Membrane Complete Q9Z8Z8_CHLPN CPj0186 protein Unknown Humans Chlamydia pneumoniae (Chlamydophila pneumoniae) Experimentally validated effector 390 IncA Unknown Any other location Cytoplasm Complete INCD_CHLT2 Inclusion membrane protein D Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion. Humans Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) Experimentally validated effector 146 DUF1700 Host cell membrane Any other location Membrane Complete INCE_CHLT2 Inclusion membrane protein E Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion. Humans Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) Experimentally validated effector 132 DUF417; 7TMR-DISM_7TM Host cell membrane Any other location Membrane Complete INCF_CHLT2 Inclusion membrane protein F Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion. Humans Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) Experimentally validated effector 104 None Host cell membrane Any other location Membrane Complete Q3KMQ1_CHLTA Inclusion membrane protein G Unknown Humans Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) Experimentally validated effector 167 Amastin; RecT; O-antigen_lig Unknown Secretory pathway Membrane Complete SPAN_SALTY Invasion protein InvJ Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 336 SPAN(Surface presentation of antigens protein) Unknown Any other location Cytoplasm Complete SIFA_SALTY Secreted effector protein SifA Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required for endosomal tubulation and formation of Salmonella-induced filaments (Sifs), which are filamentous structures containing lysosomal membrane glycoproteins within epithelial cells. Sif formation is concomitant with intracellular bacterial replication. Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 336 Domains throughout the protein, and not only the N-terminus, are required for secretion and translocation. Both N- and C-terminal domains are also required for formation of tubules. Cytoplasm; Cell membrane Any other location Cytoplasm Complete Q57QR2_SALCH Outer protein Unknown Humans Salmonella choleraesuis (strain SC-B67) Experimentally validated effector 561 IpgD Unknown Any other location Cytoplasm Complete Q8ZMI3_SALTY avrA Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 302 YopJ Unknown Any other location Nucleus Complete SIPD_SALTY Cell invasion protein SipD Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC. Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 343 The N-terminal domain is an intra-molecular chaperone that prevents premature oligomerization of the residues on the coiled-coil region that are involved in interactions with the needle and/or itself. The residues in the C-terminal domain probably form oligomeric structures at the tip of the needle that are responsible for the regulation of secretion of other effectors IpaD Any other location Nucleus Complete SPVC_SALTY MAPK phosphothreonine lyase gene name=spvC Secreted effector that irreversibly inactivates host MAP kinases by catalyzing the dephosphorylation of the phosphothreonine residue in the pT-X-pY motif in MAPK2/ERK2, MAPK3/ERK1, and p38, via a beta-elimination reaction leading to a dehydrobutyrine residue. Is also able to remove the phosphate group from phospho-JNK in vitro, but JNK may not be a substrate in vivo. Could help suppress localized proinflammatory responses at infection foci in the spleen and liver, and thereby facilitate bacterial growth. Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 241 VRP3 Cytoplasm Any other location Cytoplasm Complete H9L477_SALTY Salmonella plasmid virulence: hydrophilic protein gene name=spvB Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 591 SpvB ADPrib_exo_Tox Unknown Secretory pathway Cytoplasm Complete SOPD2_SALTY Secreted effector protein sopD2 Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to the formation of Salmonella-induced filaments (Sifs) in infected epithelial cells and to replication in macrophages. Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 319 The N-terminal domain mediates secretion by SPI-2 TTSS and targeting of late endocytic compartments in host cells. Host cell membrane Mitochondrion Nucleus Complete SPIC_SALTY Secretion system apparatus protein B Virulence protein that plays a central role in mammalian macrophage infection, by inhibiting phagosome-lysosome fusion and cellular trafficking. May act by disrupting the function of the mammalian HOOK3 protein, a protein involved in the cellular traffic. Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 133 None Cytoplasm Any other location Membrane Complete H9L407_SALTY Secretion system effector sseF Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 260 None Unknown Any other location Membrane Complete H9L486_SALTY Secretion system effector sseG Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 229 None Unknown Any other location Membrane Complete Q8ZNP4_SALTY Putative cytoplasmic protein Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 348 None Unknown Mitochondrion Secreted Complete Q2QHF9_SALTM Putative cytoplasmic protein Unknown Humans Salmonella typhimurium Experimentally validated effector 14 None Unknown Any other location None Fragment Q8ZN18_SALTY Gifsy-1 prophage leucine-rich repeat protein Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 497 FNIP Unknown Any other location Nucleus Complete Q9L9J3_SALTY Putative cytoplasmic protein Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 336 None Unknown Any other location Cytoplasm Complete Q8ZQA1_SALTY Gifsy-2 prophage protein Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 170 PipA Unknown Any other location Nucleus Complete Q8ZMY7_SALTY Gifsy-1 prophage protein Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 228 PipA Unknown Any other location Membrane Complete H9L446_SALTY Secretion system effector sseE Unknown Humans Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Experimentally validated effector 138 LcrR Unknown Any other location Endoplasmic Complete O84949_SALTM SseE Unknown Humans Salmonella typhimurium Experimentally validated effector 138 LcrR Unknown Any other location Endoplasmic Complete Y875_CHLTR Uncharacterized protein CT_875 Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 591 None Unknown Any other location Nucleus Complete O84056_CHLTR Putative uncharacterized protein Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 148 IncA; Spc7 Unknown Any other location Nucleus Complete O84107_CHLTR Putative uncharacterized protein Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 656 None Unknown Any other location Membrane Complete O84144_CHLTR Putative uncharacterized protein Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 285 None Unknown Any other location Membrane Complete K0GGG6_CHLTH Uncharacterized protein Unknown Humans Chlamydia trachomatis Experimentally validated effector 280 Staphylcoagulse Unknown Any other location Membrane Complete O84163_CHLTR Putative uncharacterized protein Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 246 None Unknown Any other location Nucleus Complete O84342_CHLTR Putative uncharacterized protein Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 153 None Unknown Any other location Endoplasmic Complete Y429_CHLTR UPF0158 protein CT_429 Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 329 UPF0158 Unknown Secretory pathway Nucleus Complete O84856_CHLTR Putative uncharacterized protein Unknown Humans Chlamydia trachomatis (strain D/UW-3/Cx) Experimentally validated effector 159 DUF720 Unknown Any other location Nucleus Complete B2SIB7_XANOP XopQ effector Unknown Plants Xanthomonas oryzae pv. oryzae (strain PXO99A) Experimentally validated effector 395 IU_nuc_hydro Unknown Any other location Chloroplast Complete Q89N83_BRADU Nodulation protein N Unknown Soybeans Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 159 MaoC_dehydratas Unknown Any other location Chloroplast Complete Q89TP9_BRADU Nodulation protein Unknown Soybeans Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 170 None Unknown Chloroplast Nucleus Complete Q79UN8_BRADU Bll1862 protein Unknown Soybeans Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) Experimentally validated effector 180 None Unknown Any other location Cytoplasm Complete Q989P6_RHILO Mlr8763 protein Unknown Plants Rhizobium loti (strain MAFF303099) (Mesorhizobium loti) Experimentally validated effector 167 MxiH Unknown Any other location Nucleus Complete Q989P8_RHILO Nodulation protein NolX Unknown Plants Rhizobium loti (strain MAFF303099) Experimentally validated effector 634 NolX Unknown Any other location Nucleus Complete NOLB_RHISN Nodulation protein NolB Unknown Plants Rhizobium sp. (strain NGR234) Experimentally validated effector 164 None Unknown Chloroplast Nucleus Complete Q5Y4S2_RHIFR Nodulation protein Unknown Plants Rhizobium fredii (Sinorhizobium fredii) Experimentally validated effector 596 NolX Unknown Chloroplast Nucleus Complete Q7BMF3_RHIFR Type III effector NopB Unknown Plants Rhizobium fredii (Sinorhizobium fredii) Experimentally validated effector 164 None Unknown Chloroplast Nucleus Complete Q52537_PSESX AvrPmaA1 protein Unknown Plants Pseudomonas syringae Experimentally validated effector 220 PARP(Poly(ADP-ribose) polymerase catalytic domain) Unknown Any other location Nucleus Complete Q52530_PSESH avrD Unknown Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 311 AvrD Unknown Any other location Chloroplast Fragment Q52394_PSESH AvrPphE protein Unknown Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 380 SBP_bac_5 Unknown Chloroplast Nucleus Complete Q7PC45_PSEU2 Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 716 NUDIX Unknown Chloroplast Chloroplast Complete Q87XS5_PSESM Type III helper protein HopAK1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 555 Pec_lyase_C Unknown Any other location Nucleus Complete G7TIR4_9XANT Type III effector protein XopQ Unknown rice Xanthomonas oryzae pv. oryzicola BLS256 Experimentally validated effector 464 IU_nuc_hydro Unknown Chloroplast Chloroplast,Nucleus Complete G2M1B8_9XANT Putative uncharacterized protein xopQ Unknown Plants Xanthomonas axonopodis pv. citrumelo F1 Experimentally validated effector 464 IU_nuc_hydro Unknown Any other location Chloroplast Complete U4M422_9XANT type III effector XopQ Unknown Plants Xanthomonas fuscans subsp. fuscans Experimentally validated effector 464 IU_nuc_hydro Unknown Chloroplast Chloroplast Complete Q5QA88_XANEU XopQ Unknown Plants Xanthomonas euvesicatoria Experimentally validated effector 464 IU_nuc_hydro Unknown Any other location Chloroplast Complete H2BNV7_XANCJ Type III effector protein xopQ Unknown Plants Xanthomonas campestris pv. juglandis (Xanthomonas arboricola pv. juglandis) Experimentally validated effector 282 IU_nuc_hydro Unknown Any other location Chloroplast Fragment H2BNU5_9XANT Type III effector protein xopQ Unknown Plants Xanthomonas arboricola pv. pruni Experimentally validated effector 282 IU_nuc_hydro Unknown Any other location Chloroplast Fragment H2BNU9_9XANT Type III effector protein xopQ Unknown Plants Xanthomonas arboricola pv. corylina Experimentally validated effector 282 IU_nuc_hydro Unknown Any other location Chloroplast Fragment H2EMV1_9XANT T3SS effector protein Unknown Plants Xanthomonas axonopodis pv. punicae Experimentally validated effector 291 IU_nuc_hydro Unknown Chloroplast Chloroplast Fragment D4T570_9XANT Type III secretion system effector protein Unknown Plants Xanthomonas fuscans subsp. aurantifolii str. ICPB 10535 Experimentally validated effector 464 IU_nuc_hydro Unknown Chloroplast Chloroplast Complete D4SSF7_9XANT Type III secretion system effector protein Unknown Plants Xanthomonas fuscans subsp. aurantifolii str. ICPB 11122 Experimentally validated effector 464 IU_nuc_hydro Unknown Chloroplast Chloroplast Complete R4TJS0_XANOO Type III effector protein Unknown Plants Xanthomonas oryzae pv. oryzae Experimentally validated effector 395 IU_nuc_hydro Unknown Any other location Chloroplast Fragment E7PKT3_PSESG Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. glycinea str. race 4 Experimentally validated effector 1714 AvrE Unknown Chloroplast Cytoplasm,Nucleus Complete J7IHF5_PSESF Type III effector avirulence E1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 161 AvrE Unknown Chloroplast Nucleus Fragment J7I9R7_PSESF Avirulence E1 effector Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 165 AvrE Unknown Chloroplast Nucleus Fragment J7I9W8_PSESF Avirulence E1 effector Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 164 AvrE Unknown Chloroplast Nucleus Fragment J7IA88_PSESF Type III effector avirulence E1 Unknown Plants Pseudomonas syringae pv. actinidiae str. NCPPB 3871 Experimentally validated effector 165 AvrE Unknown Chloroplast Nucleus Fragment Q8RNY8_PSEYM Type III effector AvrEPma Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 1160 AvrE Unknown Any other location Nucleus Fragment S6W8W7_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete F3IDS2_PSESL Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 1753 AvrE Unknown Chloroplast Nucleus Complete S6P8I4_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete S6WML3_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete S6KIP8_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 1800 AvrE Unknown Chloroplast Nucleus Complete S6MMK8_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 321 AvrE Unknown Chloroplast Nucleus Fragment S6MLH2_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 1476 AvrE Unknown Chloroplast Nucleus Fragment S6TX61_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 1475 AvrE Unknown Chloroplast Nucleus Fragment S6TX97_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 332 AvrE Unknown Chloroplast Nucleus Fragment Q7BM43_PSEUB AvrE Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 1795 AvrE Unknown Chloroplast Nucleus Complete F3FD38_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. japonica str. M301072 Experimentally validated effector 1610 AvrE Unknown Any other location Cytoplasm,Nucleus Complete F3IUT8_PSEAP Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. aptata str. DSM 50252 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm,Nucleus Complete S6R245_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete B5SD96_RALSL Type III effector protein Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 1728 AvrE Unknown Mitochondrion Chloroplast Complete J7IGK1_PSESF Type III effector avirulence E1 Unknown Plants Pseudomonas syringae pv. actinidiae str. NCPPB 3739 Experimentally validated effector 165 AvrE Unknown Chloroplast Nucleus Fragment S6RWT6_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 1800 AvrE Unknown Chloroplast Nucleus Complete S6NB30_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete S6VX70_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 1478 AvrE Unknown Any other location Nucleus Fragment S6VZN9_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 320 AvrE Unknown Chloroplast Nucleus Fragment J7I9E2_PSESF Avirulence E1 effector Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 158 AvrE Unknown Chloroplast Nucleus Fragment J7IDX1_PSESF Type III effector avirulence E1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 159 AvrE Unknown Chloroplast Nucleus Fragment J7I9W3_PSESF Avirulence E1 effector Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 157 AvrE Unknown Chloroplast Nucleus Fragment J7IHF0_PSESF Type III effector avirulence E1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 162 AvrE Unknown Chloroplast Nucleus Fragment S6N442_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete F2ZUJ4_9PSED Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 65 None Unknown Mitochondrion Nucleus Fragment F2ZKF4_9PSED Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 1667 AvrE Unknown Chloroplast Cytoplasm Complete F2ZWN8_9PSED Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 65 None Unknown Mitochondrion Nucleus Fragment F2ZKF1_9PSED Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 1168 AvrE Unknown Any other location Cytoplasm Complete F2ZKF2_9PSED Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 382 AvrE Unknown Any other location Nucleus Fragment S6TBE1_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 1467 AvrE Unknown Chloroplast Nucleus Fragment S6PYE1_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 1471 AvrE Unknown Any other location Nucleus Fragment S6RAM0_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 335 AvrE Unknown Chloroplast Nucleus Fragment S6TBG5_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 333 AvrE Unknown Chloroplast Nucleus Fragment F3GVK0_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm,Nucleus Complete F3HEG5_PSEYM Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 1704 AvrE Unknown Chloroplast Nucleus Complete S6R7D0_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 1758 AvrE Unknown Chloroplast Nucleus Complete F3HVG1_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete S6VNA0_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 1206 AvrE Unknown Chloroplast Nucleus Fragment S6WZB7_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 42 AvrE Unknown Any other location None Fragment L7GZH5_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae BRIP39023 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm,Nucleus Complete S6M7E2_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 329 AvrE Unknown Chloroplast Nucleus Complete S6NL65_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 1480 AvrE Unknown Any other location Nucleus Fragment F3DQ26_9PSED Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 1801 AvrE Unknown Chloroplast Nucleus Complete S3NG30_PSESY Type III secretion system effector AvrE1 Unknown Plants Pseudomonas syringae pv. syringae SM Experimentally validated effector 1789 AvrE Unknown Chloroplast Nucleus Complete S6N7Z7_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete F3JWA0_PSESZ Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 1729 AvrE Unknown Any other location Cytoplasm,Nucleus Complete L7GEC7_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae BRIP34881 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm,Nucleus Complete E2MBX7_PSEUB Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 1767 AvrE Unknown Chloroplast Nucleus Complete S6PEP6_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 321 AvrE Unknown Chloroplast Nucleus Fragment S6WI91_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 1801 AvrE Unknown Any other location Nucleus Complete S6UJA0_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 1800 AvrE Unknown Chloroplast Nucleus Complete S6RRC4_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 331 AvrE Unknown Chloroplast Nucleus Fragment S6RRN4_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 1479 AvrE Unknown Any other location Nucleus Fragment S6TWG5_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 314 AvrE Unknown Chloroplast Chloroplast,Nucleus Fragment S6SWN6_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 1463 AvrE Unknown Chloroplast Nucleus Fragment E7P9D7_PSESG Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. glycinea str. B076 Experimentally validated effector 1714 AvrE Unknown Chloroplast Nucleus Complete K6C9A8_PSEVI Type III effector protein AvrE1 Unknown Plants Pseudomonas viridiflava UASWS0038 Experimentally validated effector 1719 AvrE Unknown Chloroplast Nucleus Complete F3JBG9_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm,Nucleus Complete K2U905_PSESY Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 1789 AvrE Unknown Chloroplast Nucleus Complete K2TJT1_PSESY Type III effector AvrE Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe037 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm Complete F3DNV4_9PSED Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 1714 AvrE Unknown Chloroplast Cytoplasm,Nucleus Complete L7GCB8_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 1620 AvrE Unknown Any other location Cytoplasm,Nucleus Complete S6MUD3_PSESX Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 1749 AvrE Unknown Chloroplast Nucleus Complete S6MGM1_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 334 AvrE Unknown Chloroplast Nucleus Fragment S6L7M0_PSESF Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 1474 AvrE Unknown Any other location Nucleus Fragment F3G242_PSESJ Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 1746 AvrE Unknown Chloroplast Nucleus Complete L8NJX0_PSESY Type III secretion system effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 1789 AvrE Unknown Chloroplast Nucleus Complete F3EA66_PSESL Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 1729 AvrE Unknown Mitochondrion Cytoplasm,Nucleus Complete Q8XQE6_RALSO Putative type III effector protein Unknown Plants Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) Experimentally validated effector 1742 AvrE Unknown Any other location Chloroplast Complete D8N1C5_RALSL Putative type III effector protein, HopR1 family Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 1681 AvrE Unknown Chloroplast Chloroplast Complete Q4ZX80_PSEU2 Type III effector protein AvrE1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 1786 AvrE Unknown Chloroplast Nucleus Complete Q48M45_PSE14 Type III effector AvrE1 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 1714 AvrE Unknown Chloroplast Cytoplasm,Nucleus Complete M7CP80_PSESS Type III effector Unknown Plants Pseudomonas savastanoi pv. savastanoi NCPPB 3335 Experimentally validated effector 1718 AvrE Unknown Chloroplast Cytoplasm,Nucleus Complete S6XHX4_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 134 None Unknown Mitochondrion Nucleus Complete S6P8X2_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete S6WPR6_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 134 None Unknown Mitochondrion Nucleus Complete S6SGG6_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete S6VZE2_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 134 None Unknown Mitochondrion Nucleus Complete S6PYV4_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete F3I656_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete S6M685_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 134 None Unknown Mitochondrion Nucleus Complete S6M2H0_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete S6QJX1_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete S6VEQ3_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 134 None Unknown Mitochondrion Nucleus Complete S6RVC5_PSESF Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete F3JJF1_PSESX Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 104 None Unknown Any other location Nucleus Complete S6MYZ5_PSESX Type III effector protein AvrRpm1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 134 None Unknown Chloroplast Nucleus Complete E7PH30_PSESG Type III effector AvrRps4 Unknown Plants Pseudomonas syringae pv. glycinea str. race 4 Experimentally validated effector 64 None Unknown Any other location Nucleus Complete F3DTU5_9PSED Type III effector AvrRps4 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 160 DUF1090 Unknown Mitochondrion Nucleus Fragment K2T7W2_9PSED Type III effector AvrRps4 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 221 None Unknown Chloroplast Nucleus Complete F3GEX7_PSESJ Type III effector AvrRps4 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 64 None Unknown Any other location Nucleus Complete Q48B92_PSE14 Type III effector AvrRps4 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 221 None Unknown Chloroplast Nucleus Complete J7IHN8_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 134 None Unknown Chloroplast Nucleus Fragment J7I9V5_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 134 None Unknown Any other location Nucleus Fragment S6WUK4_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 139 None Unknown Any other location Chloroplast,Mitochondrion Complete S6Y6D4_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 197 None Unknown Any other location Nucleus Complete F3IJ53_PSESL Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 380 None Unknown Any other location Chloroplast,Nucleus Complete S6W0T5_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 197 None Unknown Any other location Nucleus Complete S6VV43_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 139 None Unknown Any other location Chloroplast,Mitochondrion Complete S6KYY3_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 122 None Unknown Any other location Chloroplast,Mitochondrion,Nucleus Fragment S6MCJ0_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 295 None Unknown Any other location Nucleus Complete S6T207_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 149 None Unknown Any other location Chloroplast,Nucleus Fragment S6T5X3_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 260 None Unknown Any other location Nucleus Complete S6SNR1_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete S6THS0_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete S6M855_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 307 None Unknown Mitochondrion Chloroplast Complete S6UU72_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 197 None Unknown Any other location Nucleus Complete S6VYU1_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 139 None Unknown Any other location Chloroplast,Mitochondrion Complete J7I9B7_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 127 None Unknown Any other location Nucleus Fragment J7IG74_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 117 None Unknown Chloroplast Nucleus Fragment J7IG80_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 131 None Unknown Mitochondrion Nucleus Fragment J7I9V0_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 127 None Unknown Mitochondrion Nucleus Fragment J7IE52_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 125 None Unknown Mitochondrion Nucleus Fragment J7I9B3_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 130 None Unknown Mitochondrion Nucleus Fragment J7IGZ7_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 125 None Unknown Mitochondrion Nucleus Fragment J7IDH5_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae Experimentally validated effector 132 None Unknown Any other location Nucleus Fragment S6PKD8_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 105 None Unknown Any other location Cell,membrane,Chloroplast,Mitochondrion,Nucleus Complete S6PRL9_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 205 None Unknown Mitochondrion Chloroplast,Nucleus Complete S6V1K6_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete F3GVG9_PSESX Type III effector HopA1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 375 None Unknown Any other location Chloroplast Complete S6RRP3_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete S6TJ80_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 295 None Unknown Any other location Nucleus Fragment S6U8L8_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 116 None Unknown Mitochondrion Chloroplast,Mitochondrion,Nucleus Fragment L7H0L5_PSESX Type III effector HopA1 Unknown Plants Pseudomonas syringae BRIP39023 Experimentally validated effector 375 None Unknown Any other location Chloroplast Complete S6NX15_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 197 None Unknown Any other location Nucleus Complete S6PBC9_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 139 None Unknown Any other location Chloroplast,Mitochondrion Complete F3E2I8_9PSED Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 377 None Unknown Any other location Chloroplast,Nucleus Complete F3E2I7_9PSED Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 43 None Unknown Mitochondrion None Complete S6X1Q5_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 139 None Unknown Any other location Chloroplast,Mitochondrion Complete S6WZ37_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 197 None Unknown Any other location Nucleus Complete S6V323_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete S6W322_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete F3DIZ8_9PSED Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 368 None Unknown Any other location Chloroplast Fragment S6MHN1_PSESX Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 380 None Unknown Any other location Nucleus Complete S6NBV7_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 105 None Unknown Any other location Cell,membrane,Chloroplast,Mitochondrion,Nucleus Complete S6LY30_PSESF Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 205 None Unknown Mitochondrion Chloroplast,Nucleus Complete F3G1H5_PSESJ Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 376 None Unknown Any other location Nucleus Complete F3EA95_PSESL Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 375 None Unknown Any other location Chloroplast Complete Q87UE5_PSESM Type III effector HopA1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 380 None Unknown Any other location Nucleus Complete F2ZV36_9PSED Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 87 None Unknown Any other location Cell,membrane,Cytoplasm,Golgi,apparatus,Mitochondrion Fragment S6XJG2_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 90 None Unknown Any other location Nucleus Fragment S6W8W3_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 354 None Unknown Any other location Mitochondrion Fragment S6W2C8_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 90 None Unknown Any other location Nucleus Fragment F3IDS7_PSESL Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 486 None Unknown Mitochondrion Nucleus Complete S6PF37_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete S6XUP2_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 90 None Unknown Any other location Nucleus Fragment S6Y3F5_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 146 None Unknown Chloroplast Nucleus Fragment S6WML8_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 354 None Unknown Any other location Mitochondrion Fragment S6KIP2_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 456 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Cytoplasm,Nucleus Complete S6TXC8_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 456 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Cytoplasm,Nucleus Complete S6NUA6_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 112 None Unknown Secretory pathway Nucleus Fragment S6NUC8_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 57 None Unknown Any other location Nucleus Fragment F3FD33_PSESX Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. japonica str. M301072 Experimentally validated effector 483 None Unknown Chloroplast Chloroplast,Cytoplasm,Nucleus Complete F3IUT4_PSEAP Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. aptata str. DSM 50252 Experimentally validated effector 485 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete S6R237_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete S6RX77_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 456 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Cytoplasm,Nucleus Complete S6NHL4_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete S6X6M9_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 111 None Unknown Any other location Nucleus Fragment S6XE95_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 97 None Unknown Any other location Nucleus Fragment S6XE84_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 237 None Unknown Any other location Mitochondrion Complete S6X1P7_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 354 None Unknown Any other location Mitochondrion Fragment S6VVV6_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 90 None Unknown Any other location Nucleus Fragment S6P496_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete F2ZWE8_9PSED Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 157 None Unknown Mitochondrion Mitochondrion Fragment F2ZKE6_9PSED Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 359 None Unknown Chloroplast Nucleus Fragment F2ZM92_9PSED Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 184 None Unknown Any other location Nucleus Fragment F2ZG47_9PSED Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 126 None Unknown Any other location Nucleus Fragment F2ZXM1_9PSED Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 134 None Unknown Any other location Cytoplasm,Golgi,apparatus,Mitochondrion Fragment F2ZE21_9PSED Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 120 None Unknown Any other location Cell,membrane Fragment F2ZUM0_9PSED Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 113 None Unknown Secretory pathway Cell,membrane Fragment S6PXW1_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete S6UL73_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 456 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Cytoplasm,Nucleus Complete F3GVK6_PSESX Type III effector HopAA1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete F3HEG0_PSEYM Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 484 None Unknown Chloroplast Mitochondrion Complete S6JQB0_9PSED Putative type III effector, HopAA1 family protein Unknown Plants Pseudomonas sp. CFII68 Experimentally validated effector 451 None Unknown Chloroplast Cell,membrane,Cell,wall,Nucleus Complete F3HPT6_PSEYM Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 435 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6R7C5_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 456 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Cytoplasm,Nucleus Complete F3HVG5_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete S6WZB3_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 99 None Unknown Any other location Nucleus Fragment S6WSJ7_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 35 None Unknown Any other location None Fragment L7GZI0_PSESX Type III effector HopAA1 Unknown Plants Pseudomonas syringae BRIP39023 Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete T2QVX5_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 90 None Unknown Any other location Nucleus Fragment S6MEY2_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 354 None Unknown Any other location Mitochondrion Fragment S6MD08_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 142 None Unknown Chloroplast Nucleus Fragment S3NG26_PSESY Type III secretion system effector HopAA1 Unknown Plants Pseudomonas syringae pv. syringae SM Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete S6NEK8_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete L7GEC2_PSESX Type III effector HopAA1 Unknown Plants Pseudomonas syringae BRIP34881 Experimentally validated effector 485 None Unknown Any other location Nucleus Complete E2MBY1_PSEUB Type III effector hopAA1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 486 None Unknown Chloroplast Nucleus Complete S6QRU5_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 201 None Unknown Any other location Nucleus Fragment S6VGN1_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 90 None Unknown Any other location Nucleus Fragment S6VCC4_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 355 None Unknown Any other location Mitochondrion Fragment S6VBC3_PSESF Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 142 None Unknown Chloroplast Nucleus Fragment S6VJP6_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 456 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Cytoplasm,Nucleus Complete S6RWI9_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete S6SWQ6_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 333 None Unknown Any other location Mitochondrion Fragment S6TWP0_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 130 None Unknown Any other location Nucleus Fragment F3JBH4_PSESX Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete K2U8Z8_PSESY Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete K2TJS5_PSESY Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe037 Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete K2T0X1_9PSED Type III effector HopAA1-1 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 485 None Unknown Chloroplast Nucleus Complete L7GCB6_PSESX Type III effector HopAA1 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 485 None Unknown Any other location Nucleus Complete K2SVJ4_9PSED Type III effector HopAA1-2 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 487 None Unknown Chloroplast Cell,membrane,Chloroplast,Cytoplasm,Mitochondrion,Nucleus Complete S6MUD9_PSESX Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 456 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6MNS0_PSESF Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 456 None Unknown Any other location Nucleus Complete F3G248_PSESJ Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 485 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete L8NJX2_PSESY Type III secretion system effector HopAA1 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete F3EA62_PSESL Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 486 None Unknown Chloroplast Cytoplasm,Nucleus Complete Q4ZX85_PSEU2 Type III effector HopAA1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 483 None Unknown Chloroplast Nucleus Complete G3XDB9_PSESM Type III effector HopAA1-1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 486 None Unknown Mitochondrion Nucleus Complete Q87W48_PSESM Type III effector HopAA1-2 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 487 None Unknown Chloroplast Cell,membrane,Chloroplast,Cytoplasm,Mitochondrion,Nucleus Complete F2ZKN4_9PSED Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 219 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete I1V8B0_PSEYM AvrPtoB type III effector Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 511 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Fragment I1V8A9_PSEYM AvrPtoB type III effector Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 485 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Fragment F3IHD9_PSESL Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 445 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6LW95_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6TZ24_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6NAB6_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6RY63_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6T9L2_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete F3HNN9_PSEYM Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 156 None Unknown Any other location Nucleus Fragment F3HV48_PSEYM Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 94 None Unknown Mitochondrion Nucleus Fragment F3HH81_PSEYM Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 155 None Unknown Any other location Nucleus Fragment F3HH82_PSEYM Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 295 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Fragment F3HH80_PSEYM Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 96 None Unknown Mitochondrion Nucleus Complete S6RH94_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6VFI6_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 194 None Unknown Mitochondrion Nucleus Fragment F3DUQ1_9PSED Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 105 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete F3K9L6_PSESZ Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 100 None Unknown Mitochondrion Nucleus Fragment F3K1L5_PSESZ Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 465 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Fragment S6VHR5_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete S6T863_PSESF Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 457 AvrPtoB-E3_ubiq Unknown Mitochondrion Nucleus Fragment F3F3B2_9PSED Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. mori str. 301020 Experimentally validated effector 279 AvrPtoB-E3_ubiq Unknown Mitochondrion Nucleus Complete K2RWM9_9PSED Type III effector HopAB2 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 551 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Complete S6MS85_PSESX Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 278 AvrPtoB-E3_ubiq Unknown Any other location Nucleus Complete F3EGS9_PSESL Type III effector HopAB2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 279 AvrPtoB-E3_ubiq Unknown Mitochondrion Nucleus Complete I1V8A8_PSEYM AvrPtoB type III effector Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 537 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Fragment I1V8A6_PSEUB AvrPtoB type III effector Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 537 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Fragment I1V8A5_PSEUB AvrPtoB type III effector Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 537 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Fragment I1V8A7_PSEUB AvrPtoB type III effector Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 537 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Fragment E2MHW0_PSEUB Type III effector hopAB3 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 579 AvrPtoB-E3_ubiq Unknown Chloroplast Nucleus Complete S6WIE7_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 641 NUDIX Unknown Any other location Chloroplast,Cytoplasm Complete F3INZ6_PSESL Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 559 NUDIX Unknown Chloroplast Chloroplast Fragment F3INY7_PSESL Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 146 None Unknown Chloroplast Chloroplast Fragment S6VTM8_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 641 NUDIX Unknown Any other location Chloroplast,Cytoplasm Complete S6WCI6_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 641 NUDIX Unknown Any other location Chloroplast,Cytoplasm Complete S6KLR1_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 664 NUDIX Unknown Any other location Cytoplasm Complete S6PD40_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 664 NUDIX Unknown Any other location Cytoplasm Complete S6SUX4_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 664 NUDIX Unknown Any other location Cytoplasm Complete S6S958_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 645 HipA_N NUDIX Unknown Chloroplast Chloroplast,Cytoplasm Complete F3IZ19_PSEAP Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. aptata str. DSM 50252 Experimentally validated effector 642 NUDIX Unknown Any other location Chloroplast Fragment S6T886_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 664 NUDIX Unknown Any other location Cytoplasm Complete S6N205_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 641 NUDIX HipA_N Unknown Any other location Chloroplast,Cytoplasm Complete S6V774_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 641 NUDIX Unknown Any other location Chloroplast,Cytoplasm Complete S6NBB2_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 641 NUDIX HipA_N Unknown Any other location Chloroplast,Cytoplasm Complete F2ZR74_9PSED Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 718 NUDIX Unknown Chloroplast Chloroplast Complete S6PRH6_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 645 NUDIX HipA_N Unknown Chloroplast Chloroplast,Cytoplasm Complete S6UJP5_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 664 NUDIX Unknown Any other location Cytoplasm Complete F3H5E7_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 715 NUDIX Unknown Chloroplast Chloroplast Complete S6SVA6_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 94 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6RG14_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 569 HipA_N Unknown Any other location Chloroplast Complete F3I4T4_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 627 NUDIX HipA_N Unknown Chloroplast Chloroplast Fragment F3I4T3_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 73 None Unknown Any other location Cell,membrane,Cell,wall,Chloroplast,Nucleus Fragment S6W647_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 461 NUDIX HipA_N Unknown Any other location Chloroplast,Cytoplasm Complete S6VZ81_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 238 None Unknown Chloroplast Chloroplast Complete L7HB27_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae BRIP39023 Experimentally validated effector 701 NUDIX Unknown Chloroplast Chloroplast Complete S6PHL3_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 641 NUDIX Unknown Any other location Chloroplast,Cytoplasm Complete F3DP92_9PSED Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 490 NUDIX HipA_N Unknown Any other location Chloroplast Fragment F3DP93_9PSED Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 222 None Unknown Chloroplast Chloroplast Fragment S6L6D9_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 645 NUDIX HipA_N Unknown Chloroplast Chloroplast,Cytoplasm Complete F3K7B1_PSESZ Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 701 NUDIX Unknown Chloroplast Chloroplast Complete L7FYM3_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae BRIP34881 Experimentally validated effector 530 NUDIX Unknown Secretory pathway Chloroplast Complete L7FY77_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae BRIP34881 Experimentally validated effector 136 None Unknown Chloroplast Nucleus Complete E2MHD9_PSEUB Type III effector hopAG1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 701 NUDIX Unknown Chloroplast Chloroplast,Cytoplasm Complete S6QHI4_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 645 NUDIX HipA_N Unknown Chloroplast Chloroplast Complete S6UCZ3_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 664 NUDIX Unknown Any other location Cytoplasm Complete S6RQB8_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 645 NUDIX HipA_N Unknown Chloroplast Chloroplast,Cytoplasm Complete S6TTJ9_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 706 NUDIX Unknown Chloroplast Cytoplasm Complete F3JJA6_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 546 NUDIX HipA_N Unknown Chloroplast Chloroplast Complete K2UA38_PSESY Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 659 NUDIX Unknown Any other location Chloroplast Complete L7G5N5_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 530 NUDIX Unknown Secretory pathway Chloroplast Complete L7G754_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 136 None Unknown Chloroplast Nucleus Complete S6NU53_PSESX Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 706 NUDIX Unknown Chloroplast Cytoplasm Complete S6MTY2_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 641 NUDIX HipA_N Unknown Any other location Chloroplast,Cytoplasm Complete F3GEH5_PSESJ Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 716 NUDIX Unknown Chloroplast Chloroplast Complete S6P8E9_PSESF Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 645 NUDIX HipA_N Unknown Chloroplast Chloroplast,Cytoplasm Complete L8NBN4_PSESY Type III secretion system effector HopAG1 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 702 NUDIX Unknown Chloroplast Chloroplast Complete F3EHY2_PSESL Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 410 NUDIX Unknown Mitochondrion Chloroplast Complete F3EHY1_PSESL Type III effector HopAG1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 197 None Unknown Any other location Chloroplast,Mitochondrion,Nucleus Complete S6WLQ8_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 378 Cellulase Unknown Any other location Cell,membrane,Cell,wall Complete F3IJD5_PSESL Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 404 Cellulase Unknown Any other location Cell,membrane,Cell,wall,Cytoplasm Complete S6QBC6_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6W4Z0_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 378 Cellulase Unknown Any other location Cell,membrane,Cell,wall Complete S6KQY8_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 150 Cellulase Unknown Any other location Cytoplasm Complete S6KQT3_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 261 None Unknown Any other location Cell,membrane,Nucleus Complete T2QXA1_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 261 None Unknown Any other location Cell,membrane,Nucleus Complete S6U7H6_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 150 None Unknown Any other location Cytoplasm Complete S6R1P2_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 226 None Unknown Any other location Cell,membrane,Nucleus Complete S6R1R0_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 150 None Unknown Any other location Cytoplasm Complete S6S6Z4_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6TAB1_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 261 None Unknown Any other location Cell,membrane,Nucleus Complete S6S5S0_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 150 None Unknown Any other location Cytoplasm Complete S6MPG1_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6V5Q9_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 378 Cellulase Unknown Any other location Cell,membrane,Cell,wall Complete S6PDC7_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 127 None Unknown Any other location Cytoplasm Complete S6PJH5_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 279 Cellulase Unknown Any other location Cell,membrane,Cell,wall,Mitochondrion,Nucleus Complete S6TM05_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 150 None Unknown Any other location Cytoplasm Complete S6UMA1_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 261 None Unknown Any other location Cell,membrane,Nucleus Complete S6QVX9_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6RI57_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 261 None Unknown Any other location Cell,membrane,Nucleus Complete S6SPV3_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 150 None Unknown Any other location Cytoplasm Complete F3I4M2_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6VVL3_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 168 None Unknown Any other location Cytoplasm Fragment S6VVL6_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 126 None Unknown Any other location Mitochondrion,Nucleus Fragment S6UM58_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 108 None Unknown Any other location Nucleus Fragment S6NI12_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 378 Cellulase Unknown Any other location Cell,membrane,Cell,wall Complete F3DVN2_9PSED Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 372 Cellulase Unknown Any other location Cell,wall Complete S6MI66_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete E2MH41_PSEUB Type III effector hopAH2-1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 404 Cellulase Unknown Any other location Cell,wall Complete S6SHJ3_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 328 Cellulase Unknown Chloroplast Cell,wall,Cytoplasm Complete S6XGD9_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 378 Cellulase Unknown Any other location Cell,membrane,Cell,wall Complete S6U704_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 261 None Unknown Any other location Cell,membrane,Nucleus Complete S6VJ94_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 150 None Unknown Any other location Cytoplasm Complete S6VK55_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 392 Cellulase Unknown Any other location Cell,wall Complete S6RMR8_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6MI14_PSESX Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 395 Cellulase Unknown Any other location Cell,wall Complete S6MXX0_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 279 Cellulase Unknown Any other location Cell,membrane,Cell,wall,Mitochondrion,Nucleus Complete S6LQW5_PSESF Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 122 None Unknown Any other location Cytoplasm Complete Q87ZY0_PSESM Type III effector HopAH2-1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 404 Cellulase Unknown Any other location Cell,wall Complete S6WN04_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete F3IJD6_PSESL Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 349 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6W2D4_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6XJH4_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6KPE2_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6R741_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6SSR4_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6S258_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 350 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6SAW2_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6MWA1_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 350 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6LP99_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 69 None Unknown Any other location Nucleus Fragment S6V2V8_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6PJN5_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete F2ZNW9_9PSED Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 349 Cellulase Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6PWG0_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6UMB5_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6SXP2_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete F3I4M3_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 349 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6VN33_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 391 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6NP57_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete F3DVN1_9PSED Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 350 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6MBV9_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete E2MH40_PSEUB Type III effector hopAH2-2 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6R445_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6VAP0_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6RHH7_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 350 None Unknown Any other location Cytoplasm,Mitochondrion Complete S6U6V3_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete K2SIJ7_PSESY Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 348 Cellulase Unknown Any other location Cytoplasm,Mitochondrion Complete K2RW35_9PSED Type III effector HopAH2-2 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6MHP5_PSESX Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6LY10_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6Q5B5_PSESF Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 350 None Unknown Any other location Cytoplasm,Mitochondrion Complete Q87ZX9_PSESM Type III effector HopAH2-2 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 416 None Unknown Any other location Cytoplasm,Mitochondrion,Nucleus Complete S6R4H0_PSESF Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 69 None Unknown Chloroplast Nucleus Complete L7HBG0_PSESX Type III effector HopAI1 Unknown Plants Pseudomonas syringae BRIP39023 Experimentally validated effector 267 VRP3 Unknown Chloroplast Nucleus Complete S6MFP9_PSESF Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 69 None Unknown Chloroplast Nucleus Complete F3K7B3_PSESZ Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 107 VRP3 Unknown Chloroplast Nucleus Complete E2MHD7_PSEUB Type III effector hopAI1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 261 VRP3 Unknown Any other location Nucleus Complete S6RQD3_PSESF Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 69 None Unknown Chloroplast Nucleus Complete F3JJA3_PSESX Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 48 VRP3 Unknown Any other location None Complete K2TLM9_PSESY Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 267 VRP3 Unknown Chloroplast Nucleus Complete K2TF22_PSESY Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe037 Experimentally validated effector 267 VRP3 Unknown Chloroplast Nucleus Complete L7G5Q9_PSESX Type III effector HopAI1 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 239 VRP3 Unknown Mitochondrion Nucleus Complete L8NAF6_PSESY Type III secretion system effector HopAI1 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 267 VRP3 Unknown Chloroplast Nucleus Complete F3EHY4_PSESL Type III effector HopAI1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 75 None Unknown Chloroplast Chloroplast,Nucleus Complete E7PLP1_PSESG Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. glycinea str. race 4 Experimentally validated effector 694 None Unknown Any other location Cytoplasm Complete S6XGD0_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 814 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete S6P9K2_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 756 None Unknown Any other location Cytoplasm Complete S6WPQ9_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 814 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete S6RB11_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 756 None Unknown Any other location Cytoplasm Complete S6NIY3_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 756 None Unknown Mitochondrion Cytoplasm Complete S6W0A3_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 814 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete S6P959_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 756 None Unknown Mitochondrion Cytoplasm Complete S6PZ05_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 756 None Unknown Any other location Cytoplasm Complete F3IBE0_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 756 None Unknown Any other location Cytoplasm Complete S6M5V7_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 814 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete F3E4M8_9PSED Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 731 None Unknown Any other location Cytoplasm Complete S6M2V9_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 756 None Unknown Any other location Cytoplasm Complete G9I6Y2_PSESX Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. theae Experimentally validated effector 731 None Unknown Any other location Cytoplasm Complete S6PDJ0_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 659 None Unknown Any other location Cytoplasm Complete S6V9Q1_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 814 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete S6RXX3_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 756 None Unknown Any other location Cytoplasm Complete Q5DI80_PSESH Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 731 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete E7P815_PSESG Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. glycinea str. B076 Experimentally validated effector 694 None Unknown Any other location Cytoplasm Complete F3DLN5_9PSED Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 694 None Unknown Any other location Cytoplasm Complete K2TB31_9PSED Type III effector HopAU1 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 731 None Unknown Any other location Cytoplasm Complete S6P7Y8_PSESX Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 659 None Unknown Any other location Cytoplasm Complete S6LS72_PSESF Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 756 None Unknown Mitochondrion Cytoplasm Complete Q48BC6_PSE14 Type III effector HopAU1 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 731 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete D7I712_PSESS Type III effector HopAU1 Unknown Plants Pseudomonas savastanoi pv. savastanoi NCPPB 3335 Experimentally validated effector 731 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete S3MY93_PSESY Type III secretion system effector HopBA1 Unknown Plants Pseudomonas syringae pv. syringae SM Experimentally validated effector 239 None Unknown Chloroplast Chloroplast,Cytoplasm Complete K2TMA8_PSESY Type III effector HopBA1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 239 None Unknown Chloroplast Chloroplast,Cytoplasm,Nucleus Complete L8NIK0_PSESY Type III secretion system effector HopBA1 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 239 None Unknown Chloroplast Chloroplast,Cytoplasm Complete K2SVP1_PSESY Type III effector HopBF1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 201 None Unknown Any other location Chloroplast,Nucleus Complete K2TQ10_PSESY Full=Type III effector HopBF1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe037 Experimentally validated effector 201 None Unknown Any other location Chloroplast,Cytoplasm,Nucleus Complete F3FA61_9PSED Putative uncharacterized protein Unknown Plants Pseudomonas syringae pv. mori str. 301020 Experimentally validated effector 237 AvrPphF-ORF-2 Unknown Any other location Nucleus Complete S6WXI5_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 280 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6W1D2_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete F3IDL2_PSESL Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 144 AvrPphF-ORF-2 Unknown Any other location Chloroplast,Mitochondrion,Nucleus Complete S6Q8Z2_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6W8B3_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6WYN6_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 280 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6LSW3_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 68 AvrPphF-ORF-2 Unknown Mitochondrion Mitochondrion Complete S6SIT5_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 46 AvrPphF-ORF-2 Unknown Any other location None Complete S6QKM3_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 76 AvrPphF-ORF-2 Unknown Mitochondrion Mitochondrion Complete C0SPQ2_RALSL Type III effector protein Unknown Plants Ralstonia solanacearum (Pseudomonas solanacearum) Experimentally validated effector 292 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6TRI2_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 46 AvrPphF-ORF-2 Unknown Any other location None Complete S6LD82_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete Q83YN7_9PSED Putative uncharacterized protein Unknown Plants Pseudomonas syringae pv. delphinii Experimentally validated effector 215 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6UMQ1_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 280 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6UGZ8_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6N4S8_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6PNN4_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 254 AvrPphF-ORF-2 Unknown Chloroplast Cell,membrane,Nucleus Complete S6TPI9_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 46 AvrPphF-ORF-2 Unknown Any other location None Complete S6QZ15_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6RX62_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 68 AvrPphF-ORF-2 Unknown Mitochondrion Mitochondrion Complete F3I6I9_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6WUR7_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 76 AvrPphF-ORF-2 Unknown Mitochondrion Mitochondrion Complete S6M450_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6QMZ0_PSESF Uncharacterized protein Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 240 AvrPphF-ORF-2 Unknown Any other location Nucleus Complete F3DPZ3_9PSED Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 193 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6ME04_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6KIZ0_PSESF Uncharacterized protein Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 196 AvrPphF-ORF-2 Unknown Any other location Nucleus,Peroxisome Complete F3K8G4_PSESZ Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 46 AvrPphF-ORF-2 Unknown Any other location None Complete E2MBU5_PSEUB Type III effector hopF2 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 215 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6QKM5_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6SAH0_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 280 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6V9A2_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6VKA8_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 46 AvrPphF-ORF-2 Unknown Any other location None Complete S6RET1_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete A2BCU8_PSESH AvrPphF protein Unknown Plants Pseudomonas syringae pv. phaseolicola Experimentally validated effector 204 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete S6U3U1_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 68 AvrPphF-ORF-2 Unknown Mitochondrion Mitochondrion Complete S6TW99_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 215 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete F3JHR3_PSESX Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 203 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete E5G0U5_9PSED HopBB1 Unknown Plants Pseudomonas syringae pv. mori str. 301020 Experimentally validated effector 280 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete F3DLU3_9PSED Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete K2SIY1_9PSED Type III effector HopBB1 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 280 AvrPphF-ORF-2 Unknown Chloroplast Cell,membrane,Nucleus Complete S6MEZ2_PSESX Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 46 AvrPphF-ORF-2 Unknown Any other location None Complete S6N0S9_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 205 AvrPphF-ORF-2 Unknown Chloroplast Chloroplast,Nucleus Complete S6QKV0_PSESF Uncharacterized protein Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 337 AvrPphF-ORF-2 Unknown Any other location Nucleus Fragment S6PTV0_PSESF Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 267 AvrPphF-ORF-2 Unknown Chloroplast Cell,membrane,Nucleus Complete Q88A90_PSESM Type III effector HopF2 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 204 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete Q8XRK9_RALSO Probable avrpphf family type III effector protein Unknown Plants Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) Experimentally validated effector 350 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete Q48G35_PSE14 Type III effector HopF3 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 198 AvrPphF-ORF-2 Unknown Chloroplast Nucleus Complete E7PP21_PSESG Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. glycinea str. race 4 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete S6V0I9_PSESF Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete S6NU66_PSESF Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete E2MN40_PSEUB Type III effector hopH1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete S6WR51_PSESF Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete E7PE48_PSESG Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. glycinea str. B076 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete K2T2B3_9PSED Type III effector HopH1 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete F3GCB9_PSESJ Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete Q4ZV89_PSEU2 Type III effector HopH1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 218 Peptidase_M91 Unknown Any other location Nucleus Complete F3DC82_9PSED Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete E7PJ45_PSESG Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. glycinea str. race 4 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete A3QQZ4_PSEYM HopI1 Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 296 None Unknown Any other location Nucleus Fragment S6WYL2_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 466 DnaJ Unknown Chloroplast Golgi Complete Q8RP09_PSEYM Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 432 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete A3QQZ9_PSEYM HopI1 Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 276 None Unknown Any other location Nucleus Fragment A3QQZ8_PSEYM HopI1 Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 372 None Unknown Any other location Nucleus Fragment F3ICX9_PSESL Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 488 DnaJ Unknown Chloroplast Golgi Complete S6VVG0_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 418 DnaJ Unknown Chloroplast Golgi Complete S6MCV7_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 316 DnaJ Unknown Any other location Endoplasmic Complete S6S5G9_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 115 DnaJ Unknown Any other location Endoplasmic Fragment S6TJJ7_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 152 None Unknown Any other location Nucleus Fragment S6T7X9_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 316 DnaJ Unknown Any other location Endoplasmic Complete A3QQZ7_PSEUB HopI1 Unknown Plants Pseudomonas syringae pv. tomato Experimentally validated effector 296 None Unknown Any other location Nucleus Fragment F3FCB6_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. japonica str. M301072 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete S6QLK2_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 377 None Unknown Chloroplast Nucleus Complete S6RZ92_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 73 DnaJ Unknown Any other location Endoplasmic Complete F3IXN2_PSEAP Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. aptata str. DSM 50252 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete S6SKK8_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 316 DnaJ Unknown Any other location Endoplasmic Complete S6KFY3_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 332 None Unknown Chloroplast Nucleus Fragment S6KIT2_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 168 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Fragment S6UH09_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 226 None Unknown Chloroplast Nucleus Fragment S6VL80_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 122 DnaJ Unknown Chloroplast Endoplasmic Fragment S6NMW5_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 450 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete S6V672_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 164 DnaJ Unknown Chloroplast Endoplasmic Fragment S6UXM9_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 158 None Unknown Any other location Nucleus Fragment S6PMM3_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 456 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete F3H9A0_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 220 None Unknown Chloroplast Nucleus Fragment F3HAC6_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 101 None Unknown Any other location Nucleus Fragment F3HM16_PSEYM Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 358 DnaJ Unknown Chloroplast Endoplasmic Complete F3H9R5_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 120 None Unknown Chloroplast Mitochondrion Fragment F3H9H3_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae Cit 7 Experimentally validated effector 122 DnaJ Unknown Any other location Endoplasmic Fragment S6T8D1_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 316 DnaJ Unknown Any other location Endoplasmic Complete F3IAE4_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 128 DnaJ Unknown Chloroplast Endoplasmic Fragment S6SMP5_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 316 DnaJ Unknown Any other location Endoplasmic Complete L7H7N2_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae BRIP39023 Experimentally validated effector 338 DnaJ Unknown Chloroplast Endoplasmic Complete A3QR01_PSESY HopI1 Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 338 DnaJ Unknown Chloroplast Endoplasmic Complete A3QR00_PSESY HopI1 Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete S6PCY1_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 181 None Unknown Chloroplast Nucleus Fragment S6PCJ5_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 136 DnaJ Unknown Chloroplast Endoplasmic Fragment F3DRA6_9PSED Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 117 DnaJ Unknown Chloroplast Endoplasmic Fragment F3E510_9PSED Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 213 None Unknown Chloroplast Nucleus Fragment S3MPF6_PSESY Type III secretion system effector HopI1 Unknown Plants Pseudomonas syringae pv. syringae SM Experimentally validated effector 337 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete S6LP39_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 456 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete F3K2L5_PSESZ Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete L7G7S4_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae BRIP34881 Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete E2M7R3_PSEUB Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 488 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete S6X2N9_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 123 DnaJ Unknown Chloroplast Endoplasmic Fragment S6YAX9_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 230 None Unknown Chloroplast Nucleus Fragment S6V0J7_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 149 None Unknown Any other location Nucleus Fragment S6V0I7_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 182 DnaJ Unknown Chloroplast Endoplasmic Fragment S6Q087_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 456 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete E7PAH0_PSESG Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. glycinea str. B076 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete S6VA78_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 132 DnaJ Unknown Chloroplast Endoplasmic Fragment S6VCW1_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 150 None Unknown Any other location Chloroplast,Nucleus Fragment F3JCH0_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. aceris str. M302273 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete K2T6D7_PSESY Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete K2T0Q8_PSESY Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe037 Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete F3ERI6_9PSED Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. mori str. 301020 Experimentally validated effector 336 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete L7GFE0_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete S6M894_PSESX Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 456 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete S6LTN2_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 450 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete F3G4A3_PSESJ Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete S6NLN8_PSESF Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 494 DnaJ Unknown Chloroplast Golgi,apparatus,Nucleus Complete L8NBC9_PSESY Type III secretion system effector HopI1 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 337 DnaJ Unknown Chloroplast Endoplasmic Complete F3EHT9_PSESL Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M301315 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete Q4ZNB6_PSEU2 Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete Q48DQ9_PSE14 Type III effector HopI1 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete D7I5K5_PSESS Type III effector HopI1 Unknown Plants Pseudomonas savastanoi pv. savastanoi NCPPB 3335 Experimentally validated effector 336 DnaJ Unknown Chloroplast Endoplasmic Complete F3IRM7_PSESL Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 96 ART Unknown Any other location Nucleus Complete F3IP81_PSESL Type III effector HopO1-3 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 44 None Unknown Any other location None Fragment F3IP83_PSESL Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 202 ART Unknown Any other location Nucleus Complete S6L2K1_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 177 ART Unknown Any other location Nucleus Complete S6RUH9_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 177 ART Unknown Any other location Nucleus Complete S6T275_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 202 ART Unknown Any other location Nucleus Complete S6SJK7_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 202 ART Unknown Any other location Nucleus Complete S6TWF9_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 202 ART Unknown Any other location Nucleus Complete F3HQV5_PSEYM Type III effector HopO1-1 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 209 ART Unknown Any other location Chloroplast,Nucleus Complete S6SYZ9_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 202 ART Unknown Any other location Nucleus Complete S6U7T4_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 177 ART Unknown Any other location Nucleus Complete F3K8F7_PSESZ Type III effector HopO1-1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 209 ART Unknown Any other location Chloroplast,Nucleus Complete E2M7K0_PSEUB HopO1-3 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 301 ART Unknown Chloroplast Nucleus Complete E2MMY4_PSEUB Type III effector HopO1-1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 290 ART Unknown Chloroplast Nucleus Complete E2M7K2_PSEUB HopO1-2 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 298 ART Unknown Chloroplast Nucleus Complete S6V9Z3_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 214 ART Unknown Any other location Nucleus Complete S6V7U9_PSESF Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 177 ART Unknown Any other location Nucleus Complete F3DLN9_9PSED Type III effector HopO1-1 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 202 ART Unknown Any other location Chloroplast,Nucleus Complete K2T9V0_9PSED Type III effector HopO1 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 302 ART Unknown Chloroplast Nucleus Complete Q87WF6_PSESM Type III effector HopO1-2 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 298 ART Unknown Chloroplast Nucleus Complete Q88BP8_PSESM Type III effector HopO1-1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 283 ART Unknown Chloroplast Nucleus Complete Q87WF8_PSESM Type III effector HopO1-3 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 168 ART Unknown Chloroplast Nucleus Complete S6WWE8_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete F3IRM5_PSESL Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6VSP2_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6MIA6_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6T0U0_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6U722_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6QM45_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6TTT7_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6KHQ8_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6VVP0_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6NMA7_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 113 None Unknown Mitochondrion Nucleus Complete S6V5H5_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6QMM5_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6RSQ3_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete F3I1T0_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6TY35_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6QNE6_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6KEG5_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete E2M7J7_PSEUB HopS2 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 177 None Unknown Chloroplast Nucleus Complete S6SGU1_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6Y9X1_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6TXQ4_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6RDL2_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete S6WC57_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete K2SG17_9PSED Type III effector HopS2 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 177 None Unknown Mitochondrion Nucleus Complete S6NLV3_PSESX Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 95 None Unknown Chloroplast Nucleus Complete S6MAK8_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 113 None Unknown Mitochondrion Nucleus Complete S6PTI4_PSESF Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 95 None Unknown Chloroplast Chloroplast,Nucleus Complete Q87WG2_PSESM Type III effector HopS2 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 177 None Unknown Chloroplast Nucleus Complete F3IP82_PSESL Type III effector HopT1-2 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 389 None Unknown Any other location Chloroplast,Cytoplasm Complete S6LB25_PSESF Type III effector HopT1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 382 None Unknown Any other location Chloroplast Complete S6RVK9_PSESF Type III effector HopT1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 382 None Unknown Any other location Chloroplast Complete S6T3C5_PSESF Type III effector HopT1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 382 None Unknown Any other location Chloroplast Complete F3HQV6_PSEYM Type III effector HopT1-1 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 379 None Unknown Any other location Chloroplast,Nucleus Complete S6TY89_PSESF Type III effector HopT1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 382 None Unknown Any other location Chloroplast Complete F3K8F8_PSESZ Type III effector HopT1-1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 379 None Unknown Any other location Chloroplast,Nucleus Complete E2M7K1_PSEUB HopT1-2 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 389 None Unknown Any other location Chloroplast Complete E2MMY3_PSEUB Type III effector hopT1-1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 382 None Unknown Any other location Chloroplast,Nucleus Complete S6V1A8_PSESF Type III effector HopT1-2 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 382 None Unknown Any other location Chloroplast Complete F3DLP0_9PSED Type III effector HopT1-1 Unknown Plants Pseudomonas syringae pv. aesculi str. 0893_23 Experimentally validated effector 391 None Unknown Any other location Chloroplast,Nucleus Complete Q88BP7_PSESM Type III effector HopT1-1 Unknown Plants Pseudomonas syringae pv. tomato (strain DC3000) Experimentally validated effector 378 None Unknown Any other location Chloroplast,Nucleus Complete HOPW2_PSEYM Putative truncated effector protein hopW1-2 Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 240 HopW1-1 Unknown Chloroplast Nucleus Complete Q83YM6_PSESZ HopX1 Unknown Plants Pseudomonas syringae pv. tabaci Experimentally validated effector 380 None Unknown Chloroplast Nucleus Complete E7PKW2_PSESG Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. glycinea str. race 4 Experimentally validated effector 302 None Unknown Any other location Chloroplast Complete S6LTA9_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion,Nucleus Complete S6TMV4_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion,Nucleus Complete S6NZ98_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 307 None Unknown Mitochondrion Cytoplasm Complete S6RWX0_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion,Nucleus Complete S6T6K6_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion,Nucleus Complete F3HEJ8_PSEYM Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. maculicola str. ES4326 Experimentally validated effector 289 None Unknown Any other location Cell,membrane,Cytoplasm Complete S6R7B7_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion,Nucleus Complete S6WZS6_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 307 None Unknown Mitochondrion Cytoplasm Complete F3JWC8_PSESZ Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. tabaci str. ATCC 11528 Experimentally validated effector 302 None Unknown Any other location Chloroplast Complete S6VK87_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion,Nucleus Complete S6SR13_PSESF Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 307 None Unknown Mitochondrion Cytoplasm Complete E7P9A8_PSESG Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. glycinea str. B076 Experimentally validated effector 302 None Unknown Any other location Chloroplast Complete K2TG58_PSESY Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe013 Experimentally validated effector 382 None Unknown Chloroplast Nucleus Complete K2T8E4_PSESY Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. avellanae str. ISPaVe037 Experimentally validated effector 382 None Unknown Chloroplast Nucleus Complete S6MUA0_PSESX Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 221 None Unknown Mitochondrion Mitochondrion Complete F3G208_PSESJ Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 156 None Unknown Mitochondrion Cytoplasm,Nucleus Fragment F3G207_PSESJ Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. pisi str. 1704B Experimentally validated effector 144 None Unknown Any other location Nucleus Fragment Q4ZX48_PSEU2 Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 382 None Unknown Chloroplast Nucleus Complete Q48M17_PSE14 Type III effector HopX1 Unknown Plants Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Experimentally validated effector 380 None Unknown Chloroplast Nucleus Complete S6Y1L0_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete F3INB8_PSESL Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. lachrymans str. M302278 Experimentally validated effector 287 HrpA_pilin Unknown Chloroplast Nucleus Complete S6NQM6_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6VVK0_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 286 HrpA_pilin Unknown Chloroplast Nucleus Complete S6M8I2_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6MF62_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19098 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete S6UEX7_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6RDP6_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6REC0_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18804 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete S6T098_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18883 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete S6QPH8_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6TH94_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6TRU7_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19099 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete S6MA81_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6URM0_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6PQW2_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 286 HrpA_pilin Unknown Chloroplast Nucleus Complete F2ZE69_9PSED Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. oryzae str. 1_6 Experimentally validated effector 287 HrpA_pilin Unknown Chloroplast Nucleus Complete S6TP69_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete S6V2W4_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19095 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6PIN0_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6RQ62_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6RR54_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19100 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete F3HYS4_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6T4Z4_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19096 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6QEH6_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete F3DX70_9PSED Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. morsprunorum str. M302280 Experimentally validated effector 287 HrpA_pilin Unknown Chloroplast Nucleus Complete S6KMK5_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete E2MIT6_PSEUB Type III effector hopY1 Unknown Plants Pseudomonas syringae pv. tomato T1 Experimentally validated effector 287 HrpA_pilin Unknown Chloroplast Nucleus Complete S6S459_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6YE11_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6VC70_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete S6V3K2_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19094 Experimentally validated effector 86 HrpA_pilin Unknown Chloroplast Chloroplast Complete S6R9W7_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6WD38_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18807 Experimentally validated effector 56 HrpA_pilin Unknown Mitochondrion Nucleus Complete K2TL73_9PSED Type III effector HopY1 Unknown Plants Pseudomonas avellanae BPIC 631 Experimentally validated effector 287 HrpA_pilin Unknown Chloroplast Nucleus Complete S6MI39_PSESX Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 310 HrpA_pilin Unknown Any other location Nucleus Complete S6LXE4_PSESF Type III effector HopY1 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 286 HrpA_pilin Unknown Chloroplast Nucleus Complete Q8RP13_PSEYM Type III effector HopPmaD Unknown Plants Pseudomonas syringae pv. maculicola Experimentally validated effector 260 YopJ Unknown Mitochondrion Chloroplast Complete Q9F3T5_PSESJ Type III effector HopZ2 Unknown Plants Pseudomonas syringae pv. pisi Experimentally validated effector 362 YopJ Unknown Any other location Nucleus Complete A0FDW2_PSESL Type III effector HopZ2 Unknown Plants Pseudomonas syringae pv. lachrymans Experimentally validated effector 362 YopJ Unknown Any other location Nucleus Complete A0FDX1_PSESX Type III effector HopZ2 Unknown Plants Pseudomonas syringae pv. aceris Experimentally validated effector 362 YopJ Unknown Any other location Nucleus Complete A0FDW6_9PSED Type III effector HopZ2 Unknown Plants Pseudomonas syringae pv. coronafaciens Experimentally validated effector 362 YopJ Unknown Any other location Nucleus Complete A0FDW7_PSESY Type III effector HopZ2 Unknown Plants Pseudomonas syringae pv. syringae Experimentally validated effector 362 YopJ Unknown Any other location Nucleus Complete A0FDW8_PSEYS Type III effector HopZ2 Unknown Plants Pseudomonas syringae pv. sesami Experimentally validated effector 362 YopJ Unknown Any other location Nucleus Complete S6Y0J1_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18801 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6X2J7_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19097 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete F3FD65_PSESX Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. japonica str. M301072 Experimentally validated effector 325 YopJ Unknown Mitochondrion Chloroplast Complete F3IUX1_PSEAP Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. aptata str. DSM 50252 Experimentally validated effector 144 YopJ Unknown Any other location Chloroplast,Nucleus Fragment S6QY55_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 9855 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete F3IUX2_PSEAP Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. aptata str. DSM 50252 Experimentally validated effector 152 YopJ Unknown Any other location Nucleus Fragment S6M9E6_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19073 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6W1I7_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19079 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6ND38_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19072 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6PJQ5_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19104 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete F3HZ87_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae str. M302091 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6P5Z6_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 18886 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6LZ11_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19103 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete L7GDE0_PSESX Type III effector HopZ3 Unknown Plants Pseudomonas syringae BRIP34881 Experimentally validated effector 299 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6T042_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19070 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6YD05_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19101 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6RC49_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19102 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete L7GBX3_PSESX Type III effector HopZ3 Unknown Plants Pseudomonas syringae BRIP34876 Experimentally validated effector 299 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6NPQ8_PSESX Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. theae ICMP 3923 Experimentally validated effector 341 YopJ Unknown Chloroplast Chloroplast Complete S6LWX9_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19071 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete S6Q4H9_PSESF Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. actinidiae ICMP 19068 Experimentally validated effector 407 YopJ Unknown Any other location Chloroplast,Nucleus Complete L8NM83_PSESY Type III secretion system effector HopZ3 Unknown Plants Pseudomonas syringae pv. syringae B64 Experimentally validated effector 411 YopJ Unknown Chloroplast Chloroplast,Nucleus Complete Q4ZX47_PSEU2 Type III effector HopZ3 Unknown Plants Pseudomonas syringae pv. syringae (strain B728a) Experimentally validated effector 411 YopJ Unknown Chloroplast Chloroplast,Nucleus Complete BOPA_BURMA Effector protein BopA Plays a role in mediating bacterial evasion from the host autophagic pathway. Animals and Humans Burkholderia mallei (strain ATCC 23344) Experimentally validated effector 512 SicP-binding Unknown Mitochondrion Golgi Complete G9L9K6_XANCE Outer protein D Unknown Plants Xanthomonas campestris pv. campestris Experimentally validated effector 801 Ulp1 protease family,C-terminal catalytic domain Unknown Any other location Nucleus Complete