WDRR: WD40 Repeat Recognition
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| Pre-calculated Results - Accession: ENSP00000352180 [Homo sapiens] [Download result as txt] [Query sequence in FASTA]
Input parameters:
Query = ENSP00000352180 (Len=2619) Tmplt = WD40-str (Len=40) Method = bdp Gap-open = 50 Gap-extend = 3 Database = /home/pub/blastdb/nr90 E-value = 0.001 Iteration = 3Query sequence (ENSP00000352180, Len=2619): (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) 10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query 1 MEKLHGHVSAHPDILSLENRCLAMLPDLQPLEKLHQHVSTHSDILSLKNQCLATLPDLKTMEKPHGYVSAHPDILSLENQ 80
WD40-rpts
Query 81 CLATLSDLKTMEKPHGHVSAHPDILSLENRCLATLSSLKSTVSASPLFQSLQISHMTQADLYRVNNSNCLLSEPPSWRAQ 160
WD40-rpts
Query 161 HFSKGLDLSTCPIALKSISATETAQEATLGRWFDSEEKKGAETQMPSYSLSLGEEEEVEDLAVKLTSGDSESHPEPTDHV 240
WD40-rpts
Query 241 LQEKKMALLSLLCSTLVSEVNMNNTSDPTLAAIFEICRELALLEPEFILKASLYARQQLNVRNVANNILAIAAFLPACRP 320
WD40-rpts
Query 321 HLRRYFCAIVQLPSDWIQVAELYQSLAEGDKNKLVPLPACLRTAMTDKFAQFDEYQLAKYNPRKHRAKRHPRRPPRSPGM 400
WD40-rpts
Query 401 EPPFSHRCFPRYIGFLREEQRKFEKAGDTVSEKKNPPRFTLKKLVQRLHIHKPAQHVQALLGYRYPSNLQLFSRSRLPGP 480
WD40-rpts
Query 481 WDSSRAGKRMKLSRPETWERELSLRGNKASVWEELIENGKLPFMAMLRNLCNLLRVGISSRHHELILQRLQHAKSVIHSR 560
WD40-rpts
Query 561 QFPFRFLNAHDAIDALEAQLRNQALPFPSNITLMRRILTRNEKNRPRRRFLCHLSRQQLRMAMRIPVLYEQLKREKLRVH 640
WD40-rpts
Query 641 KARQWKYDGEMLNRYRQALETAVNLSVKHSLPLLPGRTVLVYLTDANADRLCPKSNPQGPPLNYALLLIGMMITRAEQVD 720
WD40-rpts
Query 721 VVLCGGDTLKTAVLKAEEGILKTAIKLQAQVQEFDENDGWSLNTFGKYLLSLAGQRVPVDRVILLGQSMDDGMINVAKQL 800
WD40-rpts
Query 801 YWQRVNSKCLFVGILLRRVQYLSTDLNPNDVTLSGCTDAILKFIAEHGASHLLEHVGQMDKIFKIPPPPGKTGVQSLRPL 880
WD40-rpts
Query 881 EEDTPSPLAPVSQQGWRSIRLFISSTFRDMHGERDLLLRSVLPALQARAAPHRISLHGIDLRWGVTEEETRRNRQLEVCL 960
WD40-rpts
Query 961 GEVENAQLFVGILGSRYGYIPPSYNLPDHPHFHWAQQYPSGRSVTEMEVMQFLNRNQRLQPSAQALIYFRDSSFLSSVPD 1040
WD40-rpts
Query 1041 AWKSDFVSESEEAARRISELKSYLSRQKGITCRRYPCEWGGVAAGRPYVGGLEEFGQLVLQDVWNMIQKLYLQPGALLEQ 1120
WD40-rpts
Query 1121 PVSIPDDDLVQATFQQLQKPPSPARPRLLQDTVQRLMLPHGRLSLVTGQSGQGKTAFLASLVSALQAPDGAKVASLVFFH 1200
WD40-rpts
Query 1201 FSGARPDQGLALTLLRRLCTYLRGQLKEPGALPSTYRSLVWELQQRLLPKSAESLHPGQTQVLIIDGADRLVDQNGQLIS 1280
WD40-rpts
Query 1281 DWIPKKLPRCVHLVLSVSSDAGLGETLEQSQGAHVLALGPLEASARARLVREELALYGKRLEESPFNNQMRLLLVKRESG 1360
WD40-rpts
Query 1361 RPLYLRLVTDHLRLFTLYEQVSERLRTLPATVPLLLQHILSTLEKEHGPDVLPQALTALEVTRSGLTVDQLHGVLSVWRT 1440
WD40-rpts
Query 1441 LPKGTKSWEEAVAAGNSGDPYPMGPFACLVQSLRSLLGEGPLERPGARLCLPDGPLRTAAKRCYGKRPGLEDTAHILIAA 1520
WD40-rpts
Query 1521 QLWKTCDADASGTFRSCPPEALGDLPYHLLQSGNRGLLSKFLTNLHVVAAHLELGLVSRLLEAHALYASSVPKEEQKLPE 1600
WD40-rpts
Query 1601 ADVAVFRTFLRQQASILSQYPRLLPQQAANQPLDSPLCHQASLLSRRWHLQHTLRWLNKPRTMKNQQSSSLSLAVSSSPT 1680
WD40-rpts (______________
Query 1681 AVAFSTNGQRAAVGTANGTVYLLDLRTWQEEKSVVSGCDGISACLFLSDDTLFLTAFDGLLELWDLQHGCRVLQTKAHQY 1760
WD40-rpts ___WD 1________________) (________________WD 2________________) (___________
Query 1761 QITGCCLSPDCRLLATVCLGGCLKLWDTVRGQLAFQHTYPKSLNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGA 1840
WD40-rpts ______WD 3________________)(__________________WD 4_________________) (________
Query 1841 PGASIRTLAFNVPGGVVAVGRLDSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLLTAGEDGKVQVWSGSLGRPRG 1920
WD40-rpts _________WD 5________________) (_________________WD 6________________) (____
Query 1921 HLGSLSLSPALSVALSPDGDRVAVGYRADGIRIYKISSGSQGAQGQALDVAVSALAWLSPKVLVSGAEDGSLQGWALKEC 2000
WD40-rpts _____________WD 7_________________) (________________WD 8________________)(___
Query 2001 SLQSLWLLSRFQKPVLGLATSQELLASASEDFTVQLWPRQLLTRPHKAEDFPCGTELRGHEGPVSCCSFSTDGGSLATGG 2080
WD40-rpts _______________WD 9__________________) (_________________WD10________
Query 2081 RDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEH 2160
WD40-rpts ________)(____________________WD11___________________) (________________WD12__
Query 2161 VVSVSRDGTLKVWDHQGVELTSIPAHSGPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGP 2240
WD40-rpts _____________) (_____________________WD13_____________________) (____________
Query 2241 VRAAAVSETSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVSGNQAGELILWQEAKAVATAQAPG 2320
WD40-rpts _____WD14________________) (_________________WD15________________)(___________
Query 2321 HIGALIWSSAHTFFVLSADEKISEWQVKLRKGSAPGNLSLHLNRILQEDLGVLTSLDWAPDGHFLILAKADLKLLCMKPG 2400
WD40-rpts _____WD16________________) (_________________WD17________________)
Query 2401 DAPSEIWSSYTENPMILSTHKEYGIFVLQPKDPGVLSFLRQKESGEFEERLNFDINLENPSRTLISITQAKPESALMGSY 2480
WD40-rpts (__________________WD18__________________)(_________________WD19_________
Query 2481 GTWPNAAQKENGPQVTCGRKKNTPETQTPGTDPSTCRESDASMDSDASMDSEPTPHLKTRQRRKIHSGSVTALHVLPELL 2560
WD40-rpts ________) (_________________WD20________________) (________________WD21___
Query 2561 VTASKDRDVKLWERPSMQLLGLFRCEGSVSCLEPWLGANSTLQLAVGDVQGNVYFLNWE 2619
WD40-rpts ____________)
 21 WD40-repeats found in QUERY=ENSP00000352180 (Len=2619): (Red - Z-score>4.0) Rpts Segment Boundary Z-score Score P-value Identities SS-score WD 1: Seg 19 1666-1704 5.05 323.06 0.00275 27.5% 46.64 WD 2: Seg 22 1708-1745 5.19 329.14 0.00228 17.5% 54.82 WD 3: Seg 26 1749-1787 7.81 437.21 8.0e-05 27.5% 58.93 WD 4: Seg 30 1788-1828 7.14 409.76 0.00019 25.0% 57.61 WD 5: Seg 34 1832-1870 7.54 426.04 0.00011 15.0% 56.31 WD 6: Seg 38 1874-1912 8.37 460.60 3.9e-05 30.0% 54.03 WD 7: Seg 42 1916-1955 6.16 369.12 0.00066 30.0% 57.53 WD 8: Seg 46 1959-1996 5.90 358.42 0.00092 27.5% 52.52 WD 9: Seg 50 1997-2038 6.13 367.97 0.00068 22.5% 50.25 WD10: Seg 54 2051-2089 8.40 461.57 3.7e-05 37.5% 47.61 WD11: Seg 57 2090-2134 5.93 359.48 0.00089 27.5% 45.98 WD12: Seg 61 2138-2174 7.77 435.48 8.4e-05 42.5% 52.87 WD13: Seg 65 2177-2224 5.70 350.20 0.00119 17.5% 57.14 WD14: Seg 69 2228-2266 8.23 454.69 4.6e-05 27.5% 57.62 WD15: Seg 73 2270-2308 7.26 414.56 0.00016 27.5% 55.01 WD16: Seg 77 2309-2346 2.95 236.42 0.03982 15.0% 44.39 WD17: Seg 81 2360-2398 4.44 298.11 0.00597 22.5% 42.16 WD18: Seg 85 2408-2449 3.44 256.72 0.02140 17.5% 49.73 WD19: Seg 89 2450-2489 4.44 298.05 0.00598 7.5% 47.75 WD20: Seg 93 2493-2531 5.28 332.90 0.00203 12.5% 51.22 WD21: Seg 97 2537-2573 5.85 356.35 0.00098 25.0% 47.95Multiple sequence alignment of 21 WD40-repeats: (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) WD 1 1666-1704 -Q--Q------S--SSLSLAVS-SSPTAVAFSTNGQ---------RAAVGTANGTVYLLD WD 2 1708-1745 -W--Q------E--EKSVVSGC-DGISACLFLSDDT---------LFLT-AFDGLLELWD WD 3 1749-1787 -G--C------R--VLQTKAHQ-YQITGCCLSPDCR---------LLATVCLGGCLKLWD WD 4 1788-1828 TV--R-----GQ--LAFQHTYP-KSLNCVAFHPEGQ---------VIATGSWAGSISFFQ WD 5 1832-1870 -L--K------V--TKDLGAPG-ASIRTLAFNVPGG---------VVAVGRLDSMVELWA WD 6 1874-1912 -G--A------R--LAAFPAHH-GFVAAALFLHAGC---------QLLTAGEDGKVQVWS WD 7 1916-1955 -G--R------P--RGHLGSLSLSPALSVALSPDGD---------RVAVGYRADGIRIYK WD 8 1959-1996 -G--S------Q--GAQGQALD-VAVSALAWL-SPK---------VLVSGAEDGSLQGWA WD 9 1997-2038 LK--E------CSLQSLWLLSR-FQKPVLGLATSQE---------LLASASEDFTVQLWP WD10 2051-2089 -F--P------C--GTELRGHE-GPVSCCSFSTDGG---------SLATGGRDRSLLCWD WD11 2090-2134 VR--TPKTPVLI--HSFPACHR-DWVTGCAWTKDN----------LLISCSSDGSVGLWD WD12 2138-2174 -G--Q------R--LGQFLGHQ-SAVSAVAAVEEH-----------VVSVSRDGTLKVWD WD13 2177-2224 -G--V------E--LTSIPAHS-GPISHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWH WD14 2228-2266 -V--C------Q--THTLLGHS-GPVRAAAVSETSG---------LMLTASEDGSVRLWQ WD15 2270-2308 -E--A------D--DTCIPRSS-AAVTAVAWAPDGS---------MAVSGNQAGELILWQ WD16 2309-2346 EA--K------A--VATAQA-P-GHIGALIWSSAHT----------FFVLSADEKISEWQ WD17 2360-2398 -L--H------L--NRILQEDL-GVLTSLDWAPDGH---------FLILAKADLKLLCMK WD18 2408-2449 SSYTE------N--PMILSTHK-EYGIFVLQPKDPG---------VLSFLRQKESGEFEE WD19 2450-2489 RL--N------F--DINLENPS-RTLISITQAKPES---------ALMGSYGTWPNAAQK WD20 2493-2531 -P--Q------V--TCGRKKNT-PETQTPGTDPSTC---------RESDASMDSDASMDS WD21 2537-2573 -L--K------T--RQRRKIHS-GSVTALHVLPE-----------LLVTASKDRDVKLWE WD40 Template TG--E------C--LRTLSGHT-SGVTSVSFSPDGK---------RLVSGSEDGTIKVWD |
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