Accession: ENSDARP00000028109 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSDARP00000028109 (Len=445)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSDARP00000028109, Len=445):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MKVKVLCRNPDDYVRETTRDIQRVPRNYDPTLHPFEVPREYTRALNATKLERVFAKPFVASLDGHRDGISCISKHAKSLS 80  
WD40-rpts      (_______________________WD 1_______________________)   (_________________WD 2___

Query       81 TVISGACDGEVKVWNLPKRECTRTVQAHEGFVRGICSRFCGTSFFTVGDDKTIKQWNMEAPGYGVREEPINTILGKAVFT 160 
WD40-rpts      ______________)   (_________________WD 3________________)         (_____________

Query      161 GIDHHQREGTFVTCGQTVDIWDEQRSSPVLSFSWGVDSFSSVRYNPVETDLLASCASDRSIVLYDTRESAPLRKVIMQLR 240 
WD40-rpts      __WD 4_______________)   (_________________WD 5_________________)   (___________

Query      241 SNTLCWNPMEAYYFTCANEDYNLYTYDIRNLDVPVTVHMDHVSAVLDVDYSPTGREFVSASFDKTVRIFPKDKGHSREVY 320 
WD40-rpts      ______WD 6________________)(___________________WD 7__________________)   (______

Query      321 HTKRMQHVICVKWSADSKFIMSGSDEMNIRLWKANASEKLGVLSTREKTAANYNKKLIQKFQHHPQVRRIARHRHLPRDV 400 
WD40-rpts      ___________WD 8_________________)   (_______________WD 9______________)         

Query      401 LKQKRELKEMKEARRRKEQNVRKHSKPGSVPLLTEKEKHVVKVVE 445 
WD40-rpts

9 WD40-repeats found in QUERY=ENSDARP00000028109 (Len=445):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     1-52       2.91  234.78  0.04185        5.0%     36.46
  WD 2:  Seg  4    56-95       8.29  457.26  4.3e-05       30.0%     47.79
  WD 3:  Seg  8    99-137      9.20  494.69  1.3e-05       30.0%     57.54
  WD 4:  Seg 12   147-182      4.75  311.07  0.00399       20.0%     33.42
  WD 5:  Seg 15   186-225      7.34  417.90  0.00015       22.5%     56.34
  WD 6:  Seg 19   229-267      7.33  417.49  0.00015       15.0%     55.49
  WD 7:  Seg 23   268-310      8.76  476.32  2.4e-05       30.0%     53.15
  WD 8:  Seg 27   314-353      7.61  429.10  0.00010       27.5%     54.29
  WD 9:  Seg 31   357-391      2.98  237.82  0.03816       12.5%     38.92

Multiple sequence alignment of 9 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    1-52     MKV---KVLCR-NPDDYVRETTRDIQRVPRNYDPT-LHP-FEVPREYTRALNATKLER
   WD 2   56-95     -KP---FVASL-D------------GHRDGISCISKHAK-SLSTVISGACDGEVKVWN
   WD 3   99-137    -RE---CTRTV-Q------------AHEGFVRGIC-SRF-CGTSFFTVGDDKTIKQWN
   WD 4  147-182    -EE---PINTI-L------------GKAVFTGIDH-HQR-EGTFVTCGQ---TVDIWD
   WD 5  186-225    -SS---PVLSF-S------------WGVDSFSSVR-YNPVETDLLASCASDRSIVLYD
   WD 6  229-267    -SA---PLRKV-I------------MQLRSNTLCW-NPM-EAYYFTCANEDYNLYTYD
   WD 7  268-310    IRNLDVPVTVH-M------------DHVSAVLDVD-YSP-TGREFVSASFDKTVRIFP
   WD 8  314-353    -GH---SREVYHT------------KRMQHVICVK-WSA-DSKFIMSGSDEMNIRLWK
   WD 9  357-391    -SE---KLGVL-S------------TRE----KTA-ANY-NKKLIQKFQHHPQVRRIA

   WD40 Template    TGE---CLRTL-S------------GHTSGVTSVS-FSP-DGKRLVSGSEDGTIKVWD