Accession: ENSMUSP00000021645 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000021645 (Len=519)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000021645, Len=519):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MDRNIWKSRRRRGRSRHQSPALGQCDSSERYATGASQSSQDSGHHDAESPSTSSSRTGESSVPELPGFYFDPEKNRYFRL 80  
WD40-rpts                                                                                      

Query       81 LPGHNNCNPLTKEGIQQKEMESRRLQLLQQEDMQKKKITRVGFNASSILRKNQLGFLNFSSYCRLSHELRVSCMERKKVE 160 
WD40-rpts                                                                               (______

Query      161 IQSSDPSALASDRFNFIMADTTSDRLFTVNDVKIGGSKYGIINLQGLKAPTFEVQMHENLYFTNRKVNSVCWASLNHLDS 240 
WD40-rpts      __________WD 1________________)                                      (__________

Query      241 HILLCLMGLAETPGCATLLPASLFVSNHQAGTDQPGMLCSFRIPGAWSCAWSLNVQANNCFSTGLSRRVLLTNVVTGHRQ 320 
WD40-rpts      ________WD 2__________________)   (_________________WD 3________________)(______

Query      321 SYRINSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATQIFHDSAVTSVQVFKEEQHLMASDMSGKIKLWDL 400 
WD40-rpts      ___________WD 4_________________)(____________________WD 5____________________) 

Query      401 RATKCVRQYEGHVNEYAYLPLHMHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPCPTSKANIPSVAFSPRLGGSRGAP 480 
WD40-rpts        (__________________WD 6_________________)   (_________________WD 7____________

Query      481 GLLMAVQQDLYCFAYSSSCPDSQEEGRWELPSVSNEDIL 519 
WD40-rpts      ____)

7 WD40-repeats found in QUERY=ENSMUSP00000021645 (Len=519):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  2   154-191      5.68  349.22  0.00122       10.0%     11.91
  WD 2:  Seg  8   230-271      5.80  354.18  0.00105       15.0%     22.62
  WD 3:  Seg 10   275-313      7.71  433.30  9.0e-05        7.5%     55.90
  WD 4:  Seg 14   314-353      8.90  482.43  2.0e-05       22.5%     51.03
  WD 5:  Seg 18   354-399      8.69  473.75  2.6e-05       32.5%     47.27
  WD 6:  Seg 21   403-443      7.71  433.09  9.1e-05       20.0%     55.39
  WD 7:  Seg 25   447-485      5.03  322.39  0.00281       15.0%     10.42

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1  154-191    ---M------ERKKVEIQSS-DPS--ALASDRFNFIMADTTSDRLFTVND
   WD 2  230-271    VCWA------SLNHLDSHILLCLM--GLAETPGCATLLPASLFVSNHQAG
   WD 3  275-313    -P-G------MLCSFRIPGA-WSC--AWSLNVQANNCFSTGLSRRVLLTN
   WD 4  314-353    VV-T------GHRQSYRINS-DVL--AQQFAVKTPLLFNGCRSGEIFAID
   WD 5  354-399    LR-SPSQAKGWKATQIFHDS-AVT--SVQVFKEEQHLMASDMSGKIKLWD
   WD 6  403-443    -T-K------CVRQYEGHVN-EYAYLPLHMHEEEGILVAVGQDCYTRIWS
   WD 7  447-485    -A-R------LLRTIPSPCP-TSK--ANIPSVAFSPRLGGSRGAPGLLMA

   WD40 Template    TG-E------CLRTLSGHTS-GVT--SVSFSPDGKRLVSGSEDGTIKVWD