Accession: ENSP00000038176 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000038176 (Len=917)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000038176, Len=917):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAFIRKKQQEQQLQLYSKERFSLLLLNLEEYYFEQHRANHILHKGSHHERKIRGSLKICSKSVIFEPDSISQPIIKIPLR 80  
WD40-rpts                                                                                      

Query       81 DCIKIGKHGENGANRHFTKAKSGGISLIFSQVYFIKEHNVVAPYKIERGKMEYVFELDVPGKVEDVVETLLQLHRASCLD 160 
WD40-rpts                                                                                      

Query      161 KLGDQTAMITAILQSRLARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITLQDV 240 
WD40-rpts                                                                                      

Query      241 RRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHVAEHTAESYMLQWQRGHLSNYQYLLHLN 320 
WD40-rpts                                                                                      

Query      321 NLADRSCNDLSQYPVFPWIIHDYSSSELDLSNPGTFRDLSKPVGALNKERLERLLTRYQEMPEPKFMYGSHYSSPGYVLF 400 
WD40-rpts                                                                                      

Query      401 YLVRIAPEYMLCLQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYGDDVSFLVNSLKLDLGKRQGGQMVDDVELP 480 
WD40-rpts                                                                                      

Query      481 PWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVFHPLTYEGGVDLNSIQDPDEKVAMLTQILEF 560 
WD40-rpts                                                                                      

Query      561 GQTPKQLFVTPHPRRITPKFKSLSQTSSYNASMADSPGEESFEDLTEESKTLAWNNITKLQLHEHYKIHKEAVTGITVSR 640 
WD40-rpts                                                  (________________________WD 1_______

Query      641 NGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDATVITSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKI 720 
WD40-rpts      _________________)   (_________________WD 2________________)   (________________

Query      721 CWHDNRLYSASWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQ 800 
WD40-rpts      WD 3_______________)(_______________________WD 4______________________)   (_____

Query      801 IPCHSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTSDEPQRCFVWDGNSVLSGSQSGELLVWDLLGAKISE 880 
WD40-rpts      ____________WD 5________________)(_________________WD 6________________)   (____

Query      881 RIQGHTGAVTCIWMNEQCSSIITGGEDRQIIFWKLQY 917 
WD40-rpts      _____________WD 7________________)

7 WD40-repeats found in QUERY=ENSP00000038176 (Len=917):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 17   605-658      3.51  259.52  0.01964       30.0%     44.42
  WD 2:  Seg 20   662-700      4.09  283.68  0.00932       15.0%     52.25
  WD 3:  Seg 24   704-740      5.83  355.46  0.00101       37.5%     54.83
  WD 4:  Seg 28   741-791      5.22  330.30  0.00220       30.0%     52.29
  WD 5:  Seg 32   795-833      5.27  332.18  0.00208       27.5%     55.92
  WD 6:  Seg 36   834-872      4.00  279.71  0.01054       32.5%     37.31
  WD 7:  Seg 40   876-914      5.94  359.87  0.00088       25.0%     53.90

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  605-658    LTEE-----------SKTLAWNNITKLQLHEHYKIHKEAVTGITVSRNGSSVFTTSQDSTLKMFS
   WD 2  662-700    -KML-----------QRSI--------------SFSNMALSSCLLLPGDATVITSSWDNNVYFYS
   WD 3  704-740    -GRR-----------QDTL--------------MGHDDAVSKICWHDN--RLYSASWDSTVKVWS
   WD 4  741-791    GVPAEMPGTKRHHFDLLAE--------------LEHDVSVDTISLNAASTLLVSGTKEGTVNIWD
   WD 5  795-833    -ATL-----------MHQI--------------PCHSGIVCDTAFSPDSRHVLSTGTDGCLNVID
   WD 6  834-872    -VQT-----------GMLI--------------SSMTSDEPQRCFVWDGNSVLSGSQSGELLVWD
   WD 7  876-914    -AKI-----------SERI--------------QGHTGAVTCIWMNEQCSSIITGGEDRQIIFWK

   WD40 Template    TGEC-----------LRTL--------------SGHTSGVTSVSFSPDGKRLVSGSEDGTIKVWD