Accession: Y54F10AM.10 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = Y54F10AM.10 (Len=1322)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (Y54F10AM.10, Len=1322):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MVEVAPAGTKSPALSVPVVIWGPKPPENKICAIRVLPDGATIITGAENGHIIIWKLAEGLMPKQLMIGHSQKITAISQTT 80  
WD40-rpts                          (_______________WD 1______________)(____________________WD 2

Query       81 NTPTNTRFVSASADGRVCLWEIQDGRCIDSTSSIAIHRYIYPYTYKSSRHTRATRLFCIGDYSDIQVMDPQDLTVVFSIS 160 
WD40-rpts      ____________________)   (____________________WD 3___________________)   (_______

Query      161 SRVEPDWISCFTIISHPEKEDQLIGMTLSGMMKVWTLTELEKKDPATSLYEDESKRLEIQHIRSVSYICSTRRMLLIIAS 240 
WD40-rpts      ____________WD 4___________________)(_______________________WD 5________________

Query      241 TCWMIIDMDDLSTVVFHKNEITTKRCVAGYLTDLDKVTIGYTDESIHVFQLPIESLQKEGVPPVVANNRPTSNYFDQPNP 320 
WD40-rpts      ______)(___________________WD 6__________________)                             (

Query      321 FIVATVNGVQEHSRSCLNDVQFAFLPYNSSNSLESSSSSYEKRRFSVVRSSRRDGSVLNSDAVCCSLFVTSQGKLFLGRS 400 
WD40-rpts      _____________________WD 7____________________)            (_________________WD 8

Query      401 DGVIVMTYACETLARQWLRVPAERATSRILTGHDAAVRSMFYPFEHDTRYDPQYFVSGSDDFSVIVWNINSGTRIHRFTV 480 
WD40-rpts      _________________)     (____________________WD 9___________________)   (________

Query      481 HGGPVKSFMLPPSNCSKQVTKCIASLAADNTIALLNIRDSKCMLLASRHPFPIIQVKWRPLDDFMLVKLADGSVYVWQME 560 
WD40-rpts      ____________WD10___________________)   (_________________WD11________________)(_

Query      561 TANLDRIATGLLAEDIMTACDEQIGVEEGTDETSAHHAVQLIRALKNKNMEAVKQKVVGGSVSGAATPSSHHELPTNCGT 640 
WD40-rpts      ________________WD12_________________)(_____________________WD13________________

Query      641 AVQLGSPMSILPLPGCAQGAHLVQFEISALIAGILHLDSSAEAPEGKTTAQKLDAAAAAGASDSATGLSRKLTWQFEANL 720 
WD40-rpts      _____)(_________________WD14________________)                                   

Query      721 YLDVARLMLSMLHAWCLDEDMDEVCDKRLSLHRPRHQVYFGNVSRQGELSVSLPTRFAADFESFCKKSRWQASHSLNTSH 800 
WD40-rpts                                  (___________________WD15__________________)         

Query      801 LLAVIATSNTLMAMKNSALQLAKIRKSVVEQNQSTIHQPDRQQIKQGWSLVAALHCVLLPDHVRPRSSYAPPSIEMLVRR 880 
WD40-rpts                                                                                      

Query      881 WQDSCLEIREAAQALLIRELTRLGAEGRRRLIESWTPFLPPLLDDSLSIFGSKLQSSVPTVQPSAPAPPIPPRTKNAPPD 960 
WD40-rpts                                                                                      

Query      961 VEPVRGSEPPTAEGGEAGIQQVRRNQATSIILLGVIGSQFGDELNRADLTRATAVSLLELLVAAPSNLIPVHSPLRRAAI 1040
WD40-rpts                                                                                      

Query     1041 DLLGRGFVHWEPHLEISKVVLGLLDLASNNEKPGTQRRITGAPLNAIEDAARTSRQALSLIALARPPALITSLSMEVARY 1120
WD40-rpts                                                                                      

Query     1121 NAAAQHQTIQHTVVSPLLKSRSEVLRIIEELCEKRYNDIIAMLLPVGDILVHCLDITILKHKSMSEVFPPIVKFNMVAYC 1200
WD40-rpts                                                                   (________________WD

Query     1201 STSKRVAFGGKNGTCVVHELRATKTHSLPSHNGPIAAVAFSEDGKYLATYGAEDGKINFFQTSQSFLGMGQAQLKLTKSQ 1280
WD40-rpts      16________________)  (_________________WD17_________________)                   

Query     1281 PAPTVSVPTTPSGTSFRPRLVWINSKSLTLMLPEGREQRFSL 1322
WD40-rpts

17 WD40-repeats found in QUERY=Y54F10AM.10 (Len=1322):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  3    21-55       7.07  406.80  0.00020       22.5%     46.76
  WD 2:  Seg  6    56-101      7.28  415.53  0.00016       35.0%     47.61
  WD 3:  Seg 10   105-149      4.32  293.28  0.00693       20.0%     50.62
  WD 4:  Seg 14   153-196      6.11  367.01  0.00070       22.5%     55.27
  WD 5:  Seg 18   197-247      3.48  258.37  0.02034       15.0%     35.99
  WD 6:  Seg 22   248-290      4.89  316.73  0.00335       22.5%     38.04
  WD 7:  Seg 28   320-366      3.75  269.53  0.01443       15.0%     39.08
  WD 8:  Seg 33   379-418      6.14  368.27  0.00068       12.5%     46.22
  WD 9:  Seg 37   424-468      7.20  412.15  0.00017       35.0%     44.34
  WD10:  Seg 40   472-516      6.37  377.86  0.00050       25.0%     55.52
  WD11:  Seg 44   520-558      8.49  465.18  3.3e-05       22.5%     53.40
  WD12:  Seg 48   559-598      5.55  344.01  0.00144       10.0%     33.29
  WD13:  Seg 51   599-646      6.01  363.05  0.00080        7.5%      6.00
  WD14:  Seg 54   647-685      4.00  279.76  0.01052       15.0%     19.68
  WD15:  Seg 57   749-791      3.85  273.55  0.01275       12.5%     12.04
  WD16:  Seg 63  1182-1219     7.15  410.01  0.00019       17.5%     41.52
  WD17:  Seg 66  1222-1261     7.74  434.25  8.7e-05       32.5%     50.59

Multiple sequence alignment of 17 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1   21-55     WG---------------------------PKPPE-----NKIC----AIR---VL------PDG------A--------TIITGA-ENGHIIIWK
   WD 2   56-101    LAEG--------LMPKQ-----------LMIGHS-----QKIT----AISQTTNT------PTN------T--------RFVSAS-ADGRVCLWE
   WD 3  105-149    -GRC--------I---D-----------STSSIA-----IHRY----IYP---YTYKSSRHTRA------T--------RLFCIG-DYSDIQVMD
   WD 4  153-196    -LTV--------V---F-----------SISSRVEPDWISCFT----IIS---HP------EKE------D--------QLIGMT-LSGMMKVWT
   WD 5  197-247    LTEL--------E---KKDPATSLYEDESKRLEI-----QHIR----SVS---YI------CST------R--------RMLLII-ASTCWMIID
   WD 6  248-290    -MDD--------L---S-----------TVVFHK-----NEITTKRCVAG---YL------TDL------D--------KVTIGY-TDESIHVFQ
   WD 7  320-366    -PFI--------V---A-----------TVNGVQ-----EHSR----SCL---ND------VQF------AFLPYNSSNSLESSS-SSYEKRRFS
   WD 8  379-418    NSDA--------V---C-----------CSLFVT-----SQGK----LFL---GR------SDG------V--------IVMTYA-CETLARQWL
   WD 9  424-468    -RAT--------S---R-----------ILTGHD-----AAVR----SMF---YPFEHDTRYDP------Q--------YFVSGS-DDFSVIVWN
   WD10  472-516    -GTR--------I---H-----------RFTVHG-----GPVK----SFM---LP------PSNCSKQVTK--------CIASLA-ADNTIALLN
   WD11  520-558    -SKC--------M---L-----------LASRHP-----FPII----QVK---WR------PLD------D--------FMLVKL-ADGSVYVWQ
   WD12  559-598    META--------N---L-----------DRIATG-----LLAE----DIM---TA------CDE------Q--------IGVEEG-TDETSAHHA
   WD13  599-646    VQLIRALKNKNME---A-----------VKQKVV-----GGSV----SGA---AT------PSS------H--------HELPTN-CGTAVQLGS
   WD14  647-685    -PMS--------I---L-----------PLPGCA-----QGAH----LVQ---FE------ISA------L--------IAGILH-LDSSAEAPE
   WD15  749-791    LSLH--------RPRHQ-----------VYFGNV-----SRQG----ELS---VS------LPT------R--------FAADFE-SFCKKSRWQ
   WD16 1182-1219   --KS--------M---S-----------EVFPPI-----VKFN----MVA---YC------STS------K--------RVAFGG-KNGTCVVHE
   WD17 1222-1261   -ATK--------T---H-----------SLPSHN-----GPIA----AVA---FS------EDG------K--------YLATYGAEDGKINFFQ

   WD40 Template    TGEC--------L---R-----------TLSGHT-----SGVT----SVS---FS------PDG------K--------RLVSGS-EDGTIKVWD