WDRR: WD40 Repeat Recognition
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| Pre-calculated Results - Accession: ENSP00000381627 [Homo sapiens] [Download result as txt] [Query sequence in FASTA]
Input parameters:
Query = ENSP00000381627 (Len=1874) Tmplt = WD40-str (Len=40) Method = bdp Gap-open = 50 Gap-extend = 3 Database = /home/pub/blastdb/nr90 E-value = 0.001 Iteration = 3Query sequence (ENSP00000381627, Len=1874): (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) 10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query 1 MADRTAPRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLALHPDKTLVATGQ 80
WD40-rpts (___________________WD 1________
Query 81 VGKEPYICIWDSYNVQTVSLLKDVHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDP 160
WD40-rpts __________)(____________________WD 2___________________) (_________________WD
Query 161 YQPNRVVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGI 240
WD40-rpts 3________________) (________________WD 4________________)(_______________
Query 241 FSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERDKPMLIL 320
WD40-rpts __WD 5________________) (__________________WD 6_________________) (______
Query 321 QGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVAFSPDGSQLALGMKDGSFIVLRVRDMTE 400
WD40-rpts ___________WD 7_________________)(__________________WD 8_________________) (__
Query 401 VVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKIGECSKSLSFITHIDWSLDSKYLQTNDGAGERLFYRM 480
WD40-rpts _______________WD 9________________) (_________________WD10________________)
Query 481 PSGKPLTSKEEIKGIPWASWTCVKGPEVSGIWPKYTEVTDINSVDANYNSSVLVSGDDFGLVKLFKFPCLKRGAKFRKYV 560
WD40-rpts (_________________WD11________________) (_______
Query 561 GHSAHVTNVRWSHDFQWVLSTGGADHSVFQWRFIPEGVSNGMLETAPQEGGADSYSEESDSDLSDVPELDSDIEQEAQIN 640
WD40-rpts __________WD12_________________) (_________________WD13________
Query 641 YDRQVYKEDLPQLKQQSKEKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQHSQ 720
WD40-rpts ________) (___
Query 721 RLYLGHDDDILSLTIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLVSVGLDDFHSIVF 800
WD40-rpts _______________WD14_________________) (__________________WD15_________________
Query 801 WDWKKGEKIATTRGHKDKIFVVKCNPHHVDKLVTVGIKHIKFWQQAGGGFTSKRGTFGSVGKLETMMCVSYGRMEDLVFS 880
WD40-rpts _) (_________________WD16________________) (________________WD17_____
Query 881 GAATGDIFIWKDILLLKTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRSALSTSSKGLLLEDNPS 960
WD40-rpts __________)(________________WD18________________) (___________________
Query 961 IRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSAQHRMLAVRKLK 1040
WD40-rpts WD19___________________) (_________________WD20________________) (__________
Query 1041 KGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSKDTGKYLAVASHDNFVDIYNVLTSKRVGI 1120
WD40-rpts _______WD21________________) (_________________WD22_________________) (_____
Query 1121 CKGASSYITHIDWDSRGKLLQVNSGAREQLFFEAPRGKRHIIRPSEIEKIEWDTWTCVLGPTCEGIWPAHSDITDVNAAS 1200
WD40-rpts ____________WD23________________) (_________________
Query 1201 LTKDCSLLATGDDFGFVKLFSYPVKGQHARFKKYVGHSAHVTNVRWLHNDSVLLTVGGADTALMIWTREFVGTQESKLVD 1280
WD40-rpts WD24________________) (_________________WD25_________________)
Query 1281 SEESDTDVEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERPPVSRAAPQPEKLQKNNITKKKKLV 1360
WD40-rpts (____________________WD26___________________
Query 1361 EELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTT 1440
WD40-rpts ) (________________WD27_______________)(____________________WD28______________
Query 1441 PSIHIWDAMTKHTLSMLRCFHSKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDT 1520
WD40-rpts ______) (__________________WD29_________________) (_________________WD30___
Query 1521 QFVSVGVKHMKFWTLAGSALLYKKGVIGSLGAAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLIRLVAKAHTGPVFT 1600
WD40-rpts _____________) (_______________WD31_______________)(_________________
Query 1601 MYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGKILVGTKDGEIIEVGEKNAASNI 1680
WD40-rpts ____WD32____________________)(___________________WD33___________________) (____
Query 1681 LIDGHMEGEIWGLATHPSKDLFISASNDGTARIWDLADKKLLNKVSLGHAARCAAYSPDGEMVAIGMKNGEFVILLVNSL 1760
WD40-rpts _____________WD34_________________)(__________________WD35_________________) (
Query 1761 KVWGKKRDRKSAIQDIRISPDNRFLAVGSSEHTVDFYDLTQGTNLNRIGYCKDIPSFVIQMDFSADGKYIQMQLTLLVGN 1840
WD40-rpts _________________WD36________________) (____________________WD37________
Query 1841 HTQRTAILGLWKIARKWMRRKMGKWPAVVVMGWP 1874
WD40-rpts ___________)
 37 WD40-repeats found in QUERY=ENSP00000381627 (Len=1874): (Red - Z-score>4.0) Rpts Segment Boundary Z-score Score P-value Identities SS-score WD 1: Seg 4 49-91 6.61 387.53 0.00037 27.5% 53.90 WD 2: Seg 8 92-136 6.38 378.11 0.00050 35.0% 55.83 WD 3: Seg 12 140-178 7.44 421.87 0.00013 25.0% 56.64 WD 4: Seg 16 187-224 4.91 317.50 0.00327 17.5% 49.52 WD 5: Seg 20 225-263 6.83 396.85 0.00028 30.0% 52.85 WD 6: Seg 24 270-310 3.51 259.56 0.01961 25.0% 40.46 WD 7: Seg 27 314-353 7.20 412.05 0.00017 25.0% 58.99 WD 8: Seg 31 354-394 7.45 422.59 0.00013 35.0% 58.36 WD 9: Seg 35 398-436 8.06 447.57 5.8e-05 27.5% 58.72 WD10: Seg 39 441-479 6.90 399.50 0.00026 20.0% 55.72 WD11: Seg 45 508-546 6.80 395.67 0.00029 20.0% 39.67 WD12: Seg 48 553-592 6.68 390.79 0.00034 32.5% 51.74 WD13: Seg 52 611-649 4.24 289.71 0.00774 10.0% 39.25 WD14: Seg 59 717-757 6.57 386.24 0.00039 27.5% 50.38 WD15: Seg 63 761-802 6.74 393.13 0.00031 47.5% 56.93 WD16: Seg 67 806-844 6.99 403.45 0.00023 25.0% 56.62 WD17: Seg 72 855-891 6.24 372.49 0.00059 20.0% 43.82 WD18: Seg 75 892-929 8.06 447.71 5.8e-05 27.5% 52.79 WD19: Seg 80 941-984 3.28 250.09 0.02623 12.5% 44.54 WD20: Seg 84 988-1026 6.70 391.46 0.00033 17.5% 54.90 WD21: Seg 88 1030-1068 7.59 428.23 0.00011 30.0% 58.73 WD22: Seg 92 1072-1111 6.57 386.20 0.00039 22.5% 57.30 WD23: Seg 96 1115-1153 6.78 394.66 0.00030 17.5% 56.25 WD24: Seg102 1183-1221 6.42 380.04 0.00047 20.0% 41.84 WD25: Seg105 1228-1267 6.18 369.90 0.00064 25.0% 51.99 WD26: Seg113 1317-1361 3.04 240.03 0.03566 10.0% 13.25 WD27: Seg116 1365-1401 3.01 239.13 0.03666 12.5% 49.03 WD28: Seg120 1402-1447 4.51 300.85 0.00548 25.0% 55.99 WD29: Seg124 1452-1492 6.02 363.41 0.00079 37.5% 58.25 WD30: Seg128 1496-1534 7.27 415.00 0.00016 22.5% 56.22 WD31: Seg133 1547-1582 5.10 325.52 0.00255 20.0% 43.92 WD32: Seg136 1583-1629 6.00 362.35 0.00081 25.0% 50.73 WD33: Seg140 1630-1673 5.63 347.09 0.00131 17.5% 44.74 WD34: Seg144 1676-1715 7.09 407.51 0.00020 27.5% 55.73 WD35: Seg148 1716-1756 6.13 367.96 0.00068 17.5% 56.24 WD36: Seg152 1760-1798 7.91 441.23 7.0e-05 22.5% 59.16 WD37: Seg157 1808-1852 4.85 314.95 0.00354 25.0% 35.77Multiple sequence alignment of 37 WD40-repeats: (BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED) WD 1 49-91 TR----E--HSQK-FF-L-----G-H----ND-D-IISLAL-H--PD-KT-LVA---------TG--QVGKE------P--Y---ICIWD WD 2 92-136 SY----NVQTVSL-LK-D-----V-H----TH-G-VACLAF-D--SD-GQ-RLA---------SV--G--LD------AKNT---VCIWD WD 3 140-178 -G----K---LLA-SA-T-----G-H----SD-R-IFDISW-D--PY-QP-NRV---------VS--C--GV------K--H---IKFWT WD 4 187-224 -K----R---GIF-GK-T-----G-D----LQ-T-ILCLAC-A--KE-D--ITY---------SG--A--LN------G--D---IYVWK WD 5 225-263 GL----N---LVR-TIQG-----A-H----SA-G-IFSMYA-C--EE-G---FA---------TG--G--RD------G--C---IRLWD WD 6 270-310 TK----I---DLRETE-Q-----G-Y----KGLS-IRSVCW-K--AD-R--LLA---------GT--Q--DS------E--I---FEVIV WD 7 314-353 -D----K---PML-IL-Q-----G-H----CE-GELWALAL-H--PK-KP-LAV---------TG--S--DD------R--S---VRLWS WD 8 354-394 LA----D--HALI-AR-C-----N-M----EE-A-VRSVAF-S--PD-GS-QLA---------LG--M--KD------G--S---FIVLR WD 9 398-436 -M----T---EVV-HI-K-----D-R----KE-V-IHEMKF-S--PD-GS-YLA---------VG--S--ND------G--P---VDVYA WD10 441-479 -Y----K---KIG-EC-S-----K-S----LS-F-ITHIDW-S--LD-SK-YLQ---------TN--D--GA------G--E---RLFYR WD11 508-546 VS----G----IW-PK-Y-----T-E----VT-D-INSVDA-N--YN-SS-VLV---------SG--D--DF------G--L---VKLFK WD12 553-592 -G----A---KFR-KY-V-----G-H----SA-H-VTNVRW-S--HD-FQWVLS---------TG--G--AD------H--S---VFQWR WD13 611-649 -G----A---DSY-SE-E-----S-D----SD-L-SDVPEL-D--SD-IE-QEA---------QI--N--YD------R--Q---VYKED WD14 717-757 -Q----H---SQR-LY-L-----G-H----DD-D-ILSLTI-H--PV-KD-YVA---------TGQVG--RD------A--A---IHVWD WD15 761-802 -L----K---CLS-LL-K-----GQH----QR-G-VCALDF-S--AD-GK-CLV---------SV--G--LD------DFHS---IVFWD WD16 806-844 -G----E---KIA-TT-R-----G-H----KD-K-IFVVKC-N--PH-HV-DKL---------VT--V--GI------K--H---IKFWQ WD17 855-891 ----------GTF-GS-V-----G-K----LE-T-MMCVSY-G--RM-ED-LVF---------SG--A--AT------G--D---IFIWK WD18 892-929 DI----L---LLK-TV-K-----A-H----DG-P-VFAMYA-L--DK-G---FV---------TG--G--KD------G--I---VELWD WD19 941-984 IK----R---SAL-ST-S-----S-KGLLLED-N-PSIRAI-T--LG-HG-HIL---------VG--T--KN------G--E---ILEID WD20 988-1026 -P----M---TLL-VQ-G-----H-M----EG-E-VWGLAA-H--PL-LP-ICA---------TV--S--DD------K--T---LRIWE WD21 1030-1068 -Q----H---RML-AV-R-----K-L----KK-G-GRCCAF-S--PD-GK-ALA---------VG--L--ND------G--S---FLVVN WD22 1072-1111 -V----E---DMV-SF-H-----H-R----KE-M-ISDIKF-S--KDTGK-YLA---------VA--S--HD------N--F---VDIYN WD23 1115-1153 -S----K---RVG-IC-K-----G-A----SS-Y-ITHIDW-D--SR-GK-LLQ---------VN--S--GA------R--E---QLFFE WD24 1183-1221 -C----E---GIW-PA-H-----S-D----IT-D-VNAASL-T--KD-CS-LLA---------TG--D--DF------G--F---VKLFS WD25 1228-1267 -H----A---RFK-KY-V-----G-H----SA-H-VTNVRWLH--ND-SV-LLT---------VG--G--AD------T--A---LMIWT WD26 1317-1361 EM----E---GTK-PH-QQLKEVS-V----EE-R-PPVSRA-A--PQ-PE-KLQ---------KN--N--IT------K--K---KKLVE WD27 1365-1401 -L----D---HVF-GY-R-----G-F----DC---RNNLHY-L--ND-GA-DII---------FH--T--AA------A--G---I-VQN WD28 1402-1447 LS----T--GSQS-FY-L-----E-H----TD-D-ILCLTV-NQHPK-YR-NVV---------AT--S--QI------G--TTPSIHIWD WD29 1452-1492 -H----T---LSM-LR-C-----F-H----SK-G-VNYINF-S--AT-GK-LLV---------SV--G--VD----PEH--T---ITVWR WD30 1496-1534 -G----A---KVA-SR-G-----G-H----LE-R-IFVVEF-R--PD-SD-TQF---------VS--V--GV------K--H---MKFWT WD31 1547-1582 IG----S-------LG-A-----A-K----MQ-T-MLSVAF-G--AN-N--LTF---------TG--A--IN------G--D---VYVWK WD32 1583-1629 DH----F---LIRLVA-K-----A-H----TG-P-VFTMYT-T--LR-DG-LIV---------TG--G--KERPTKEGG--A---VKLWD WD33 1630-1673 QEMKRCR---AFQ-LE-T-----G-Q----LV-E-CVRSVC-R--GK-GK-ILV---------GT--K--DG------E--I---IEVGE WD34 1676-1715 -A----A---SNI-LI-D-----G-H----ME-GEIWGLAT-H--PS-KD-LFI---------SA--S--ND------G--T---ARIWD WD35 1716-1756 LA----D--KKLL-NK-V-----S-L----GH-A-ARCAAY-S--PD-GE-MVA---------IG--M--KN------G--E---FVILL WD36 1760-1798 -L----K---VWG-KK-R-----D-R----KS-A-IQDIRI-S--PD-NR-FLA---------VG--S--SE------H--T---VDFYD WD37 1808-1852 IG----Y---C------K-----D-I----PS-F-VIQMDF-S--AD-GK-YIQMQLTLLVGNHT--Q--RT------A--I---LGLWK WD40 Template TG----E---CLR-TL-S-----G-H----TS-G-VTSVSF-S--PD-GK-RLV---------SG--S--ED------G--T---IKVWD |
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