WDRR: WD40 Repeat Recognition
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| Pre-calculated Results - Accession: ENSP00000298315 [Homo sapiens] [Download result as txt] [Query sequence in FASTA]
Input parameters:
Query = ENSP00000298315 (Len=1969) Tmplt = WD40-str (Len=40) Method = bdp Gap-open = 50 Gap-extend = 3 Database = /home/pub/blastdb/nr90 E-value = 0.001 Iteration = 3Query sequence (ENSP00000298315, Len=1969): (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) 10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query 1 MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQ 80
WD40-rpts (__________________WD 1_______
Query 81 VGKEPYICIWDSYTVQTISVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDL 160
WD40-rpts __________) (__________________WD 2__________________) (_________________WD
Query 161 YQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHAAGI 240
WD40-rpts 3________________) (________________WD 4________________)(_______________
Query 241 FSMNACEEGFATGGRDGCIRLWDLTFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVQERNKPFLIM 320
WD40-rpts __WD 5________________) (______
Query 321 QGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNADGIHLALGMKDGSFTVLRVRDMTE 400
WD40-rpts ___________WD 6_________________) (_________________WD 7________________) (__
Query 401 VVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECLGSLSFITHLDWSSDSRYLQTNDGNGKRLFYRM 480
WD40-rpts _______________WD 8________________)(___________________WD 9__________________)
Query 481 PGGKEVTSTEEIKGVHWASWTCVSGLEVNGIWPKYSDINDINSVDGNYIGQVLVTADDYGIIKLFRYPCLRKGAKFRKYI 560
WD40-rpts (___________________WD10__________________) (_______
Query 561 GHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDAVHIAPQESLADSHSDESDSDLSDVPELDSEIEQETQLT 640
WD40-rpts __________WD11_________________)(______________WD12_____________)(______________
Query 641 YRRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQ 720
WD40-rpts ______WD13___________________) (___
Query 721 RFYLGHDDDILCLTIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGHHQYGVSAVDFSADGKRLASVGIDDSHTVVL 800
WD40-rpts _______________WD14_________________) (__________________WD15_________________
Query 801 WDWKKGEKLSIARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRKAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFS 880
WD40-rpts _) (_________________WD16________________) (________________WD17_____
Query 881 GTSTGDVCIWRDIFLVKTVKAHDGPVFSMHALEKGFVTGGKDGIVALWDDSFERCLKTYAIKRAALAPGSKGLLLEDNPS 960
WD40-rpts __________)(________________WD18________________) (_________________
Query 961 IRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLK 1040
WD40-rpts _WD19__________________) (_________________WD20________________) (__________
Query 1041 KGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDMISDIRFSPGSGKYLAVASHDSFIDIYNVMSSKRVGI 1120
WD40-rpts _______WD21________________) (_________________WD22_________________) (_____
Query 1121 CKGATSYITHIDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKIAWASWTSVLGLCCEGIWPVIGEVTDVTASC 1200
WD40-rpts ____________WD23________________) (________________
Query 1201 LTSDKMVLATGDDLGFVKLFRYPTKGKFGKFKRYVAHSTHVTNVRWTYDDSMLVTLGGTDMSLMVWTNEMEGYREKRPCD 1280
WD40-rpts WD24________________) (_________________WD25_________________) (__________
Query 1281 SEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGIKPHLQQKEPSIDERPPVSRAPPQPEKLQTNNVGKKKRPI 1360
WD40-rpts _______WD26________________) (_________________WD27________________)
Query 1361 EDLVLELIFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGSQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDS 1440
WD40-rpts (__________________WD28____
Query 1441 ADMSATAPSIHIWDAMNKQTLSILRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGAKIASRAGHNQRIFVAE 1520
WD40-rpts _____________) (__________________WD29__________________) (_________________
Query 1521 FRPDSDTQFVSVGVKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAIAFGANNLTFTGTISGDVCVWKDHILCRIVARA 1600
WD40-rpts WD30________________) (_________________WD31________________) (________
Query 1601 HNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQATDCVRSVCRGKGKILVGTRNAEIIEVGE 1680
WD40-rpts ____________WD32___________________)(___________________WD33___________________)
Query 1681 KNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFI 1760
WD40-rpts (_________________WD34_________________)(__________________WD35_______________
Query 1761 ILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSSYLQVS 1840
WD40-rpts __) (_________________WD36________________) (_______________WD37______
Query 1841 SGCYKRHVYEVPSGKHLMDHAAIDRITWATWTSILGDEVLGIWSRHAEKADVNCACVSHSGISLVTGDDFGMVKLFDFPC 1920
WD40-rpts _________) (___________________WD38___________________)
Query 1921 PEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCVHTPH 1969
WD40-rpts (_________________WD39_________________)
 39 WD40-repeats found in QUERY=ENSP00000298315 (Len=1969): (Red - Z-score>4.0) Rpts Segment Boundary Z-score Score P-value Identities SS-score WD 1: Seg 5 51-91 6.45 381.29 0.00045 20.0% 56.40 WD 2: Seg 9 95-136 6.36 377.39 0.00051 37.5% 56.28 WD 3: Seg 13 140-178 7.10 408.10 0.00020 22.5% 57.07 WD 4: Seg 17 187-224 4.71 309.42 0.00420 20.0% 44.78 WD 5: Seg 21 225-263 6.62 387.96 0.00037 30.0% 50.83 WD 6: Seg 29 314-353 6.98 402.91 0.00023 22.5% 57.74 WD 7: Seg 33 356-394 6.52 383.93 0.00042 20.0% 57.24 WD 8: Seg 37 398-436 7.69 432.46 9.2e-05 17.5% 58.82 WD 9: Seg 41 437-479 6.91 399.90 0.00025 17.5% 59.27 WD10: Seg 47 504-546 6.62 388.09 0.00037 22.5% 52.44 WD11: Seg 51 553-592 6.89 399.25 0.00026 32.5% 53.40 WD12: Seg 55 593-625 3.61 263.68 0.01728 12.5% 20.49 WD13: Seg 57 626-670 4.46 299.00 0.00580 12.5% 14.06 WD14: Seg 63 717-757 6.34 376.71 0.00052 22.5% 57.07 WD15: Seg 67 761-802 6.36 377.29 0.00051 47.5% 57.34 WD16: Seg 71 806-844 6.41 379.27 0.00048 20.0% 56.93 WD17: Seg 76 855-891 5.89 357.79 0.00094 12.5% 46.19 WD18: Seg 79 892-929 7.62 429.59 0.00010 27.5% 51.06 WD19: Seg 84 943-984 4.19 287.65 0.00825 15.0% 31.76 WD20: Seg 87 988-1026 6.50 383.32 0.00042 20.0% 55.46 WD21: Seg 91 1030-1068 7.57 427.36 0.00011 30.0% 58.53 WD22: Seg 95 1072-1111 6.44 380.56 0.00046 27.5% 58.25 WD23: Seg 99 1115-1153 6.63 388.39 0.00036 17.5% 57.26 WD24: Seg106 1184-1221 6.69 391.07 0.00033 22.5% 49.83 WD25: Seg110 1228-1267 6.17 369.56 0.00065 27.5% 48.18 WD26: Seg114 1270-1308 5.72 350.85 0.00116 15.0% 50.92 WD27: Seg118 1312-1350 6.19 370.40 0.00063 17.5% 43.08 WD28: Seg126 1414-1454 7.21 412.63 0.00017 20.0% 52.00 WD29: Seg130 1458-1499 6.10 366.54 0.00071 45.0% 57.39 WD30: Seg134 1503-1541 7.15 409.81 0.00019 20.0% 57.01 WD31: Seg139 1551-1589 6.67 390.04 0.00034 15.0% 43.45 WD32: Seg142 1592-1636 6.06 364.93 0.00075 22.5% 49.99 WD33: Seg146 1637-1680 5.69 349.54 0.00121 20.0% 51.60 WD34: Seg150 1683-1722 7.26 414.60 0.00016 30.0% 57.17 WD35: Seg154 1723-1763 5.78 353.39 0.00107 15.0% 55.77 WD36: Seg158 1767-1805 7.73 433.82 8.9e-05 20.0% 58.84 WD37: Seg163 1815-1850 6.06 365.06 0.00075 20.0% 43.53 WD38: Seg168 1874-1917 6.24 372.57 0.00059 22.5% 49.06 WD39: Seg172 1924-1963 6.33 376.11 0.00053 27.5% 51.50Multiple sequence alignment of 39 WD40-repeats: (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) WD 1 51-91 EH----R----------Q-KF-Y---RG--HSD-D-IISLALHP-ERVLVAT-GQVGKE------P--YICIWD WD 2 95-136 -V----Q----T-----I-SV-L---KD-VHTH-G-IACLAFDL-DGQRLVS-VG--LD----SKN--AVCVWD WD 3 140-178 -G----K----M-----L-SM-A---PG--HTD-R-IFDISWDL-YQPNKLV-SC--GV------K--HIKFWS WD 4 187-224 -K----R----G-----V-FG-K---TG--DLQ-T-ILCLACAR-DE-LTYS-GA--LN------G--DIYVWK WD 5 225-263 GI----N----L-----I-RTIQ---GA--HAA-G-IFSMNACE-EG--FAT-GG--RD------G--CIRLWD WD 6 314-353 -N----K----P-----F-LI-M---QG--HCE-GELWALAVHP-TKPLAVT-GS--DD------R--SVRIWS WD 7 356-394 -D----H----A-----L-IA-R---CN--MEE-P-IRCAAVNA-DGIHLAL-GM--KD------G--SFTVLR WD 8 398-436 -M----T----E-----V-VH-I---KD--RKE-A-IHELKYSP-DGTYLAV-GC--ND------S--SVDIYG WD 9 437-479 VA-QRYK----K-----V-GE-C---LG--SLS-F-ITHLDWSS-DSRYLQT-ND--GN------G--KRLFYR WD10 504-546 SG----L----E-----V-NG-IWPKYS--DIN-D-INSVDGNY-IGQVLVT-AD--DY------G--IIKLFR WD11 553-592 -G----A----K-----F-RK-Y---IG--HSA-H-VTNVRWSH-DYQWVISIGG--AD------H--SVFQWK WD12 593-625 ----------------------F---IP--ERK-L-KDAVHIAP-QESLADS-HS--DE------S--DSDLSD WD13 626-670 VP----E----LDSEIEQ-ET-Q---LT--YRR-Q-VYKEDLPQ-LKEQCKE-KQ--KS------A--TSKRRE WD14 717-757 QN----T----Q-------RF-Y---LG--HDD-D-ILCLTIHP-LKDYVAT-GQVGRD------P--SIHIWD WD15 761-802 -I----K----P-----L-SI-L---KG--HHQYG-VSAVDFSA-DGKRLAS-VG--ID------DSHTVVLWD WD16 806-844 -G----E----K-----L-SI-A---RG--SKD-K-IFVVKMNP-YVPDKLI-TA--GI------K--HMKFWR WD17 855-891 -----------G-----Y-IG-T---LG--KND-T-MMCAVYGW-TEEMAFS-GT--ST------G--DVCIWR WD18 892-929 DI----F----L-----V-KT-V---KA--HDG-P-VFSMHALE-KG--FVT-GG--KD------G--IVALWD WD19 943-984 RA----A----L-----A-PG-S---KGLLLED-N-PSIRAISL-GHGHILV-GT--KN------G--EILEVD WD20 988-1026 -P----I----T-----L-LV-Q---GH--MEG-E-VWGLATHP-YLPICAT-VS--DD------K--TLRIWD WD21 1030-1068 -S----H----C-----M-LA-V---RK--LKK-G-GRCCCFSP-DGKALAV-GL--ND------G--SFLMAN WD22 1072-1111 -L----E----D-----L-VS-F---HH--RKD-M-ISDIRFSPGSGKYLAV-AS--HD------S--FIDIYN WD23 1115-1153 -S----K----R-----V-GI-C---KG--ATS-Y-ITHIDWDI-RGKLLQV-NT--GA------K--EQLFFE WD24 1184-1221 EG---------------I-WP-V---IG--EVT-D-VTASCLTS-DKMVLAT-GD--DL------G--FVKLFR WD25 1228-1267 -F----G----K-----F-KR-Y---VA--HST-H-VTNVRWTY-DDSMLVTLGG--TD------M--SLMVWT WD26 1270-1308 -M----E----G-----Y-RE-K---RP--CDS-E-ESDIDSEE-DGGYDSD-VT--RE------N--EISYTI WD27 1312-1350 -S----T----N-----I-RP-M---LG--IKP-H-LQQKEPSI-DERPPVS-RA--PP------Q--PEKLQT WD28 1414-1454 ND----D----I-----LCLT-V---NQ--HPK-F-INIVATGQ-VGDSADM-SA--TA------P--SIHIWD WD29 1458-1499 -K----Q----T-----L-SI-L---RC-YHSK-G-VCSVSFSA-TGKLLLS-VG--LD----PEH--TITIWR WD30 1503-1541 -G----A----K-----I-AS-R---AG--HNQ-R-IFVAEFRP-DSDTQFV-SV--GV------K--HVKFWT WD31 1551-1589 KG----L----L-----S-TL-E---DA--RMQ-T-MLAIAFGA-NNLTF-T-GT--IS------G--DVCVWK WD32 1592-1636 -I----L----C-----R-IV-A---RA--HNG-P-VFAMYTTL-RDGLIVT-GG--KERPSKEGG--AVKLWD WD33 1637-1680 QELRRCR----A-----F-RL-E---TG--QAT-D-CVRSVCRG-KGKILVG-TR--NA------E--IIEVGE WD34 1683-1722 -A----A----C-----N-IL-V---NG--HVD-GPIWGLATHP-SRDFFLS-AA--ED------G--TVRLWD WD35 1723-1763 IA----D---KK-----M-LN-K---VN--LGH-A-ARTVCYSP-EGDMVAI-GM--KN------G--EFIILL WD36 1767-1805 -L----K----I-----W-GK-K---RD--RRC-A-IHDIRFSP-DSRYLAV-GS--SE------N--SVDFYD WD37 1815-1850 -----------------I-SY-C---KD--IPS-F-VIQMDFSA-DSSYLQV-SS--GC------Y--KRHVYE WD38 1874-1917 IL----GDEVLG-----I-WS-R---HA--EKA-D-VNCACVSH-SGISLVT-GD--DF------G--MVKLFD WD39 1924-1963 -F----A----K-----H-KR-F---LG--HSP-H-VTNIRFTS-GDRHVVSAGG--DD------C--SLFVWK WD40 Template TG----E----C-----L-RT-L---SG--HTS-G-VTSVSFSP-DGKRLVS-GS--ED------G--TIKVWD |
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