Accession: ENSP00000360914 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSP00000360914 (Len=806)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSP00000360914, Len=806):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 XTDLSNIPGLLAIDQVLPEESQKAESQNTFEETELELKKCFPSDETCEKPVDETTKLTQTSSTEQLNVLETETEVLNKEA 80  
WD40-rpts                                                                                      

Query       81 VEVKGGGDVLEPVSSDSLSTKDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPTNFPPPRPPPPSRPAPPPRKR 160 
WD40-rpts                                                                                      

Query      161 KSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDSQPSLDLASATSGDKIVTAQENGKAPDGQTVAGEVMGPQRP 240 
WD40-rpts                                                                                      

Query      241 RSNSGRELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGINPLTLHIMRRTKEYVSNDAAQSDDEEKLQSQPTDTDGGR 320 
WD40-rpts                                                  (________________WD 1_______________

Query      321 LKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQI 400 
WD40-rpts      )                                  (__________________WD 2_________________)   (

Query      401 KVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGV 480 
WD40-rpts      _________________WD 3_________________)     (________________WD 4_______________

Query      481 CSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDD 560 
WD40-rpts      _)              (________________WD 5________________)(__________________WD 6___

Query      561 RYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNK 640 
WD40-rpts      _______________)(___________________WD 7___________________)               (____

Query      641 VGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLS 720 
WD40-rpts      ___________WD 8______________)   (__________________WD 9_________________)      

Query      721 KFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEVLDATPSAMSSRYVAQAGLELLASK 800 
WD40-rpts               (_________________WD10________________)                                

Query      801 RYYEDR 806 
WD40-rpts

10 WD40-repeats found in QUERY=ENSP00000360914 (Len=806):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  4   285-321      3.95  277.69  0.01122        7.5%      5.64
  WD 2:  Seg  9   356-396      4.83  314.04  0.00364        7.5%     13.03
  WD 3:  Seg 11   400-439      7.96  443.64  6.5e-05       30.0%     55.15
  WD 4:  Seg 15   445-482      6.30  375.03  0.00055       20.0%     29.84
  WD 5:  Seg 17   497-534      6.27  373.69  0.00057       27.5%     50.32
  WD 6:  Seg 21   535-576      7.15  410.13  0.00018       30.0%     55.51
  WD 7:  Seg 25   577-620      7.90  441.11  7.1e-05       27.5%     54.40
  WD 8:  Seg 30   636-670      6.20  370.84  0.00063       17.5%     49.27
  WD 9:  Seg 33   674-714      7.48  423.59  0.00012       32.5%     55.67
  WD10:  Seg 37   730-768      7.41  420.79  0.00013       17.5%     48.79

Multiple sequence alignment of 10 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  285-321    --------------TLHIMRR-TKEYVSND--AAQS-DDEEKLQSQPTDTDGGRL
   WD 2  356-396    SVRD----E--VFH----TDQ-DDPSSSDD--EGMP-YTRPVKFKAAHGFKGPYD
   WD 3  400-439    -I-K----V--VQD----LSGEHMGAVWTM--KFSH-CGRLLASAGQDNVVRIWA
   WD 4  445-482    ---------DYFNN----MRM-KYNTEGRV--SPSP-SQESLSSSKSDTDTGVCS
   WD 5  497-534    -Q-R----P--FCK----YKG-HTADLLDL--SWSK-NY-FLLSSSMDKTVRLWH
   WD 6  535-576    IS-R---RE--CLC----CFQ-HIDFVTAI--AFHPRDDRYFLSGSLDGKLRLWN
   WD 7  577-620    IP-DKKVAL--WNE----VDG-QTKLITAA--NFCQ-NGKYAVIGTYDGRCIFYD
   WD 8  636-670    RG-R---------------NK-VGRKITGI--EPLP-GENKILVTSNDSRIRLYD
   WD 9  674-714    -L-S----L--SMK----YKG-YVNSSSQIKASFSH-DFTYLVSGSEDKYVYIWS
   WD10  730-768    -N-D----F--WEG----IKA-HNAVVTSA--IFAP-NPSLMLSLDVQSEKSEGN

   WD40 Template    TG-E----C--LRT----LSG-HTSGVTSV--SFSP-DGKRLVSGSEDGTIKVWD