Accession: ENSP00000354851 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000354851 (Len=1661)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000354851, Len=1661):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGY 80  
WD40-rpts                                                                                      

Query       81 NATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLF 160 
WD40-rpts                                                                                      

Query      161 DTTRDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240 
WD40-rpts                                                                                      

Query      241 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATH 320 
WD40-rpts                                                                                      

Query      321 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMEL 400 
WD40-rpts                                                                                      

Query      401 MEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 480 
WD40-rpts                                                                                      

Query      481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVA 560 
WD40-rpts                                                                                      

Query      561 GKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCE 640 
WD40-rpts                                                                                      

Query      641 IAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 720 
WD40-rpts                                                                                      

Query      721 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLE 800 
WD40-rpts                                                                                      

Query      801 AQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALP 880 
WD40-rpts                                                                                      

Query      881 TPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 960 
WD40-rpts                                                                                      

Query      961 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGL 1040
WD40-rpts                                                                                      

Query     1041 QAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEG 1120
WD40-rpts                                                                                      

Query     1121 STLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1200
WD40-rpts                                                                                      

Query     1201 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVS 1280
WD40-rpts                                                                                      

Query     1281 QGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWN 1360
WD40-rpts                             (__________________________WD 1_________________________)

Query     1361 LVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1440
WD40-rpts              (______________WD 2_____________)                                       

Query     1441 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVS 1520
WD40-rpts                      (________________________WD 3________________________)(_________

Query     1521 PTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNM 1600
WD40-rpts      ___________WD 4____________________)       (_______________WD 5_______________) 

Query     1601 DTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1661
WD40-rpts        (________________WD 6_______________)

6 WD40-repeats found in QUERY=ENSP00000354851 (Len=1661):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 13  1304-1360     5.01  321.47  0.00289       37.5%     27.75
  WD 2:  Seg 16  1369-1401     4.40  296.59  0.00625       30.0%     37.53
  WD 3:  Seg 21  1457-1510     3.96  278.03  0.01110       32.5%     44.25
  WD 4:  Seg 25  1511-1556     4.28  291.53  0.00731       32.5%     24.06
  WD 5:  Seg 27  1564-1599     5.12  326.21  0.00250       27.5%     33.50
  WD 6:  Seg 29  1603-1639     2.96  236.86  0.03928       15.0%     30.35

Multiple sequence alignment of 6 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1304-1360   SSRRGIINPFPASKGIRAFPLQCIHI-----------AEG--------HTKAVLCVD---STDD--LLFTGSKDRTCKVWN
   WD 2 1369-1401   -------------------------S-----------LGG--------HPNNVVSVK---YCNYTSLVFTVS-TSYIKVWD
   WD 3 1457-1510   SG-------------------NAVRMWDLKRFQSTGKLTG--------HLGPVMCLTVDQISSGQDLIITGSKDHYIKMFD
   WD 4 1511-1556   VT-------------------EGALG-----------TVSPTHNFEPPHYDGIEALT---IQ--GDNLFSGSRDNGIKKWD
   WD 5 1564-1599   -----------------------QQV-----------PNA--------HKDWVCALG---VVPDHPVLLSGCRGGILKVWN
   WD 6 1603-1639   -F-------------------MPVGE-----------MKG--------HDSPINAIC---V--NSTHIFTAADDRTVRIWK

   WD40 Template    TG-------------------ECLRT-----------LSG--------HTSGVTSVS---FSPDGKRLVSGSEDGTIKVWD