Accession: ENSMUSP00000013130 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000013130 (Len=796)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000013130, Len=796):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MDELAGGGGGGQGMAAPPRPQQGPGGNLSLPPGANGAPGGGGPPAAEAAGPPAGPELSRPQQYTIPGILHYIQHEWARFE 80  
WD40-rpts                                                                                      

Query       81 MERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDVE 160 
WD40-rpts                                                                                      

Query      161 APPAPQNSQLTWKQGRQLLRQYLQEVGYTDTILDVRSQRVRSLLGLSNSEPNGSVEAKNLEQILNGGESPKQKGQEIKRP 240 
WD40-rpts                                                                                      

Query      241 PGDVLETFNFLENADDSDEEENDMIEGIPEGKDKLRIHKHKIGNEGLAADLTDDPDTEEALKEFDFLVTAEDGEGAGEAR 320 
WD40-rpts                             (____________________________________WD 1________________

Query      321 SSGDGTEWDKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTNLCDMITDLGDDELPHIPSGIINQSRSAST 400 
WD40-rpts      ____________________)               (______________WD 2_____________)           

Query      401 RMADHEGARAEEAEPITFPSGGGKSFIMGSDDVLLSVLGLGDLADLTVTNDADYSYDLPANKDAFRKTWNPKYTLRSHFD 480 
WD40-rpts                                   (__________________WD 3_________________)__________

Query      481 GVRALAFHPVEPVLVTASEDHTLKLWNLQKTVPAKKSASLDVEPIYTFRAHIGPVLSLAISSNGEQCFSGGIDATIQWWN 560 
WD40-rpts      ______WD 4________________)              (_________________WD 5________________)

Query      561 MPSPNVDPYDTYESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQEKLPCVCTYNGDKEHGIPTSVDFIG 640 
WD40-rpts                    (_________________WD 6________________)(____________________WD 7__

Query      641 CDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVA 720 
WD40-rpts      __________________)          (_________________WD 8________________)   (________

Query      721 HLDAVTSLAVDPNGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDESIYDVAFHPSKAYIASAGADALAKVFV 796 
WD40-rpts      _________WD 9________________)   (___________________WD10__________________)

10 WD40-repeats found in QUERY=ENSMUSP00000013130 (Len=796):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1   264-341      5.03  322.42  0.00281       22.5%     25.27
  WD 2:  Seg  4   357-389      3.67  266.18  0.01600       10.0%     10.35
  WD 3:  Seg  8   430-470      6.56  385.46  0.00040       15.0%     40.63
  WD 4:  Seg 11   469-507      9.16  493.24  1.4e-05       37.5%     46.45
  WD 5:  Seg 15   522-560      8.38  460.95  3.8e-05       32.5%     51.74
  WD 6:  Seg 19   575-613      8.53  467.06  3.2e-05       35.0%     45.04
  WD 7:  Seg 22   614-659      5.74  351.84  0.00113       22.5%     49.65
  WD 8:  Seg 27   670-708      6.59  386.74  0.00038       17.5%     43.79
  WD 9:  Seg 30   712-750      9.88  522.86  5.6e-06       35.0%     56.44
  WD10:  Seg 34   754-796      6.71  391.69  0.00033       22.5%     50.46

Multiple sequence alignment of 10 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  264-341    MIE---GIPEGKDKLRIHKHKIGNEGLAADLTDDPDTEEALKEFDFLVT-AEDG----EGAGEAR---SSGDGTEWDKDDLSPTAEVWD
   WD 2  357-389    ------------------------------------------------E-RKGK----KGVKRVN---RTNLCDMITDLGDDELPHIPS
   WD 3  430-470    SDD---VL---------------------------L-----------SVLGLGD----LADLTVT---NDADYSYDLPANKDAFRKTWN
   WD 4  469-507    -WN---PK---------------------------Y-----------TL-RSHF----DGVRALA---FHPVEPVLVTASEDHTLKLWN
   WD 5  522-560    -VE---PI---------------------------Y-----------TF-RAHI----GPVLSLA---ISSNGEQCFSGGIDATIQWWN
   WD 6  575-613    -NV---LA---------------------------G-----------TL-VAHT----DAVWGLA---YSGIKNQLLSCSADGTIRLWN
   WD 7  614-659    PQEKLPCV---------------------------C-----------TY-NGDK----EHGIPTSVDFIGCDPAHMVTSFNTGSAVIYD
   WD 8  670-708    SSQ----V---------------------------D-----------SG-LQSS----NHINRVV---SHPTLPVTITAHEDRHIKFFD
   WD 9  712-750    -GK---MI---------------------------H-----------SM-VAHL----DAVTSLA---VDPNGIYLMSGSHDCSIRLWN
   WD10  754-796    -KT---CV---------------------------Q-----------EI-TAHRKKLDESIYDVA---FHPSKAYIASAGADALAKVFV

   WD40 Template    TGE---CL---------------------------R-----------TL-SGHT----SGVTSVS---FSPDGKRLVSGSEDGTIKVWD