WDRR: WD40 Repeat Recognition
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| Pre-calculated Results - Accession: ENSP00000348842 [Homo sapiens] [Download result as txt] [Query sequence in FASTA]
Input parameters:
Query = ENSP00000348842 (Len=1958) Tmplt = WD40-str (Len=40) Method = bdp Gap-open = 50 Gap-extend = 3 Database = /home/pub/blastdb/nr90 E-value = 0.001 Iteration = 3Query sequence (ENSP00000348842, Len=1958): (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) 10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query 1 MADRTAPRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLALHPDKTLVATGQ 80
WD40-rpts (__________________WD 1_______
Query 81 VGKEPYICIWDSYNVQTVSLLKDVHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDP 160
WD40-rpts __________) (__________________WD 2__________________) (_________________WD
Query 161 YQPNRVVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGI 240
WD40-rpts 3________________) (________________WD 4________________)(_______________
Query 241 FSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERDKPMLIL 320
WD40-rpts __WD 5________________) (__________________WD 6_________________) (______
Query 321 QGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVAFSPDGSQLALGMKDGSFIVLRVRDMTE 400
WD40-rpts ___________WD 7_________________)(__________________WD 8_________________) (__
Query 401 VVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKIGECSKSLSFITHIDWSLDSKYLQTNDGAGERLFYRM 480
WD40-rpts _______________WD 9________________)(___________________WD10__________________)
Query 481 PSGKPLTSKEEIKGIPWASWTCVKGPEVSGIWPKYTEVTDINSVDANYNSSVLVSGDDFGLVKLFKFPCLKRGAKFRKYV 560
WD40-rpts (_________________WD11________________) (_______
Query 561 GHSAHVTNVRWSHDFQWVLSTGGADHSVFQWRFIPEGVSNGMLETAPQEGGADSYSEESDSDLSDVPELDSDIEQEAQIN 640
WD40-rpts __________WD12_________________) (_________________WD13________
Query 641 YDRQVYKEDLPQLKQQSKEKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQHSQ 720
WD40-rpts ________) (___
Query 721 RLYLGHDDDILSLTIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLVSVGLDDFHSIVF 800
WD40-rpts _______________WD14_________________) (__________________WD15_________________
Query 801 WDWKKGEKIATTRGHKDKIFVVKCNPHHVDKLVTVGIKHIKFWQQAGGGFTSKRGTFGSVGKLETMMCVSYGRMEDLVFS 880
WD40-rpts _) (_________________WD16________________) (________________WD17_____
Query 881 GAATGDIFIWKDILLLKTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRSALSTSSKGLLLEDNPS 960
WD40-rpts __________)(________________WD18________________) (___________
Query 961 IRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSAQHRMLAVRKLK 1040
WD40-rpts ____WD19_______________) (_________________WD20________________) (__________
Query 1041 KGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSKDTGKYLAVASHDNFVDIYNVLTSKRVGI 1120
WD40-rpts _______WD21________________) (_________________WD22_________________) (_____
Query 1121 CKGASSYITHIDWDSRGKLLQVNSGAREQLFFEAPRGKRHIIRPSEIEKIEWDTWTCVLGPTCEGIWPAHSDITDVNAAS 1200
WD40-rpts ____________WD23________________) (_____________________WD24_
Query 1201 LTKDCSLLATGDDFGFVKLFSYPVKGQHARFKKYVGHSAHVTNVRWLHNDSVLLTVGGADTALMIWTREFVGTQESKLVD 1280
WD40-rpts ____________________) (_________________WD25_________________) (__________
Query 1281 SEESDTDVEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERPPVSRAAPQPEKLQKNNITKKKKLV 1360
WD40-rpts _______WD26________________) (__________________WD27__________________
Query 1361 EELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTT 1440
WD40-rpts ) (________________WD28_______________)(____________________WD29______________
Query 1441 PSIHIWDAMTKHTLSMLRCFHSKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDT 1520
WD40-rpts ______) (__________________WD30__________________) (_________________WD31___
Query 1521 QFVSVGVKHMKFWTLAGSALLYKKGVIGSLGAAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLIRLVAKAHTGPVFT 1600
WD40-rpts _____________) (________________WD32________________)(_________________
Query 1601 MYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGKILVGTKDGEIIEVGEKNAASNI 1680
WD40-rpts ____WD33____________________)(___________________WD34___________________) (____
Query 1681 LIDGHMEGEIWGLATHPSKDLFISASNDGTARIWDLADKKLLNKVSLGHAARCAAYSPDGEMVAIGMKNGEFVILLVNSL 1760
WD40-rpts _____________WD35_________________)(__________________WD36_________________) (
Query 1761 KVWGKKRDRKSAIQDIRISPDNRFLAVGSSEHTVDFYDLTQGTNLNRIGYCKDIPSFVIQMDFSADGKYIQVSTGAYKRQ 1840
WD40-rpts _________________WD37________________) (_______________WD38_____________
Query 1841 VHEVPLGKQVTEAVVIEKITWASWTSVLGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKH 1920
WD40-rpts __) (_____________________WD39____________________) (___
Query 1921 KRYFGHSAHVTNIRFSYDDKYVVSTGGDDCSVFVWRCL 1958
WD40-rpts ______________WD40_________________)
 40 WD40-repeats found in QUERY=ENSP00000348842 (Len=1958): (Red - Z-score>4.0) Rpts Segment Boundary Z-score Score P-value Identities SS-score WD 1: Seg 5 51-91 6.66 389.71 0.00035 22.5% 52.45 WD 2: Seg 9 95-136 6.44 380.80 0.00046 37.5% 57.06 WD 3: Seg 13 140-178 7.61 429.03 0.00010 25.0% 56.38 WD 4: Seg 17 187-224 4.96 319.61 0.00307 17.5% 49.71 WD 5: Seg 21 225-263 6.75 393.44 0.00031 30.0% 52.08 WD 6: Seg 25 270-310 3.48 258.61 0.02019 25.0% 40.05 WD 7: Seg 28 314-353 7.11 408.32 0.00020 25.0% 58.72 WD 8: Seg 32 354-394 7.47 423.17 0.00012 35.0% 58.06 WD 9: Seg 36 398-436 8.14 450.72 5.2e-05 27.5% 59.36 WD10: Seg 40 437-479 6.98 403.14 0.00023 20.0% 56.40 WD11: Seg 46 508-546 6.84 397.11 0.00028 20.0% 40.05 WD12: Seg 49 553-592 6.72 392.14 0.00032 32.5% 53.28 WD13: Seg 53 611-649 4.46 298.76 0.00585 10.0% 43.00 WD14: Seg 63 717-757 6.68 390.41 0.00034 27.5% 49.78 WD15: Seg 67 761-802 6.85 397.66 0.00027 47.5% 55.52 WD16: Seg 71 806-844 7.13 409.16 0.00019 25.0% 56.91 WD17: Seg 76 855-891 6.30 374.81 0.00055 20.0% 42.34 WD18: Seg 79 892-929 8.24 455.17 4.6e-05 27.5% 54.16 WD19: Seg 85 949-984 3.24 248.56 0.02749 12.5% 40.22 WD20: Seg 89 988-1026 6.78 394.66 0.00030 17.5% 55.67 WD21: Seg 93 1030-1068 7.67 431.44 9.5e-05 30.0% 58.43 WD22: Seg 97 1072-1111 6.67 390.04 0.00034 22.5% 58.00 WD23: Seg101 1115-1153 6.96 402.31 0.00024 17.5% 56.60 WD24: Seg107 1174-1221 6.52 384.08 0.00041 22.5% 43.95 WD25: Seg111 1228-1267 6.09 366.28 0.00072 25.0% 52.29 WD26: Seg115 1270-1308 4.07 282.93 0.00954 10.0% 40.88 WD27: Seg120 1320-1361 3.47 258.13 0.02050 10.0% 26.96 WD28: Seg123 1365-1401 3.01 239.19 0.03660 12.5% 48.79 WD29: Seg127 1402-1447 4.93 318.36 0.00319 25.0% 54.47 WD30: Seg131 1451-1492 6.13 367.77 0.00069 42.5% 57.69 WD31: Seg135 1496-1534 7.39 420.00 0.00014 22.5% 57.51 WD32: Seg140 1545-1582 5.78 353.60 0.00107 20.0% 42.99 WD33: Seg143 1583-1629 6.33 376.11 0.00053 25.0% 50.59 WD34: Seg147 1630-1673 5.95 360.53 0.00086 17.5% 46.29 WD35: Seg151 1676-1715 7.01 404.17 0.00022 27.5% 57.32 WD36: Seg155 1716-1756 6.31 375.12 0.00055 17.5% 55.87 WD37: Seg159 1760-1798 8.09 448.77 5.6e-05 22.5% 58.92 WD38: Seg164 1808-1843 6.41 379.32 0.00048 25.0% 47.05 WD39: Seg168 1864-1910 6.42 379.75 0.00047 20.0% 42.50 WD40: Seg172 1917-1956 6.80 395.58 0.00029 35.0% 48.89Multiple sequence alignment of 40 WD40-repeats: (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) WD 1 51-91 EH----S----------QK-------FF-L--G-HND-D-IISLAL-H--PD-KT-LVAT-G--QVGKE------P--Y---ICIWD WD 2 95-136 -V----Q-T--------VS-------LL-K--DVHTH-G-VACLAF-D--SD-GQ-RLAS-V--G--LD------AKNT---VCIWD WD 3 140-178 -G----K-L--------LA-------SA-T--G-HSD-R-IFDISW-D--PY-QP-NRVV-S--C--GV------K--H---IKFWT WD 4 187-224 -K----R-G--------IF-------GK-T--G-DLQ-T-ILCLAC-A--KE-D--ITYS-G--A--LN------G--D---IYVWK WD 5 225-263 GL----N-L--------VR-------TIQG--A-HSA-G-IFSMYA-C--EE-G---FAT-G--G--RD------G--C---IRLWD WD 6 270-310 TK----I-D--------LR------ETE-Q--G-YKGLS-IRSVCW-K--AD-R--LLAG-T--Q--DS------E--I---FEVIV WD 7 314-353 -D----K-P--------ML-------IL-Q--G-HCE-GELWALAL-H--PK-KP-LAVT-G--S--DD------R--S---VRLWS WD 8 354-394 LA----DHA--------LI-------AR-C--N-MEE-A-VRSVAF-S--PD-GS-QLAL-G--M--KD------G--S---FIVLR WD 9 398-436 -M----T-E--------VV-------HI-K--D-RKE-V-IHEMKF-S--PD-GS-YLAV-G--S--ND------G--P---VDVYA WD10 437-479 VA-QRYK-K--------IG-------EC-S--K-SLS-F-ITHIDW-S--LD-SK-YLQT-N--D--GA------G--E---RLFYR WD11 508-546 -V----S-G--------IW-------PK-Y--T-EVT-D-INSVDA-N--YN-SS-VLVS-G--D--DF------G--L---VKLFK WD12 553-592 -G----A-K--------FR-------KY-V--G-HSA-H-VTNVRW-S--HD-FQWVLST-G--G--AD------H--S---VFQWR WD13 611-649 -G----A-D--------SY-------SE-E--S-DSD-L-SDVPEL-D--SD-IE-QEAQ-I--N--YD------R--Q---VYKED WD14 717-757 -Q----H-S--------QR-------LY-L--G-HDD-D-ILSLTI-H--PV-KD-YVAT-GQVG--RD------A--A---IHVWD WD15 761-802 -L----K-C--------LS-------LL-K--GQHQR-G-VCALDF-S--AD-GK-CLVS-V--G--LD------DFHS---IVFWD WD16 806-844 -G----E-K--------IA-------TT-R--G-HKD-K-IFVVKC-N--PH-HV-DKLV-T--V--GI------K--H---IKFWQ WD17 855-891 --------G--------TF-------GS-V--G-KLE-T-MMCVSY-G--RM-ED-LVFS-G--A--AT------G--D---IFIWK WD18 892-929 DI----L-L--------LK-------TV-K--A-HDG-P-VFAMYA-L--DK-G---FVT-G--G--KD------G--I---VELWD WD19 949-984 SS----K-G--------LL-------L--------ED-N-PSIRAI-T--LG-HG-HILV-G--T--KN------G--E---ILEID WD20 988-1026 -P----M-T--------LL-------VQ-G--H-MEG-E-VWGLAA-H--PL-LP-ICAT-V--S--DD------K--T---LRIWE WD21 1030-1068 -Q----H-R--------ML-------AV-R--K-LKK-G-GRCCAF-S--PD-GK-ALAV-G--L--ND------G--S---FLVVN WD22 1072-1111 -V----E-D--------MV-------SF-H--H-RKE-M-ISDIKF-S--KDTGK-YLAV-A--S--HD------N--F---VDIYN WD23 1115-1153 -S----K-R--------VG-------IC-K--G-ASS-Y-ITHIDW-D--SR-GK-LLQV-N--S--GA------R--E---QLFFE WD24 1174-1221 TW----T-CVLGPTCEGIW-------PA-H--S-DIT-D-VNAASL-T--KD-CS-LLAT-G--D--DF------G--F---VKLFS WD25 1228-1267 -H----A-R--------FK-------KY-V--G-HSA-H-VTNVRWLH--ND-SV-LLTV-G--G--AD------T--A---LMIWT WD26 1270-1308 -F----V-G--------TQ-------ES-K--L-VDS-E-ESDTDV-E--ED-GG-YDSD-V--A--RE------K--A---IDYTT WD27 1320-1361 GT----K-P--------HQ-------QL-KEVS-VEE-R-PPVSRA-A--PQ-PE-KLQK-N--N--IT------K--K---KKLVE WD28 1365-1401 -L----D-H--------VF-------GY-R--G-FDC---RNNLHY-L--ND-GA-DIIF-H--T--AA------A--G---I-VQN WD29 1402-1447 LS----TGS--------QS-------FY-L--E-HTD-D-ILCLTV-NQHPK-YR-NVVA-T--S--QI------G--TTPSIHIWD WD30 1451-1492 -K----H-T--------LS-------ML-R--CFHSK-G-VNYINF-S--AT-GK-LLVS-V--G--VD----PEH--T---ITVWR WD31 1496-1534 -G----A-K--------VA-------SR-G--G-HLE-R-IFVVEF-R--PD-SD-TQFV-S--V--GV------K--H---MKFWT WD32 1545-1582 -G----V-I--------GS-------LG-A--A-KMQ-T-MLSVAF-G--AN-N--LTFT-G--A--IN------G--D---VYVWK WD33 1583-1629 DH----F-L--------IR------LVA-K--A-HTG-P-VFTMYT-T--LR-DG-LIVT-G--G--KERPTKEGG--A---VKLWD WD34 1630-1673 QEMKRCR-A--------FQ-------LE-T--G-QLV-E-CVRSVC-R--GK-GK-ILVG-T--K--DG------E--I---IEVGE WD35 1676-1715 -A----A-S--------NI-------LI-D--G-HME-GEIWGLAT-H--PS-KD-LFIS-A--S--ND------G--T---ARIWD WD36 1716-1756 LA----DKK--------LL-------NK-V--S-LGH-A-ARCAAY-S--PD-GE-MVAI-G--M--KN------G--E---FVILL WD37 1760-1798 -L----K-V--------WG-------KK-R--D-RKS-A-IQDIRI-S--PD-NR-FLAV-G--S--SE------H--T---VDFYD WD38 1808-1843 IG----Y-C--------------------K--D-IPS-F-VIQMDF-S--AD-GK-YIQV-S--T--GA------Y--K---RQVHE WD39 1864-1910 WT----S-V--------LGDEVIGIWPR-N--A-DKA-D-VNCACV-T--HA-GL-NIVT-G--D--DF------G--L---VKLFD WD40 1917-1956 -F----A-K--------HK-------RY-F--G-HSA-H-VTNIRF-S--YD-DK-YVVSTG--G--DD------C--S---VFVWR WD40 Template TG----E-C--------LR-------TL-S--G-HTS-G-VTSVSF-S--PD-GK-RLVS-G--S--ED------G--T---IKVWD |
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