Accession: Y54E5B.2 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = Y54E5B.2 (Len=861)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (Y54E5B.2, Len=861):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MDELEDNPCLLDHLIQSKIAEKHLLSGKIITCAKFDEKYSKCAENQIIEEFPEHIIGCKLFKKEKKIITVTSRNSLTIRI 80  
WD40-rpts                                        (____________________WD 1____________________)

Query       81 SSNLSVLSKIQCDYFATSICSLIIGNSAESCHVYFGSVIGELIDWKPHEDEKPIMRKGHKGMIFSIVTDSTRIFTISDDR 160 
WD40-rpts         (___________________WD 2__________________)   (________________WD 3__________

Query      161 TIRMWPIDDRESGPLCTVFGHTARPFAICVDPINYRIYTGGIEQTLFCWKYDERSIDLRQKIAIPIGVIQKISKIDDSTL 240 
WD40-rpts      _____)     (_________________WD 4________________)     (________________WD 5____

Query      241 AISSQNGDLLEIHVEQQSLKSKIVILKDDLMNFANLNGKLVILTADNELILFESDAMLRIIFRCTNIKHMTSSDDSVVAW 320 
WD40-rpts      ____________)             (________________WD 6_______________)                 

Query      321 HQNTWIVITTSSVHRLKLSMNIISATCHASYVAIKTIDGIIHVYNFADVENIRCLKRFRAQNASMIPAVISVVHDNLLVI 400 
WD40-rpts          (__________________WD 7_________________)(____________________WD 8__________

Query      401 GTTHGELYHVDLDEPNDDIRLSLSRSTSFELFGGKEVTCIRSIPNSSIFMTLGKTGIWSTIRLIRGGTTNYEMEVMNFRS 480 
WD40-rpts      __________)            (__________________WD 9__________________)(______________

Query      481 FSTSSRMAWPSKFIEWKGNLLIVGFYGTSLIIWNSTTNLPIFETYCGGGHRIWQLNGSEENKFNFDFIRDSQLCRQKIDF 560 
WD40-rpts      ________WD10_____________________)(___________________WD11__________________)  (

Query      561 LSKNYWISNAHSSPIVAASGSSNYLVTVSLDGHLSISDGNLKRILTIFVGENLLCTDIYDEADENGTVYILTGGGKSKLS 640 
WD40-rpts      _________________WD12________________)   (___________________WD13_______________

Query      641 IIWFNSLEFKNSSVFSLRHVSRPDEGRVVAVKTCRIAQKTYFIASYSSGTIEVFGGISLESVFSIEIEDSLGIAAKMDYS 720 
WD40-rpts      ___)              (________________WD14_______________)  (_________________WD15_

Query      721 KSQLVVGTSGSYILTYDLLEDGVLREKQRVKLPDRSGVTSISYIPEDDSTIIGCDSGHVYKYHTSTITKIHSHLSTVVGI 800 
WD40-rpts      ________________)       (_________________WD16________________)(________________

Query      801 VVTDRNRIHTVSLDCAVVTSSMSPSATSSRIPTIIGMPNGMVKTGESTLVVVGDGIQSIEC 861 
WD40-rpts      _WD17________________)

17 WD40-repeats found in QUERY=Y54E5B.2 (Len=861):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  3    35-80       6.46  381.66  0.00045        5.0%     54.76
  WD 2:  Seg  7    84-126      5.77  352.91  0.00109       15.0%     52.63
  WD 3:  Seg 11   130-166      7.07  406.56  0.00021       27.5%     46.06
  WD 4:  Seg 15   172-210      8.53  467.18  3.1e-05       25.0%     51.58
  WD 5:  Seg 19   216-253      4.15  286.07  0.00866       12.5%     53.93
  WD 6:  Seg 24   267-303      5.87  357.25  0.00095        7.5%     41.65
  WD 7:  Seg 30   325-365      6.25  372.89  0.00059       20.0%     50.53
  WD 8:  Seg 33   366-411      6.10  366.65  0.00071       20.0%     51.67
  WD 9:  Seg 38   424-465      3.80  271.72  0.01349       15.0%     40.92
  WD10:  Seg 42   466-514      5.96  360.81  0.00085       17.5%     46.77
  WD11:  Seg 46   515-557      4.23  289.48  0.00779       12.5%     54.32
  WD12:  Seg 50   560-598      6.92  400.69  0.00025       20.0%     44.95
  WD13:  Seg 54   602-644      3.53  260.51  0.01905       17.5%     35.47
  WD14:  Seg 58   659-695      5.84  355.87  0.00100       22.5%     33.15
  WD15:  Seg 61   698-737      5.05  323.25  0.00274       17.5%     33.97
  WD16:  Seg 65   745-783      7.18  411.45  0.00018       27.5%     50.46
  WD17:  Seg 69   784-822      5.06  323.57  0.00271       10.0%     42.86

Multiple sequence alignment of 17 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   35-80     FD---E-----KYSKCAENQIIEEFPEHII----GCKLFK-K------EK----KIITVTSRNSLTIRI
   WD 2   84-126    -L---S-----VL------SKIQCDYFATSICSLIIGNSA-E------SC----HVYFGSVIGELIDWK
   WD 3  130-166    -D---E-----KP------IMRKGHKGMIF----SI--VT-D------ST----RIFTISDDRTIRMWP
   WD 4  172-210    -S---G-----PL------CTVFGHTARPF----AICVDP-I------NY----RIYTGGIEQTLFCWK
   WD 5  216-253    -I---D-----LR------QKIAIPIGVIQ----KISKID-D------S-----TLAISSQNGDLLEIH
   WD 6  267-303    KD---D--------------LMNFANLNGK----LVILTA-D------NE----LILFESDAMLRIIFR
   WD 7  325-365    -W---I-----VI------TTSSVHRLKLS--MNIISATC-H------AS----YVAIKTIDGIIHVYN
   WD 8  366-411    FA---DVENIRCL------KRFRAQNASMI----PAVISVVH------DN----LLVIGTTHGELYHVD
   WD 9  424-465    -S---R-----ST------SFELFGGKEVT----CIRSIP-N------SS-IFMTLGKTGIWSTIRLIR
   WD10  466-514    GG---T--TNYEM------EVMNFRSFSTS----SRMAWP-SKFIEWKGN----LLIVGFYGTSLIIWN
   WD11  515-557    STTNLP-----IF------ETYCGGGHRIW----QLNGSE-E------NK----FNFDFIRDSQLCRQK
   WD12  560-598    FL---S------K------NYWISNAHSSP----IVAASG-S------SN----YLVTVSLDGHLSISD
   WD13  602-644    -K---R-----IL------TIFVGENLLCT----DIYDEA-D------ENGTVYILTGGGKSKLSIIWF
   WD14  659-695    -----H-----VS------RPDEGRVVAVK----TCRIAQ-K------TY----FIASYS-SGTIEVFG
   WD15  698-737    SL---E-----SV------FSIEIEDSLGI----AAKMDY-S------KS----QLVVGTSGSYILTYD
   WD16  745-783    -R---E-----KQ------RVKLPDRSGVT----SISYIP-E------DD----STIIGCDSGHVYKYH
   WD17  784-822    T----S-----TI------TKIHSHLSTVV----GIVVTD-R------NR----IHTVSLDCAVVTSSM

   WD40 Template    TG---E-----CL------RTLSGHTSGVT----SVSFSP-D------GK----RLVSGSEDGTIKVWD