WDRR: WD40 Repeat Recognition
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| Pre-calculated Results - Accession: ENSP00000370039 [Homo sapiens] [Download result as txt] [Query sequence in FASTA]
Input parameters:
Query = ENSP00000370039 (Len=1977) Tmplt = WD40-str (Len=40) Method = bdp Gap-open = 50 Gap-extend = 3 Database = /home/pub/blastdb/nr90 E-value = 0.001 Iteration = 3Query sequence (ENSP00000370039, Len=1977): (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) 10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query 1 MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQ 80
WD40-rpts (__________________WD 1_______
Query 81 VGKEPYICIWDSYTVQTISVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDL 160
WD40-rpts __________) (__________________WD 2__________________) (_________________WD
Query 161 YQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHAAGI 240
WD40-rpts 3________________) (________________WD 4________________)(_______________
Query 241 FSMNACEEGFATGGRDGCIRLWDLTFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVQERNKPFLIM 320
WD40-rpts __WD 5________________) (______
Query 321 QGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNADGIHLALGMKDGSFTVLRVRDMTE 400
WD40-rpts ___________WD 6_________________) (_________________WD 7________________) (__
Query 401 VVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECLGSLSFITHLDWSSDSRYLQTNDGNGKRLFYRM 480
WD40-rpts _______________WD 8________________)(___________________WD 9__________________)
Query 481 PGGKEVTSTEEIKGVHWASWTCVSGLEVNGIWPKYSDINDINSVDGNYIGQVLVTADDYGIIKLFRYPCLRKGAKFRKYI 560
WD40-rpts (___________________WD10___________________) (_______
Query 561 GHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDAVHIAPQESLADSHSDESDSDLSDVPELDSEIEQETQLT 640
WD40-rpts __________WD11_________________)(______________WD12_____________)(______________
Query 641 YRRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQ 720
WD40-rpts ______WD13___________________) (___
Query 721 RFYLGHDDDILCLTIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGHHQYGVSAVDFSADGKRLASVGIDDSHTVVL 800
WD40-rpts _______________WD14_________________) (__________________WD15_________________
Query 801 WDWKKGEKLSIARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRKAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFS 880
WD40-rpts _) (_________________WD16________________)(_____________________WD17__________
Query 881 GTSTGDVCIWRDIFLVKTVKAHDGPVFSMHALEKGFVTGGKDGIVALWDDSFERCLKTYAIKRAALAPGSKGLLLEDNPS 960
WD40-rpts __________)(________________WD18________________) (________________
Query 961 IRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLK 1040
WD40-rpts __WD19_________________) (_________________WD20________________) (__________
Query 1041 KGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDMISDIRFSPGSGKYLAVASHDSFIDIYNVMSSKRVGI 1120
WD40-rpts _______WD21________________) (_________________WD22_________________) (_____
Query 1121 CKGATSYITHIDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKIAWASWTSVLGLCCEGIWPVIGEVTDVTASC 1200
WD40-rpts ____________WD23________________) (_________________
Query 1201 LTSDKMVLATGDDLGFVKLFRYPTKGKFGKFKRYVAHSTHVTNVRWTYDDSMLVTLGGTDMSLMVWTNEMEGYREKRPCD 1280
WD40-rpts WD24________________) (_________________WD25_________________) (__________
Query 1281 SEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGIKPHLQQKEPSIDERQGVVRGSRPPVSRAPPQPEKLQTNN 1360
WD40-rpts _______WD26________________) (_____________________WD27_____________________)
Query 1361 VGKKKRPIEDLVLELIFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGSQSFYQEHNDDILCLTVNQHPKFINIV 1440
WD40-rpts (__________________W
Query 1441 ATGQVGDSADMSATAPSIHIWDAMNKQTLSILRCYHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGAKIASRAGH 1520
WD40-rpts D28__________________) (__________________WD29__________________) (_________
Query 1521 NQRIFVAEFRPDSDTQFVSVGVKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAIAFGANNLTFTGTISGDVCVWKDHI 1600
WD40-rpts ________WD30________________) (________________WD31________________)(__
Query 1601 LCRIVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQATDCVRSVCRGKGKILVGTRN 1680
WD40-rpts ___________________WD32____________________)(___________________WD33____________
Query 1681 AEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAI 1760
WD40-rpts _______) (_________________WD34_________________)(__________________WD35_______
Query 1761 GMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSA 1840
WD40-rpts __________) (_________________WD36________________) (_______________WD
Query 1841 DSSYLQVSSGCYKRHVYEVPSGKHLMDHAAIDRITWATWTSILGDEVLGIWSRHAEKADVNCACVSHSGISLVTGDDFGM 1920
WD40-rpts 37_______________) (___________________WD38______________
Query 1921 VKLFDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCVHTPH 1977
WD40-rpts ____) (_________________WD39_________________)
 39 WD40-repeats found in QUERY=ENSP00000370039 (Len=1977): (Red - Z-score>4.0) Rpts Segment Boundary Z-score Score P-value Identities SS-score WD 1: Seg 5 51-91 6.56 385.71 0.00039 20.0% 56.54 WD 2: Seg 9 95-136 6.42 379.86 0.00047 37.5% 56.57 WD 3: Seg 13 140-178 7.21 412.44 0.00017 22.5% 56.81 WD 4: Seg 17 187-224 4.88 316.14 0.00341 20.0% 47.52 WD 5: Seg 21 225-263 6.61 387.89 0.00037 30.0% 50.25 WD 6: Seg 29 314-353 7.09 407.41 0.00020 22.5% 58.13 WD 7: Seg 33 356-394 6.65 389.48 0.00035 20.0% 56.85 WD 8: Seg 37 398-436 7.79 436.63 8.1e-05 17.5% 58.73 WD 9: Seg 41 437-479 6.98 402.83 0.00023 17.5% 58.02 WD10: Seg 47 503-546 6.43 380.28 0.00047 20.0% 48.87 WD11: Seg 51 553-592 6.95 401.56 0.00024 32.5% 53.13 WD12: Seg 55 593-625 3.54 260.89 0.01883 12.5% 18.74 WD13: Seg 57 626-670 4.55 302.64 0.00519 12.5% 16.70 WD14: Seg 62 717-757 6.15 368.85 0.00067 22.5% 55.57 WD15: Seg 66 761-802 6.41 379.31 0.00048 47.5% 57.01 WD16: Seg 70 806-844 6.43 380.25 0.00047 20.0% 55.68 WD17: Seg 74 845-891 5.81 354.76 0.00103 12.5% 51.69 WD18: Seg 78 892-929 7.68 432.08 9.3e-05 27.5% 50.45 WD19: Seg 83 944-984 4.16 286.49 0.00855 12.5% 31.14 WD20: Seg 86 988-1026 6.58 386.56 0.00038 20.0% 55.57 WD21: Seg 90 1030-1068 7.62 429.22 0.00010 30.0% 58.67 WD22: Seg 94 1072-1111 6.55 385.22 0.00040 27.5% 57.29 WD23: Seg 98 1115-1153 6.69 390.82 0.00034 17.5% 56.42 WD24: Seg104 1183-1221 6.59 386.96 0.00038 22.5% 50.51 WD25: Seg108 1228-1267 6.35 376.83 0.00052 27.5% 49.20 WD26: Seg112 1270-1308 5.19 329.01 0.00229 15.0% 42.81 WD27: Seg116 1311-1358 5.07 324.15 0.00266 17.5% 19.55 WD28: Seg123 1421-1462 7.09 407.50 0.00020 17.5% 53.02 WD29: Seg127 1466-1507 6.14 368.35 0.00068 45.0% 56.49 WD30: Seg131 1511-1549 7.19 411.66 0.00018 20.0% 56.26 WD31: Seg136 1560-1597 5.37 336.56 0.00181 15.0% 43.09 WD32: Seg139 1598-1644 6.14 368.44 0.00067 22.5% 51.35 WD33: Seg143 1645-1688 5.80 354.31 0.00104 20.0% 50.88 WD34: Seg147 1691-1730 7.35 418.09 0.00014 30.0% 56.63 WD35: Seg151 1731-1771 5.82 354.88 0.00103 15.0% 56.38 WD36: Seg155 1775-1813 7.72 433.68 8.9e-05 20.0% 58.67 WD37: Seg160 1823-1858 5.97 361.38 0.00084 20.0% 44.92 WD38: Seg165 1883-1925 6.79 395.24 0.00029 25.0% 49.23 WD39: Seg169 1932-1971 6.30 374.87 0.00055 27.5% 51.97Multiple sequence alignment of 39 WD40-repeats: (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) WD 1 51-91 EH-------R---------QKF----YR-G-HSD-D-IISLALHP-E--------RVLVAT-GQVGKE------P--YICIWD WD 2 95-136 -V-------Q---T-----ISV----LK-DVHTH-G-IACLAFDL-D--------GQRLVS-VG--LD----SKN--AVCVWD WD 3 140-178 -G-------K---M-----LSM----AP-G-HTD-R-IFDISWDL-Y--------QPNKLV-SC--GV------K--HIKFWS WD 4 187-224 -K-------R---G-----VFG----KT-G-DLQ-T-ILCLACAR-D--------E-LTYS-GA--LN------G--DIYVWK WD 5 225-263 GI-------N---L-----IRT---IQG-A-HAA-G-IFSMNACE-E--------G--FAT-GG--RD------G--CIRLWD WD 6 314-353 -N-------K---P-----FLI----MQ-G-HCE-GELWALAVHP-T--------KPLAVT-GS--DD------R--SVRIWS WD 7 356-394 -D-------H---A-----LIA----RC-N-MEE-P-IRCAAVNA-D--------GIHLAL-GM--KD------G--SFTVLR WD 8 398-436 -M-------T---E-----VVH----IK-D-RKE-A-IHELKYSP-D--------GTYLAV-GC--ND------S--SVDIYG WD 9 437-479 VA----QRYK---K-----VGE----CL-G-SLS-F-ITHLDWSS-D--------SRYLQT-ND--GN------G--KRLFYR WD10 503-546 VS-------G---L-----EVNGIWPKY-S-DIN-D-INSVDGNY-I--------GQVLVT-AD--DY------G--IIKLFR WD11 553-592 -G-------A---K-----FRK----YI-G-HSA-H-VTNVRWSH-D--------YQWVISIGG--AD------H--SVFQWK WD12 593-625 --------------------------FI-P-ERK-L-KDAVHIAP-Q--------ESLADS-HS--DE------S--DSDLSD WD13 626-670 VP-------E---LDSEIEQET----QL-T-YRR-Q-VYKEDLPQ-L--------KEQCKE-KQ--KS------A--TSKRRE WD14 717-757 -Q-------N---T-----QRF----YL-G-HDD-D-ILCLTIHP-L--------KDYVAT-GQVGRD------P--SIHIWD WD15 761-802 -I-------K---P-----LSI----LK-G-HHQYG-VSAVDFSA-D--------GKRLAS-VG--ID------DSHTVVLWD WD16 806-844 -G-------E---K-----LSI----AR-G-SKD-K-IFVVKMNP-Y--------VPDKLI-TA--GI------K--HMKFWR WD17 845-891 KAGGGLIGRK---G-----YIG----TL-G-KND-T-MMCAVYGW-T--------EEMAFS-GT--ST------G--DVCIWR WD18 892-929 DI-------F---L-----VKT----VK-A-HDG-P-VFSMHALE-K--------G--FVT-GG--KD------G--IVALWD WD19 944-984 AA-------L---A-----PGS----KGLL-LED-N-PSIRAISL-G--------HGHILV-GT--KN------G--EILEVD WD20 988-1026 -P-------I---T-----LLV----QG-H-MEG-E-VWGLATHP-Y--------LPICAT-VS--DD------K--TLRIWD WD21 1030-1068 -S-------H---C-----MLA----VR-K-LKK-G-GRCCCFSP-D--------GKALAV-GL--ND------G--SFLMAN WD22 1072-1111 -L-------E---D-----LVS----FH-H-RKD-M-ISDIRFSPGS--------GKYLAV-AS--HD------S--FIDIYN WD23 1115-1153 -S-------K---R-----VGI----CK-G-ATS-Y-ITHIDWDI-R--------GKLLQV-NT--GA------K--EQLFFE WD24 1183-1221 -C-------E---G-----IWP----VI-G-EVT-D-VTASCLTS-D--------KMVLAT-GD--DL------G--FVKLFR WD25 1228-1267 -F-------G---K-----FKR----YV-A-HST-H-VTNVRWTY-D--------DSMLVTLGG--TD------M--SLMVWT WD26 1270-1308 -M-------E---G-----YRE----KR-P-CDS-E-ESDIDSEE-D--------GGYDSD-VT--RE------N--EISYTI WD27 1311-1358 LS-------T---N-----IRP----ML-G-IKP-H-LQQKEPSI-DERQGVVRGSRPPVS-RA--PP------Q--PEKLQT WD28 1421-1462 HN-------D-DIL-----CLT----VN-Q-HPK-F-INIVATGQ-V--------GDSADM-SA--TA------P--SIHIWD WD29 1466-1507 -K-------Q---T-----LSI----LR-CYHSK-G-VCSVSFSA-T--------GKLLLS-VG--LD----PEH--TITIWR WD30 1511-1549 -G-------A---K-----IAS----RA-G-HNQ-R-IFVAEFRP-D--------SDTQFV-SV--GV------K--HVKFWT WD31 1560-1597 -G-------L---L-----STL----ED-A-RMQ-T-MLAIAFGA-N--------NLTF-T-GT--IS------G--DVCVWK WD32 1598-1644 DH-------I--LC-----RIV----AR-A-HNG-P-VFAMYTTL-R--------DGLIVT-GG--KERPSKEGG--AVKLWD WD33 1645-1688 QE---LRRCR---A-----FRL----ET-G-QAT-D-CVRSVCRG-K--------GKILVG-TR--NA------E--IIEVGE WD34 1691-1730 -A-------A---C-----NIL----VN-G-HVD-GPIWGLATHP-S--------RDFFLS-AA--ED------G--TVRLWD WD35 1731-1771 IA-------D--KK-----MLN----KV-N-LGH-A-ARTVCYSP-E--------GDMVAI-GM--KN------G--EFIILL WD36 1775-1813 -L-------K---I-----WGK----KR-D-RRC-A-IHDIRFSP-D--------SRYLAV-GS--SE------N--SVDFYD WD37 1823-1858 -------------------ISY----CK-D-IPS-F-VIQMDFSA-D--------SSYLQV-SS--GC------Y--KRHVYE WD38 1883-1925 LG-------DEVLG-----IWS----RH-A-EKA-D-VNCACVSH-S--------GISLVT-GD--DF------G--MVKLFD WD39 1932-1971 -F-------A---K-----HKR----FL-G-HSP-H-VTNIRFTS-G--------DRHVVSAGG--DD------C--SLFVWK WD40 Template TG-------E---C-----LRT----LS-G-HTS-G-VTSVSFSP-D--------GKRLVS-GS--ED------G--TIKVWD |
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