Accession: ENSDARP00000014740 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSDARP00000014740 (Len=1647)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSDARP00000014740, Len=1647):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 RIRPQLAKEKIEGCHICTFVMPDEPQVVLGKDKAFTYDYVFDMDSTQDNIYSNCTEKLIEGCFEGYNATIFAYGQTGSGK 80  
WD40-rpts                                                                                      

Query       81 TYTMGTGFDVAIPDEDLGIIPRAVTHLFKGIEQRRQQAAEQSRPVPEFKISAQFLELYNEEVLDLFDTTRDMESRKQKSH 160 
WD40-rpts                                                                                      

Query      161 IKIHEDASGGIYTVGVTTRNVSSEAEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHICQIRVCAPADSDNETDNRLA 240 
WD40-rpts                                                                                      

Query      241 GSSSEMEEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDRSKRSTHVPYRDSKLTRLLQD 320 
WD40-rpts                                                                                      

Query      321 SLGGNSRTVMIACISPSDQDFMETLNTLKYANRARNIKNKVMVNQDRASQQISALRTEIARLQMELMEYRTGKRMVGEDG 400 
WD40-rpts                                                                                      

Query      401 LESINDMFHENSMLQVENNNLRMRVKAMQEAIDAQGARLTQLLSQQANQLLARAGEGSEEIGNMIQNYIKEIEDLRAKLL 480 
WD40-rpts                                                                                      

Query      481 ESEAVNENLRRNLTRASSRPQFYGASGSFSTALLGPDPSQETSDIIEIAKKDLEKLKRREKKKKKRLQQLLADKRALFSC 560 
WD40-rpts                                                                                      

Query      561 SANKDETQEDGEQKTEKEQSESTNQEPEMEASDREEGDGEEDEEDVEEEEMEAEESSEETDSELDEKEDFQADLANITCE 640 
WD40-rpts                                                                                      

Query      641 IAIKQKLIDELENSQRRLHTLKQQYEHKLMMLQSKIRDTQLERDRVLHSMGSVESCSEDKTKRIKAEYEKKLSVMNKELQ 720 
WD40-rpts                                                                                      

Query      721 KLQAAQKEHARLLKNQSQYEKQLKKLQLDLTEMKKTKVRLMKQMKEQQEKSRMAESRRNREIATLKKDQRKQEHQLKLLE 800 
WD40-rpts                                                                                      

Query      801 AQKRQQELILRRKTEEVTALRRQVRPISGKVTRKANLSEPNFDLSHRPPAGRTYGSGAQTNTIIYSLFRQTHSLPYYIDK 880 
WD40-rpts                                                                                      

Query      881 HTHSLYHRRAAGIYSTRVARGKWQSLERRISDIIMQRMTISNMEADMNRLLKQREELTRRRDKISRKRERLLADDPEVEK 960 
WD40-rpts                                                                                      

Query      961 HLQPVNEELESLLANIDYINDSISDCQANIMQMEEAKEEGDAVDVSAVISSCTLAEARFLLDHFMSMALNKGLQAAQKES 1040
WD40-rpts                                                                                      

Query     1041 QIKVMEGRLKQTEINSATQNQLLFHMLKEKAEFNPELDALLGNALQELGNVPLENGDDSSSDESTPSPAVEGNTLASDLM 1120
WD40-rpts                                                                                      

Query     1121 KLCGETKSRTKARRRTTTQMELLYVDSGQDAATKDFTIPLHPMAETSEGSGELESAGNTVRDRDYMPSPAGLTSRMGGIW 1200
WD40-rpts                                                                                      

Query     1201 IRSSGCGQKRLPEPSPLSRRKTYDKGQAQADKAKSKEILQRREECLPLNPSIHLELGAFIFSSACIKQRDTTENKGMMAD 1280
WD40-rpts                                                                                      

Query     1281 SEVFWVNYSAIKKGIINPVPVWKSARGGGGGTLQCVHVAEGHSKAVLCVESTDDLMFTGSKDRTCKVWNLVTGQEIMSLG 1360
WD40-rpts                                            (_____________WD 1____________)      (____

Query     1361 GHPNNVVSVRYSSSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGLVNTGDMCAASTNRTVTIPAGENQINQIYLNPSGTVL 1440
WD40-rpts      __________WD 2_____________)                                                    

Query     1441 YAAAGNSVRVWDLRRFVCTGKLTGHLGPVMCLTVDQTGNGQDLVITGSKDHYIKMFDVTEGAMGSISPTHNFEPPHYDGI 1520
WD40-rpts                  (____________________WD 3___________________)(____________________WD

Query     1521 ESLVVQGDCLFSGSRDNGIKKWDLTRKDLLQQVPNAHRDWVCALGVVPASAILLSGCRAGVLKLWHTDTLSPLGEIRGHE 1600
WD40-rpts       4____________________)        (_______________WD 5______________)              

Query     1601 SPINSISTNSTHLFTAADDRTVKIWRARGSLDGSADVGDTMEEGVSN 1647
WD40-rpts

5 WD40-repeats found in QUERY=ENSDARP00000014740 (Len=1647):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 13  1319-1349     4.16  286.65  0.00851       30.0%     22.19
  WD 2:  Seg 15  1356-1388     3.15  244.60  0.03102       35.0%     37.10
  WD 3:  Seg 23  1453-1497     4.13  285.34  0.00886       30.0%     40.04
  WD 4:  Seg 26  1498-1543     4.11  284.43  0.00911       35.0%     24.94
  WD 5:  Seg 28  1552-1586     4.86  315.31  0.00350       22.5%     33.28

Multiple sequence alignment of 5 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1319-1349   ---------AEG--------HSKAVLCVESTDD-----LMFTGSKDRTCKVWN
   WD 2 1356-1388   ------IMSLGG--------HPNNVVSVRYSSS------LVFTVSTSYIKVWD
   WD 3 1453-1497   LRRFVCTGKLTG--------HLGPVMCLTVDQTGNGQDLVITGSKDHYIKMFD
   WD 4 1498-1543   VTE--GAMGSISPTHNFEPPHYDGIESLVVQ--GD---CLFSGSRDNGIKKWD
   WD 5 1552-1586   -------QVPNA--------HRDWVCALGVVPASA---ILLSGCRAGVLKLWH

   WD40 Template    TGE--CLRTLSG--------HTSGVTSVSFSPDGK---RLVSGSEDGTIKVWD