Accession: ENSMUSP00000023474 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000023474 (Len=358)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000023474, Len=358):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAVKWTGGHSSSILCLNANKDGLVASGGEGGDLVAWGEDGTPLGHMQLEGADDVTSVLFSASCPTKLYASHGETISVLDV 80  
WD40-rpts         (______________WD 1______________)   (_________________WD 2________________)(

Query       81 RSLKGSLDHFHVNEEEINCLSLNETESLLASADDSGAIKILDLEKKKVTRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQ 160 
WD40-rpts      ___________________WD 3__________________)   (_________________WD 4_____________

Query      161 VMLWSLQKARPVWITNLQEDETEETEGPQTPGRLLNPALAHSVSVASCGNIFSCGAEDGKVRIFRVMGVKCERELGFKGH 240 
WD40-rpts      ____)                     (_________________WD 5________________)   (___________

Query      241 TLGVSQVCFLPESSLLLTGGNDGRIRLWDVSGKMEKLQKSPARHIHRKKAKRAACPTQGGNSRAPGAEDEGHAKILPKLD 320 
WD40-rpts      _______WD 6_________________)         (__________________WD 7__________________)

Query      321 IEHGEKVNWLLSTKIKGNKSILVADQTSCVSVYPLNEL 358 
WD40-rpts

7 WD40-repeats found in QUERY=ENSMUSP00000023474 (Len=358):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg  1     4-37       7.31  416.47  0.00015       25.0%     46.12
  WD 2:  Seg  4    41-79       8.51  466.35  3.2e-05       27.5%     55.72
  WD 3:  Seg  8    80-122      8.37  460.52  3.9e-05       20.0%     52.23
  WD 4:  Seg 12   126-165      8.27  456.11  4.4e-05       30.0%     57.07
  WD 5:  Seg 17   187-225      7.75  434.61  8.6e-05       22.5%     42.43
  WD 6:  Seg 20   229-269      9.35  500.99  1.1e-05       45.0%     59.20
  WD 7:  Seg 25   279-320      6.28  374.25  0.00056       12.5%     41.20

Multiple sequence alignment of 7 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1    4-37     --------KWT--GGHSSSILCLNANKD-G-LVASGGEG----GDLVAWG
   WD 2   41-79     -TP---LGHMQ--LEGADDVTSVLFSAS-CPTKLYASHG----ETISVLD
   WD 3   80-122    VRSLKGSLDHF--HVNEEEINCLSLNET-ESLLASADDS----GAIKILD
   WD 4  126-165    -KK---VTRSL--KRHSNICSSVAFRPQRPQSLVSCGLD----MQVMLWS
   WD 5  187-225    -GP---QTPGR--LLNPALAHSVSVASC-GNIFSCGAED----GKVRIFR
   WD 6  229-269    -VK---CERELGFKGHTLGVSQVCFLPE-SSLLLTGGND----GRIRLWD
   WD 7  279-320    --K---SPARH--IHRKKAKRAACPTQG-GNSRAPGAEDEGHAKILPKLD

   WD40 Template    TGE---CLRTL--SGHTSGVTSVSFSPD-GKRLVSGSED----GTIKVWD