Accession: ENSP00000328494 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000328494 (Len=1624)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000328494, Len=1624):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYN 80  
WD40-rpts                                                                                      

Query       81 ATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFD 160 
WD40-rpts                                                                                      

Query      161 STRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240 
WD40-rpts                                                                                      

Query      241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHV 320 
WD40-rpts                                                                                      

Query      321 PYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELM 400 
WD40-rpts                                                                                      

Query      401 EYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN 480 
WD40-rpts                                                                                      

Query      481 YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRR 560 
WD40-rpts                                                                                      

Query      561 KSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLT 640 
WD40-rpts                                                                                      

Query      641 CEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRD 720 
WD40-rpts                                                                                      

Query      721 LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRA 800 
WD40-rpts                                                                                      

Query      801 LESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHF 880 
WD40-rpts                                                                                      

Query      881 LGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRK 960 
WD40-rpts                                                                                      

Query      961 RERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKA 1040
WD40-rpts                                                                                      

Query     1041 SIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQ 1120
WD40-rpts                                                                                      

Query     1121 SFTMKGSTSHDDFKFKSEPKLSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPT 1200
WD40-rpts                                                                                      

Query     1201 RGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKGIISPVGGAKGA 1280
WD40-rpts                                                                                      

Query     1281 RTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKV 1360
WD40-rpts                                    (_______________________WD 1______________________

Query     1361 WDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHI 1440
WD40-rpts      _)                                                       (______________________

Query     1441 GPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQ 1520
WD40-rpts      __WD 2________________________)                             (___________________

Query     1521 QELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWN 1600
WD40-rpts      ________WD 3___________________________)    (_______________WD 4_______________)

Query     1601 YVPGLTPCLPRRVLAIKGRATTLP 1624
WD40-rpts

4 WD40-repeats found in QUERY=ENSP00000328494 (Len=1624):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 14  1311-1362     3.25  249.08  0.02705       30.0%     41.44
  WD 2:  Seg 21  1418-1471     3.40  254.94  0.02260       27.5%     48.31
  WD 3:  Seg 26  1501-1560     3.75  269.57  0.01441       22.5%     38.05
  WD 4:  Seg 30  1565-1600     4.25  290.26  0.00761       22.5%     25.68

Multiple sequence alignment of 4 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1311-1362   GSKDRSCKMWNLVTG------QEIAALKGHPNNVVSI--------------------KYCSHSG---LVFSVS-TSYIKVWD
   WD 2 1418-1471   SGN--------AVRIWELSRFQPVGKLTGHIGPVMCL--------------------TVTQTASQHDLVVTGSKDHYVKMFE
   WD 3 1501-1560   GDI--------LFSG-----------SRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRP---MLLSACRAGVIKVWN
   WD 4 1565-1600   T----------PIGE-----------IKGHDSPINAI--------------------C--TNAK---HIFTASSDCRVKLWN

   WD40 Template    TGE--------CLRT-----------LSGHTSGVTSV--------------------SFSPDGK---RLVSGSEDGTIKVWD