Accession: ENSMUSP00000114297 - WDRR: WD40 Repeat Recognition

Input parameters:

  Query = ENSMUSP00000114297 (Len=1639)
  Tmplt = WD40-str (Len=40)
  Method = bdp  Gap-open = 50  Gap-extend = 3
  Database = /home/pub/blastdb/nr90  E-value = 0.001  Iteration = 3

Query sequence (ENSMUSP00000114297, Len=1639):

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Query        1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYN 80  
WD40-rpts                                                                                      

Query       81 ATVLAYGQTGAGKTYTMGTGFDTVTSEEEQGIIPRAIAHLFRGIDERKRRAQEKGVTGPEFKVSAQFLELYNEEILDLFD 160 
WD40-rpts                                                                                      

Query      161 STRDPDARHRRSNIKIHEDANGGIYTTGVTSRLINSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRVCA 240 
WD40-rpts                                                                                      

Query      241 QPDLVNETVTGLPDGAAPTGTEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVH 320 
WD40-rpts                                                                                      

Query      321 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMEL 400 
WD40-rpts                                                                                      

Query      401 MEYKAGKRVIGEDGTEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQ 480 
WD40-rpts                                                                                      

Query      481 NYIREIEELRTKLLESEAMNESLRRSLSRASARNPYSLGASPAGPAFGGSPATSMEDASEVIRKAKQDLERLKKKEVRQR 560 
WD40-rpts                                                                                      

Query      561 RKSPEKEAFKKRAKLQAENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADL 640 
WD40-rpts                                                                                      

Query      641 TCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNR 720 
WD40-rpts                                                                                      

Query      721 DLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIR 800 
WD40-rpts                                                                                      

Query      801 ALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGLKPPNMDSGAEVSASTTSSEAESGARSVSSIVRQWNRKIDH 880 
WD40-rpts                                                                                      

Query      881 FLGDRPTATVNGGRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRR 960 
WD40-rpts                                                                                      

Query      961 KREHLQAESPEEEKGLQELAEEIEVLAANIDYINDSITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLK 1040
WD40-rpts                                                                                      

Query     1041 ASIDKGLQVAQKEAQIRLLEGRLRQTDMTGSSQNHLLLDALREKAEAHPELQALIYNVQHENGYASTDEEVSEFSEGSFS 1120
WD40-rpts                                                                                      

Query     1121 QSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDSSTKNITKSLASLVEIKEDGVGFSIRDPYYRDKVSRTVSLP 1200
WD40-rpts                                                                                      

Query     1201 TRGSTFPRQSRGATDTSPLTRRKSYDRGQPIRSTDMGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSE 1280
WD40-rpts                                                                                      

Query     1281 VLRGIITPIGGAKGARTAPLQCISMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCS 1360
WD40-rpts                               (_____________WD 1____________)         (_____________W

Query     1361 HSGLVFSVSSSYIKVWDIRDSAKCIRTLTSSGQVISGDACIATSTRAITSAQGEHQINQMALSPSGSMLYVASGNAVRIW 1440
WD40-rpts      D 2_____________)                                                               

Query     1441 ELNRFQPIGKLTGHIGPVMCLTVTQTSNQHDLVVTGSKDHYVKMFQLGDCVTGTIGPTHNFEPPHYDGIECLAIQGDILF 1520
WD40-rpts       (____________________WD 3___________________)(____________________WD 4_________

Query     1521 SGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGFIKVWNVDNFTPIGEIKGHDSPINAICTNSK 1600
WD40-rpts      ___________)                                               (_______________WD 5_

Query     1601 HIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRATTLP 1639
WD40-rpts      ______________)

5 WD40-repeats found in QUERY=ENSMUSP00000114297 (Len=1639):

(Red - Z-score>4.0)

  Rpts  Segment   Boundary  Z-score   Score  P-value  Identities  SS-score
  WD 1:  Seg 12  1306-1336     3.93  277.04  0.01145       22.5%     27.52
  WD 2:  Seg 15  1346-1377     3.60  263.49  0.01738       30.0%     40.70
  WD 3:  Seg 21  1442-1486     3.44  256.60  0.02148       25.0%     39.91
  WD 4:  Seg 24  1487-1532     4.27  291.05  0.00742       37.5%     19.55
  WD 5:  Seg 29  1580-1615     4.07  282.59  0.00964       22.5%     26.04

Multiple sequence alignment of 5 WD40-repeats:

(BLUE - beta-strands, RED - alpha-helices, predicted by PSIPRED)

   WD 1 1306-1336   ---------AEG--------HTKPILCLDA---TDE--LLFTGSKDRSCKMWN
   WD 2 1346-1377   ---------LKG--------HPNNVVSIKY---CSHSGLVFSVS-SSYIKVWD
   WD 3 1442-1486   LNRFQPIGKLTG--------HIGPVMCLTVTQTSNQHDLVVTGSKDHYVKMFQ
   WD 4 1487-1532   LGDC--VTGTIGPTHNFEPPHYDGIECLAI---Q--GDILFSGSRDNGIKKWD
   WD 5 1580-1615   T--P--IGEIKG--------HDSPINAIC-----TNSKHIFTASSDCRVKLWN

   WD40 Template    TGEC--LRTLSG--------HTSGVTSVSF---SPDGKRLVSGSEDGTIKVWD