Accession: ENSP00000025399 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000025399 (Len=363)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000025399, Len=363):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAMRQTPLTCSGHTRPVVDLAFSGITPYGYFLISACKGAGQHLPRLSGQHDGKPMLRQGDTGDWIGTFLGHKGAVWGATL 80  
WD40-rpts        (___________________WD 1__________________)                (_________________W

Query       81 NKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIK 160 
WD40-rpts      D 2________________)   (________________WD 3________________)(__________________

Query      161 KALWCSEDKQILSADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATIN 240 
WD40-rpts      WD 4__________________)   (________________WD 5_______________)   (_____________

Query      241 SASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWKCVL 320 
WD40-rpts      ___WD 6________________)   (_________________WD 7________________)              

Query      321 PEEDSGELAKPKIGFPETTEEELEEIASENSDCIFPSAPDVKA 363 
WD40-rpts

7 WD40-repeats found in QUERY=ENSP00000025399 (Len=363):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     3-45       7.66  431.08  9.6e-05       30.0%     36.03
  WD 2:  Seg  5    62-100      9.74  516.97  6.7e-06       30.0%     53.19
  WD 3:  Seg  9   104-141      8.40  461.66  3.7e-05       32.5%     55.96
  WD 4:  Seg 13   142-183      8.09  448.93  5.5e-05       30.0%     49.46
  WD 5:  Seg 17   187-223      5.43  339.08  0.00168       22.5%     52.34
  WD 6:  Seg 21   227-264      7.73  434.06  8.8e-05       22.5%     53.05
  WD 7:  Seg 25   268-306     10.68  556.03  2.0e-06       47.5%     53.74

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    3-45     MRQ---TPLTCSGHTRPVVDLAFSGITPYGYFLISACKGAGQHLPR
   WD 2   62-100    -GD---WIGTFLGHKGAVWGATLN---KDATKAATAAADFTAKVWD
   WD 3  104-141    -GD---ELMTL-AHKHIVKTVDFT---QDSNYLLTGGQDKLLRIYD
   WD 4  142-183    LNKPEAEPKEISGHTSGIKKALWC---SEDKQILSAD-DKTVRLWD
   WD 5  187-223    -MT---EVKSLNFNMS-VSSMEYI---PEGEILVITY-GRSIAFHS
   WD 6  227-264    -LD---PIKSFEAPAT-INSASLH---PEKEFLVAGGEDFKLYKYD
   WD 7  268-306    -GE---ELESYKGHFGPIHCVRFS---PDGELYASGSEDGTLRLWQ

   WD40 Template    TGE---CLRTLSGHTSGVTSVSFS---PDGKRLVSGSEDGTIKVWD