Accession: ENSMUSP00000066911 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000066911 (Len=1573)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000066911, Len=1573):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MIGNKEENNKQVILKIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGY 80  
WD40-rpts                                                                                      

Query       81 NATVFAYGQTGAGKTYTMGTGFDVNIMEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLF 160 
WD40-rpts                                                                                      

Query      161 DTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240 
WD40-rpts                                                                                      

Query      241 PQTDAENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATH 320 
WD40-rpts                                                                                      

Query      321 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMEL 400 
WD40-rpts                                                                                      

Query      401 MEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRARITQLVSEQANQVLARAGEGNEEISNMIH 480 
WD40-rpts                                                                                      

Query      481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSASSAFSPTILSSDKETIEIIDLAKKDLEKLKRKEKKKKKSVA 560 
WD40-rpts                                                                                      

Query      561 GKDDNADTDQEKKEEKGVSEKENNELDVEENQEVSDHEDEEEEEEDEEEEDDIEGEESSDESDSESDEKANYQADLANIT 640 
WD40-rpts                                                                                      

Query      641 CEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVKCEYEKKLHAMNKE 720 
WD40-rpts                                                                                      

Query      721 LQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRL 800 
WD40-rpts                                                                                      

Query      801 LEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSESPAPDTGSSAASGEADTSRPGTQQKMRIPVARVQA 880 
WD40-rpts                                                                                      

Query      881 LPTPTTNGTRKKYQRKGFTGRVFTSKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLRQREELTKRREKLSKRREKI 960 
WD40-rpts                                                                                      

Query      961 VKESGEGDKSVANIIEEMESLTANIDYINDSIADCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINK 1040
WD40-rpts                                                                                      

Query     1041 GLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQENEEDSSEEDGPLHSPGSEGSTLSS 1120
WD40-rpts                                                                                      

Query     1121 DLMKLCGEVKPKNKARRRTTTQMELLYADSSEVASDTSAGDASLSGPLAPVAEGQEIGMNTETSGTSARDKELLAPSGLP 1200
WD40-rpts                                                                                      

Query     1201 SKIGSMSDESDSSLSEVHRGIINPFPACKGVRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIM 1280
WD40-rpts                                              (_____________WD 1_____________)        

Query     1281 SLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNP 1360
WD40-rpts       (_____________WD 2_____________)                                               

Query     1361 TGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPP 1440
WD40-rpts                       (____________________WD 3___________________)(_________________

Query     1441 HYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGE 1520
WD40-rpts      ___WD 4____________________)                                              (_____

Query     1521 MRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGEDIASN 1573
WD40-rpts      ___________WD 5_______________)

5 WD40-repeats found in QUERY=ENSMUSP00000066911 (Len=1573):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 14  1241-1272     4.53  301.69  0.00534       37.5%     17.73
  WD 2:  Seg 16  1282-1313     2.88  233.78  0.04314       27.5%     38.99
  WD 3:  Seg 21  1378-1422     3.94  277.27  0.01136       27.5%     36.11
  WD 4:  Seg 24  1423-1468     3.74  269.27  0.01455       32.5%     22.18
  WD 5:  Seg 27  1515-1551     3.28  250.13  0.02619       15.0%     31.58

Multiple sequence alignment of 5 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1241-1272   IAE--------G--------HTKAVLCVDSTDD-----LLFTGSKDRTCKVWN
   WD 2 1282-1313   ---------LGV--------HPNNVVSVKYCNYTS---LVFTVST-SYIKVWD
   WD 3 1378-1422   LKRFQSTGKLTG--------HLGPVMCLTVDQISNGQDLIITGSKDHYIKMFD
   WD 4 1423-1468   VTEGALG--TVSPTHNFEPPHYDGIEALAIQ--GD---NLFSGSRDNGIKKWD
   WD 5 1515-1551   -FVPVGE--MRG--------HDSPINAICV--NST---HVFTAADDRTVRIWK

   WD40 Template    TGECLRT--LSG--------HTSGVTSVSFSPDGK---RLVSGSEDGTIKVWD