Accession: ENSP00000351811 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000351811 (Len=1401)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000351811, Len=1401):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVI 80  
WD40-rpts                                                                                      

Query       81 CLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVR 160 
WD40-rpts                                                                                      

Query      161 VISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPF 240 
WD40-rpts         (__________________WD 1__________________)                                   

Query      241 IPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGY 320 
WD40-rpts                                                    (_________________WD 2____________

Query      321 VKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDI 400 
WD40-rpts      ____)        (_______________________WD 3______________________)   (____________

Query      401 FSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPA 480 
WD40-rpts      ____WD 4________________)                                                       

Query      481 EEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGS 560 
WD40-rpts                                                                                      

Query      561 AAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTS 640 
WD40-rpts                                                                                      

Query      641 AVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLP 720 
WD40-rpts                                                                                      

Query      721 QASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPG 800 
WD40-rpts                                                                                      

Query      801 DGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSD 880 
WD40-rpts                                                                                      

Query      881 HDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRE 960 
WD40-rpts                                                                                      

Query      961 LAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLE 1040
WD40-rpts                                                                                      

Query     1041 RSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQS 1120
WD40-rpts                                                                                      

Query     1121 VVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEV 1200
WD40-rpts                                                                                      

Query     1201 QHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQA 1280
WD40-rpts                                                                                      

Query     1281 FQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGS 1360
WD40-rpts                                                                                      

Query     1361 VMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP 1401
WD40-rpts

4 WD40-repeats found in QUERY=ENSP00000351811 (Len=1401):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  9   164-205      5.85  356.48  0.00098       30.0%     48.55
  WD 2:  Seg 17   287-325      7.65  430.50  9.8e-05       30.0%     52.30
  WD 3:  Seg 21   334-384      3.27  249.66  0.02658       17.5%     40.98
  WD 4:  Seg 25   388-425      4.01  280.24  0.01037       25.0%     31.82

Multiple sequence alignment of 4 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  164-205    VSTSERTLLKGFTG-SVADLAFAHLNSPQ-----------LACLDEAGNLFVWR
   WD 2  287-325    -KQGFIV-VKGHST-CLSEGALS-PDGTV-----------LATASHDGYVKFWQ
   WD 3  334-384    -PRCLHE-WKPHDGRPLSCLLFC-DNHKKQDPDVPFWRFLITGADQNRELKMWC
   WD 4  388-425    -WTCLQT-IRFSPD-IFSSVSVP-PSLKV-----------CLDLS-AEYLILSD

   WD40 Template    TGECLRT-LSGHTS-GVTSVSFS-PDGKR-----------LVSGSEDGTIKVWD